Search Results - "Fay, Nicole C."

Myosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formation by Yu, Yan, Fay, Nicole C, Smoligovets, Alexander A, Wu, Hung-Jen, Groves, Jay T

“…Activation of T cell receptor (TCR) by antigens occurs in concert with an elaborate multi-scale spatial reorganization of proteins at the immunological…”
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Mapping the stochastic sequence of individual ligand-receptor binding events to cellular activation: T cells act on the rare events by Lin, Jenny J Y, Low-Nam, Shalini T, Alfieri, Katherine N, McAffee, Darren B, Fay, Nicole C, Groves, Jay T

“…T cell receptor (TCR) binding to agonist peptide major histocompatibility complex (pMHC) triggers signaling events that initiate T cell responses. This system…”
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Early T cell receptor signals globally modulate ligand: receptor affinities during antigen discrimination by Pielak, Rafal M., O’Donoghue, Geoff P., Lin, Jenny J., Alfieri, Katherine N., Fay, Nicole C., Low-Nam, Shalini T., Groves, Jay T.

“…Antigen discrimination by T cells occurs at the junction between a T cell and an antigen-presenting cell. Juxtacrine binding between numerous adhesion,…”
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A Novel Fusion of IL-10 Engineered to Traffic across Intestinal Epithelium to Treat Colitis by Fay, Nicole C, Muthusamy, Baby-Periyanayaki, Nyugen, Linh P, Desai, Radhika C, Taverner, Alistair, MacKay, Julia, Seung, Minji, Hunter, Tom, Liu, Keyi, Chandalia, Apurva, Coyle, Michael P, Kim, Hyojin L, Postlethwaite, Sally, Mangat, Khushdeep, Song, Lisa, Seto, Elbert, Alam, Aatif, Olson, Charles V, Feng, Weijun, Saberi, Maziyar, Mahmood, Tahir A, Mrsny, Randall J

“…IL-10 is a potent anti-inflammatory cytokine capable of suppressing a number of proinflammatory signals associated with intestinal inflammatory diseases, such…”
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Membrane Association Transforms an Inert Anti-TCRβ Fab’ Ligand into a Potent T Cell Receptor Agonist by Lin, Jenny J., O’Donoghue, Geoff P., Wilhelm, Kiera B., Coyle, Michael P., Low-Nam, Shalini T., Fay, Nicole C., Alfieri, Katherine N., Groves, Jay T.

“…The natural peptide-major histocompatibility complex (pMHC) ligand for T cell receptors (TCRs) is inactive from solution yet capable of activating T cells at…”
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Cellular binding, motion, and internalization of synthetic gene delivery polymers by Hess, Gaelen T., Humphries, William H., Fay, Nicole C., Payne, Christine K.

“…Using fluorescence microscopy we have tracked the cellular binding, surface motion, and internalization of polyarginine and polyethylenimine, cationic ligands…”
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Intracellular degradation of low-density lipoprotein probed with two-color fluorescence microscopy by Humphries, 4th, William H, Fay, Nicole C, Payne, Christine K

“…The intracellular vesicle-mediated degradation of extracellular cargo is an essential cellular function. Using two-color single particle tracking fluorescence…”
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T Cell Costimulatory Response and Receptor Dynamics Determined by Ligand Engagement by Fay, Nicole C., Alfieri, Katherine, Kai, Hiro, Groves, Jay

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The Effect of Costimulation on T Cell Receptor Dynamics by Fay, Nicole C., Alfieri, Katherine N., Groves, Jay T.

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SNAP-tag Fusion Proteins as a Platform for Studying T Cell Costimulation by Alfieri, Katherine N., Fay, Nicole C., Groves, Jay T.

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Non-Muscle Myosin IIA at the Immunological Synapse: Integration of Mechanical Regulation with T Cell Signaling by Yu, Yan, Fay, Nicole C., Smoligovets, Alexander A., Wu, Hung-Jen, Groves, Jay T.

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Intracellular degradation of low-density lipoprotein probed with two-color fluorescence microscopyElectronic supplementary information (ESI) available: Figures S1-S4. See DOI: 10.1039/c0ib00035c by Humphries IV, William H, Fay, Nicole C, Payne, Christine K

“…The intracellular vesicle-mediated degradation of extracellular cargo is an essential cellular function. Using two-color single particle tracking fluorescence…”
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Corrigendum to “Cellular binding, motion, and internalization of synthetic gene delivery polymers” [Biochim. Biophys. Acta 1773 (2007) 1583–1588] by Hess, Gaelen T., Humphries, William H., Fay, Nicole C., Payne, Christine K.

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