Search Results - "Faye, Gerard"
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A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast
Published in PloS one (05-02-2009)“…A mutated allele of the essential gene TAH18 was previously identified in our laboratory in a genetic screen for new proteins interacting with the DNA…”
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2
Oxygen metabolism and reactive oxygen species cause chromosomal rearrangements and cell death
Published in Proceedings of the National Academy of Sciences - PNAS (05-06-2007)“…The absence of Tsa1, a key peroxiredoxin that functions to scavenge H₂O₂ in Saccharomyces cerevisiae, causes the accumulation of a broad spectrum of mutations…”
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Journal Article -
3
Loss of the thioredoxin reductase Trr1 suppresses the genomic instability of peroxiredoxin tsa1 mutants
Published in PloS one (23-09-2014)“…The absence of Tsa1, a key peroxiredoxin that scavenges H2O2 in Saccharomyces cerevisiae, causes the accumulation of a broad spectrum of mutations. Deletion of…”
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Journal Article -
4
Peroxiredoxin Tsa1 is the key peroxidase suppressing genome instability and protecting against cell death in Saccharomyces cerevisiae
Published in PLoS genetics (01-06-2009)“…Peroxiredoxins (Prxs) constitute a family of thiol-specific peroxidases that utilize cysteine (Cys) as the primary site of oxidation during the reduction of…”
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Journal Article -
5
Yeast as a model system to screen purine derivatives against human CDK1 and CDK2 kinases
Published in Journal of biotechnology (10-02-2015)“…Cyclin-dependent kinases (Cdk) play crucial roles in cell cycle progression. Aberrant activation of Cdk1 has been observed in a number of primary tumors and…”
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6
Human peroxiredoxin PrxI is an orthologue of yeast Tsa1, capable of suppressing genome instability in Saccharomyces cerevisiae
Published in Cancer research (Chicago, Ill.) (15-02-2008)“…The peroxiredoxins (Prx) are conserved antioxidant proteins that use cysteine as the primary site of oxidation during the reduction of peroxides. Many…”
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Journal Article -
7
Redox-sensitive YFP sensors monitor dynamic nuclear and cytosolic glutathione redox changes
Published in Free radical biology & medicine (01-06-2012)“…Intracellular redox homeostasis is crucial for many cellular functions but accurate measurements of cellular compartment-specific redox states remain…”
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8
Mutations in MTO2 Related to tRNA Modification Impair Mitochondrial Gene Expression and Protein Synthesis in the Presence of a Paromomycin Resistance Mutation in Mitochondrial 15 S rRNA
Published in The Journal of biological chemistry (12-08-2005)“…Nuclear gene(s) have been shown to modulate the phenotypic expression of mitochondrial DNA mutations. We report here the identification and characterization of…”
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9
Adenosine Monophosphoramidase Activity of Hint and Hnt1 Supports Function of Kin28, Ccl1, and Tfb3
Published in The Journal of biological chemistry (29-03-2002)“…The histidine triad superfamily of nucleotide hydrolases and nucleotide transferases consists of a branch of proteins related to Hint and Aprataxin, a branch…”
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10
Involvement of the yeast DNA polymerase delta in DNA repair in vivo
Published in Genetics (Austin) (01-08-1997)“…The POL3 encoded catalytic subunit of DNA polymerase delta possesses a highly conserved C-terminal cysteine-rich domain in Saccharomyces cerevisiae. Mutations…”
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11
Kinase Cak1 functionally interacts with the PAF1 complex and phosphatase Ssu72 via kinases Ctk1 and Bur1
Published in Molecular genetics and genomics : MGG (01-02-2006)“…Protein kinases orthologous with Cak1 of Saccharomyces cerevisiae (ScCak1) appear specific to ascomycetes. ScCak1 phosphorylates Cdc28, the cyclin-dependent…”
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12
Protein interaction mapping: a Drosophila case study
Published in Genome research (01-03-2005)“…The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a…”
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13
Mitochondrial splicing requires a protein from a novel helicase family
Published in Nature (London) (05-01-1989)“…Proteins involved in mitochondrial splicing but encoded by nuclear genes have been characterized in Saccharomyces and Neurospora. The role in splicing of these…”
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14
Retention Strategies for Oil and Gas Industry Managers
Published 01-01-2019“…The turnover cost of specialized employees in the oil and gas industry can exceed 400% of an employee’s annual salary. The purpose of this multiple case study…”
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Dissertation -
15
Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast
Published in The EMBO journal (01-04-2003)“…Ssu72 is an essential yeast protein that is involved in transcription. It physically interacts with transcription initiation and termination complexes. In this…”
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Xbp1-Mediated Repression of CLB Gene Expression Contributes to the Modifications of Yeast Cell Morphology and Cell Cycle Seen during Nitrogen-Limited Growth
Published in Molecular and Cellular Biology (01-06-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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17
MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase
Published in Journal of molecular biology (05-07-1993)“…Mutations in the MSS1 gene render the yeast cells respiratory deficient only in the presence of the PR454 mutation (paromomycin resistance) in the…”
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18
Distinct activated and non-activated RNA polymerase II complexes in yeast
Published in The EMBO journal (02-09-1996)“…We used a transcriptional run-on assay in permeabilized yeast cells to study the distribution of RNA polymerase II (pol II) complexes before and after…”
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Journal Article -
19
Peroxiredoxin Tsa1 Is the Key Peroxidase Suppressing Genome Instability and Protecting against Cell Death in Saccharomyces cerevisiae: e1000524
Published in PLoS genetics (01-06-2009)“…Peroxiredoxins (Prxs) constitute a family of thiol-specific peroxidases that utilize cysteine (Cys) as the primary site of oxidation during the reduction of…”
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Journal Article -
20
Human peroxiredoxin PrxI is an ortholog of yeast Tsa1, capable of suppressing genome instability and protecting against cell death in Saccharomyces cerevisiae
Published in Cancer research (Chicago, Ill.) (15-02-2008)“…The peroxiredoxins (Prxs) are conserved antioxidant proteins that utilize cysteine as the primary site of oxidation during the reduction of peroxides. Many…”
Get full text
Journal Article