Search Results - "Fay, P."

A Systematic Review and Meta-analysis of Adjuvant and Neoadjuvant Chemotherapy for Upper Tract Urothelial Carcinoma by Leow, Jeffrey J, Martin-Doyle, William, Fay, André P, Choueiri, Toni K, Chang, Steven L, Bellmunt, Joaquim

“…Abstract Context The role of adjuvant chemotherapy (AC) or neoadjuvant chemotherapy (NC) remains poorly defined for the management of upper tract urothelial…”
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Exact and Asymptotic Weighted Logrank Tests for Interval Censored Data: The interval R package by Fay, Michael P, Shaw, Pamela A

“…For right-censored data perhaps the most commonly used tests are weighted logrank tests, such as the logrank and Wilcoxon-type tests. In this paper we review…”
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Standardization of ELISA protocols for serosurveys of the SARS-CoV-2 pandemic using clinical and at-home blood sampling by Klumpp-Thomas, Carleen, Kalish, Heather, Drew, Matthew, Hunsberger, Sally, Snead, Kelly, Fay, Michael P., Mehalko, Jennifer, Shunmugavel, Anandakumar, Wall, Vanessa, Frank, Peter, Denson, John-Paul, Hong, Min, Gulten, Gulcin, Messing, Simon, Hicks, Jennifer, Michael, Sam, Gillette, William, Hall, Matthew D., Memoli, Matthew J., Esposito, Dominic, Sadtler, Kaitlyn

“…The extent of SARS-CoV-2 infection throughout the United States population is currently unknown. High quality serology is key to avoiding medically costly…”
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Mutations in TSC1, TSC2, and MTOR Are Associated with Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma by Kwiatkowski, David J, Choueiri, Toni K, Fay, André P, Rini, Brian I, Thorner, Aaron R, de Velasco, Guillermo, Tyburczy, Magdalena E, Hamieh, Lana, Albiges, Laurence, Agarwal, Neeraj, Ho, Thai H, Song, Jiaxi, Pignon, Jean-Christophe, Barrios, Pablo M, Michaelson, M Dror, Van Allen, Eliezer, Krajewski, Katherine M, Porta, Camillo, Pal, Sumanta, Bellmunt, Joaquim, McDermott, David F, Heng, Daniel Y C, Gray, Kathryn P, Signoretti, Sabina

“…We examined the hypothesis that mutations in mTOR pathway genes are associated with response to rapalogs in metastatic renal cell carcinoma (mRCC). We studied…”
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Change in Neutrophil-to-lymphocyte Ratio in Response to Targeted Therapy for Metastatic Renal Cell Carcinoma as a Prognosticator and Biomarker of Efficacy by Templeton, Arnoud J, Knox, Jennifer J, Lin, Xun, Simantov, Ronit, Xie, Wanling, Lawrence, Nicola, Broom, Reuben, Fay, André P, Rini, Brian, Donskov, Frede, Bjarnason, Georg A, Smoragiewicz, Martin, Kollmannsberger, Christian, Kanesvaran, Ravindran, Alimohamed, Nimira, Hermanns, Thomas, Wells, J. Connor, Amir, Eitan, Choueiri, Toni K, Heng, Daniel Y.C

“…Abstract Background Neutrophil-to-lymphocyte ratio (NLR), if elevated, is associated with worse outcomes in several malignancies. Objective Investigation of…”
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Dihydroartemisinin–piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study by Amaratunga, Chanaki, PhD, Lim, Pharath, PhD, Suon, Seila, MD, Sreng, Sokunthea, Mao, Sivanna, MD, Sopha, Chantha, MD, Sam, Baramey, MD, Dek, Dalin, BA, Try, Vorleak, BA, Amato, Roberto, PhD, Blessborn, Daniel, PhD, Song, Lijiang, PhD, Tullo, Gregory S, BS, Fay, Michael P, PhD, Anderson, Jennifer M, PhD, Tarning, Joel, PhD, Fairhurst, Rick M, Dr

“…Summary Background Artemisinin resistance in Plasmodium falciparum threatens to reduce the efficacy of artemisinin combination therapies (ACTs), thus…”
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Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States by Kalish, Heather, Klumpp-Thomas, Carleen, Hunsberger, Sally, Baus, Holly Ann, Fay, Michael P, Siripong, Nalyn, Wang, Jing, Hicks, Jennifer, Mehalko, Jennifer, Travers, Jameson, Drew, Matthew, Pauly, Kyle, Spathies, Jacquelyn, Ngo, Tran, Adusei, Kenneth M, Karkanitsa, Maria, Croker, Jennifer A, Li, Yan, Graubard, Barry I, Czajkowski, Lindsay, Belliveau, Olivia, Chairez, Cheryl, Snead, Kelly R, Frank, Peter, Shunmugavel, Anandakumar, Han, Alison, Giurgea, Luca T, Rosas, Luz Angela, Bean, Rachel, Athota, Rani, Cervantes-Medina, Adriana, Gouzoulis, Monica, Heffelfinger, Brittany, Valenti, Shannon, Caldararo, Rocco, Kolberg, Michelle M, Kelly, Andrew, Simon, Reid, Shafiq, Saifullah, Wall, Vanessa, Reed, Susan, Ford, Eric W, Lokwani, Ravi, Denson, John-Paul, Messing, Simon, Michael, Sam G, Gillette, William, Kimberly, Robert P, Reis, Steven E, Hall, Matthew D, Esposito, Dominic, Memoli, Matthew J, Sadtler, Kaitlyn

“…Asymptomatic SARS-CoV-2 infection and delayed implementation of diagnostics have led to poorly defined viral prevalence rates in the United States and…”
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Correlation of PD-L1 tumor expression and treatment outcomes in patients with renal cell carcinoma receiving sunitinib or pazopanib: results from COMPARZ, a randomized controlled trial by Choueiri, Toni K, Figueroa, David J, Fay, André P, Signoretti, Sabina, Liu, Yuan, Gagnon, Robert, Deen, Keith, Carpenter, Christopher, Benson, Peter, Ho, Thai H, Pandite, Lini, de Souza, Paul, Powles, Thomas, Motzer, Robert J

“…The interaction of programmed death-1 ligand (PD-L1) with its receptor (PD-1) on T cells inactivates antitumor immune responses. PD-L1 expression has been…”
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Differential Expression of PD-L1 between Primary and Metastatic Sites in Clear-Cell Renal Cell Carcinoma by Callea, Marcella, Albiges, Laurence, Gupta, Mamta, Cheng, Su-Chun, Genega, Elizabeth M, Fay, André P, Song, Jiaxi, Carvo, Ingrid, Bhatt, Rupal S, Atkins, Michael B, Hodi, F Stephen, Choueiri, Toni K, McDermott, David F, Freeman, Gordon J, Signoretti, Sabina

“…PD-L1 expression in primary clear-cell renal cell carcinoma (ccRCC) increases the likelihood of response to anti-PD-1 inhibition, but fails to identify all…”
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Efficacy of targeted therapies after PD-1/PD-L1 blockade in metastatic renal cell carcinoma by Albiges, Laurence, Fay, André P, Xie, Wanling, Krajewski, Katherine, McDermott, David F, Heng, Daniel Y.C, Dariane, Charles, DeVelasco, Guillermo, Lester, Renee, Escudier, Bernard, Choueiri, Toni K

“…Highlights • The efficacy of targeted therapy (TT) after PD-1/ PD-L1 blockade is unknown in mRCC. • We conducted a retrospective analysis of mRCC patients…”
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Climate Change, Elevational Range Shifts, and Bird Extinctions by SEKERCIOGLU, CAGAN H., SCHNEIDER, STEPHEN H., FAY, JOHN P., LOARIE, SCOTT R.

“…Limitations imposed on species ranges by the climatic, ecological, and physiological effects of elevation are important determinants of extinction risk. We…”
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In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies by Peters, Nathan C, Egen, Jackson G, Secundino, Nagila, Debrabant, Alain, Kimblin, Nicola, Kamhawi, Shaden, Lawyer, Phillip, Fay, Michael P, Germain, Ronald N, Sacks, David

“…Infection with the obligate intracellular protozoan Leishmania is thought to be initiated by direct parasitization of macrophages, but the early events…”
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Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome by Khoukaz, Hekmat B., Ji, Yan, Braet, Drew J., Vadali, Manisha, Abdelhamid, Ahmed A., Emal, Cory D., Lawrence, Daniel A., Fay, William P.

“…OBJECTIVE:Enhanced expression of PAI-1 (plasminogen activator inhibitor-1) has been implicated in atherosclerosis formation in humans with obesity and…”
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Body Mass Index and Metastatic Renal Cell Carcinoma: Clinical and Biological Correlations by Albiges, Laurence, Hakimi, A Ari, Xie, Wanling, McKay, Rana R, Simantov, Ronit, Lin, Xun, Lee, Jae-Lyun, Rini, Brian I, Srinivas, Sandy, Bjarnason, Georg A, Ernst, Scott, Wood, Lori A, Vaishamayan, Ulka N, Rha, Sun-Young, Agarwal, Neeraj, Yuasa, Takeshi, Pal, Sumanta K, Bamias, Aristotelis, Zabor, Emily C, Skanderup, Anders J, Furberg, Helena, Fay, Andre P, de Velasco, Guillermo, Preston, Mark A, Wilson, Kathryn M, Cho, Eunyoung, McDermott, David F, Signoretti, Sabina, Heng, Daniel Y C, Choueiri, Toni K

“…Obesity is an established risk factor for clear cell renal cell carcinoma (RCC); however, some reports suggest that RCC developing in obese patients may be…”
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Analysis of ordered composite endpoints by Follmann, Dean, Fay, Michael P, Hamasaki, Toshimitsu, Evans, Scott

“…Composite endpoints are frequently used in clinical trials, but simple approaches, such as the time to first event, do not reflect any ordering among the…”
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PD-L1 expression in nonclear-cell renal cell carcinoma by Choueiri, T.K., Fay, A.P., Gray, K.P., Callea, M., Ho, T.H., Albiges, L., Bellmunt, J., Song, J., Carvo, I., Lampron, M., Stanton, M.L., Hodi, F.S., McDermott, D.F., Atkins, M.B., Freeman, G.J., Hirsch, M.S., Signoretti, S.

“…Programmed death ligand-1 (PD-L1) expression in nonclear-cell RCC (non-ccRCC) and its association with clinical outcomes are unknown. Formalin-fixed…”
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Kinetics of the xanthophyll cycle and its role in photoprotective memory and response by Short, Audrey, Fay, Thomas P., Crisanto, Thien, Mangal, Ratul, Niyogi, Krishna K., Limmer, David T., Fleming, Graham R.

“…Efficiently balancing photochemistry and photoprotection is crucial for survival and productivity of photosynthetic organisms in the rapidly fluctuating light…”
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Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay by Miura, Kazutoyo, Swihart, Bruce J, Deng, Bingbing, Zhou, Luwen, Pham, Thao P, Diouf, Ababacar, Burton, Timothy, Fay, Michael P, Long, Carole A

“…Abstract Malaria transmission-blocking vaccines (TBVs) are potentially helpful tools for malaria eradication. The standard membrane-feeding assay (SMFA) is…”
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Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine by Sá, Juliana Martha, Twu, Olivia, Hayton, Karen, Reyes, Sahily, Fay, Michael P, Ringwald, Pascal, Wellems, Thomas E

“…Chloroquine (CQ) resistance (CQR) in Plasmodium falciparum originated from at least six foci in South America, Asia, and Oceania. Malaria parasites from these…”
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Qualification of standard membrane-feeding assay with Plasmodium falciparum malaria and potential improvements for future assays by Miura, Kazutoyo, Deng, Bingbing, Tullo, Gregory, Diouf, Ababacar, Moretz, Samuel E, Locke, Emily, Morin, Merribeth, Fay, Michael P, Long, Carole A

“…Vaccines that interrupt malaria transmission are of increasing interest and a robust functional assay to measure this activity would promote their development…”
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