Search Results - "Fay, Francois"
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Nanomedicine-based delivery strategies for nucleic acid gene inhibitors in inflammatory diseases
Published in Advanced drug delivery reviews (01-08-2021)“…[Display omitted] Thanks to their abilities to modulate the expression of virtually any genes, RNA therapeutics have attracted considerable research efforts…”
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Comparative assessment of control strategies for the biradial turbine in the Mutriku OWC plant
Published in Renewable energy (01-02-2020)“…To be competitive against other renewable energy sources, energy converted from the ocean waves needs to reduce its associated levelised cost of energy. It has…”
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Sea trial results of a predictive algorithm at the Mutriku Wave power plant and controllers assessment based on a detailed plant model
Published in Renewable energy (01-02-2020)“…Improving the power production in wave energy plants is essential to lower the cost of energy production from this type of installations. Oscillating Water…”
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Amphiphilic Phosphorus Dendrons Associated with Anti-inflammatory siRNA Reduce Symptoms in Murine Collagen-Induced Arthritis
Published in Biomacromolecules (13-02-2023)“…Small interfering RNA (siRNA) holds promise for treating rheumatoid arthritis by inhibiting major cytokines such as tumor necrosis factor-α (TNF-α). We…”
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5
Bisphosphonate Liposomes for Cobalt and Strontium Decorporation?
Published in Health physics (1958) (01-10-2024)“…During a nuclear/radiological incident or an accident involving internal intakes with radioactive cobalt or strontium, the recommended treatments, consisting…”
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Analysis of electrical drive speed control limitations of a power take-off system for wave energy converters
Published in Renewable energy (01-12-2017)“…The active control of wave energy converters with oil-hydraulic power take-off systems presents important demands on the electrical drives attached to their…”
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An Iterative Refining Approach to Design the Control of Wave Energy Converters with Numerical Modeling and Scaled HIL Testing
Published in Energies (Basel) (01-05-2020)“…The aim of this work is to show that a significant increase of the efficiency of a Wave Energy Converter (WEC) can be achieved already at an early design…”
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Speed control of oil-hydraulic power take-off system for oscillating body type wave energy converters
Published in Renewable energy (01-11-2016)“…The variable displacement oil-hydraulic pumps for the Power Take-Off (PTO) of wave energy converters must work above 80% of maximum displacement in order to…”
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Nanotechnologies and controlled release formulations for the administration of bisphosphonates and their potential in radiation protection
Published in Journal of drug delivery science and technology (01-12-2023)“…In the event of internal contamination with radionuclides, decorporating treatment is crucial. It must be initiated as soon as possible to limit tissue…”
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10
Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease
Published in Nature communications (16-01-2017)“…Tissue macrophage numbers vary during health versus disease. Abundant inflammatory macrophages destruct tissues, leading to atherosclerosis, myocardial…”
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Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis
Published in Proceedings of the National Academy of Sciences - PNAS (21-01-2014)“…Therapeutic and diagnostic nanomaterials are being intensely studied for several diseases, including cancer and atherosclerosis. However, the exact mechanism…”
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Single Step Reconstitution of Multifunctional High-Density Lipoprotein-Derived Nanomaterials Using Microfluidics
Published in ACS nano (26-11-2013)“…High-density lipoprotein (HDL) is a natural nanoparticle that transports peripheral cholesterol to the liver. Reconstituted high-density lipoprotein (rHDL)…”
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Atherosclerotic Plaque Targeting Mechanism of Long-Circulating Nanoparticles Established by Multimodal Imaging
Published in ACS nano (24-02-2015)“…Atherosclerosis is a major cause of global morbidity and mortality that could benefit from novel targeted therapeutics. Recent studies have shown efficient and…”
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Real‐Time Monitoring of Nanoparticle Formation by FRET Imaging
Published in Angewandte Chemie International Edition (06-03-2017)“…Understanding the formation process of nanoparticles is of the utmost importance to improve their design and production. This especially holds true for…”
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Enhanced Antitumor Activity of the Photosensitizer meso-Tetra(N‑methyl-4-pyridyl) Porphine Tetra Tosylate through Encapsulation in Antibody-Targeted Chitosan/Alginate Nanoparticles
Published in Biomacromolecules (11-02-2013)“…meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate (TMP) is a photosensitizer that can be used in photodynamic therapy (PDT) to induce cell death through…”
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Near-Infrared Fluorescence Energy Transfer Imaging of Nanoparticle Accumulation and Dissociation Kinetics in Tumor-Bearing Mice
Published in ACS nano (26-11-2013)“…In the current study we show the dissociation and tumor accumulation dynamics of dual-labeled near-infrared quantum dot core self-assembled lipidic…”
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Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation
Published in Science advances (01-04-2015)“…Inflammation drives atherosclerotic plaque progression and rupture, and is a compelling therapeutic target. Consequently, attenuating inflammation by reducing…”
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Antibody Targeting of Camptothecin-Loaded PLGA Nanoparticles to Tumor Cells
Published in Bioconjugate chemistry (01-08-2008)“…Antibody targeting of drug substances can improve the efficacy of the active molecule, improving distribution and concentration of the drug at the site of…”
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Multimodal Positron Emission Tomography Imaging to Quantify Uptake of 89Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall
Published in Bioconjugate chemistry (19-02-2020)“…Nanotherapy has recently emerged as an experimental treatment option for atherosclerosis. To fulfill its promise, robust noninvasive imaging approaches for…”
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Gene delivery using dimethyldidodecylammonium bromide-coated PLGA nanoparticles
Published in Biomaterials (01-05-2010)“…Abstract In this present work we describe a poly(lactic- co -glycolic acid) (PLGA) nanoparticle formulation for intracellular delivery of plasmid DNA. This…”
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