Search Results - "Favuzzi, Emilia"

Molecular diversity underlying cortical excitatory and inhibitory synapse development by Favuzzi, Emilia, Rico, Beatriz

“…•Molecular diversity critically contributes to synapse diversity.•Different molecules regulate excitatory and inhibitory synapse development.•Synapse…”
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Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits by Favuzzi, Emilia, Deogracias, Rubén, Marques-Smith, André, Maeso, Patricia, Jezequel, Julie, Exposito-Alonso, David, Balia, Maddalena, Kroon, Tim, Hinojosa, Antonio J, F Maraver, Elisa, Rico, Beatriz

“…How neuronal connections are established and organized into functional networks determines brain function. In the mammalian cerebral cortex, different classes…”
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Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican by Favuzzi, Emilia, Marques-Smith, André, Deogracias, Rubén, Winterflood, Christian M., Sánchez-Aguilera, Alberto, Mantoan, Laura, Maeso, Patricia, Fernandes, Cathy, Ewers, Helge, Rico, Beatriz

“…Activity-dependent neuronal plasticity is a fundamental mechanism through which the nervous system adapts to sensory experience. Several lines of evidence…”
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Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing by Ibrahim, Leena Ali, Wamsley, Brie, Alghamdi, Norah, Yusuf, Nusrath, Sevier, Elaine, Hairston, Ariel, Sherer, Mia, Jaglin, Xavier Hubert, Xu, Qing, Guo, Lihua, Khodadadi-Jamayran, Alireza, Favuzzi, Emilia, Yuan, Yuan, Dimidschstein, Jordane, Darnell, Robert B, Fishell, Gordon

“…Somatostatin interneurons are the earliest born population of cortical inhibitory cells. They are crucial to support normal brain development and function;…”
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Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis by Annibali, Daniela, Whitfield, Jonathan R., Favuzzi, Emilia, Jauset, Toni, Serrano, Erika, Cuartas, Isabel, Redondo-Campos, Sara, Folch, Gerard, Gonzàlez-Juncà, Alba, Sodir, Nicole M., Massó-Vallés, Daniel, Beaulieu, Marie-Eve, Swigart, Lamorna B., Mc Gee, Margaret M., Somma, Maria Patrizia, Nasi, Sergio, Seoane, Joan, Evan, Gerard I., Soucek, Laura

“…Gliomas are the most common primary tumours affecting the adult central nervous system and respond poorly to standard therapy. Myc is causally implicated in…”
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The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy by Savino, Mauro, Annibali, Daniela, Carucci, Nicoletta, Favuzzi, Emilia, Cole, Michael D, Evan, Gerard I, Soucek, Laura, Nasi, Sergio

“…Recent evidence points to Myc--a multifaceted bHLHZip transcription factor deregulated in the majority of human cancers--as a priority target for therapy. How…”
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The brain's polymath: Emerging roles of microglia throughout brain development by Wong, Fong Kuan, Favuzzi, Emilia

“…Microglia, the resident brain immune cells, have garnered a reputation as major effectors of circuit wiring due to their ability to prune synapses. Other roles…”
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GABA-receptive microglia selectively sculpt developing inhibitory circuits by Favuzzi, Emilia, Huang, Shuhan, Saldi, Giuseppe A., Binan, Loïc, Ibrahim, Leena A., Fernández-Otero, Marian, Cao, Yuqing, Zeine, Ayman, Sefah, Adwoa, Zheng, Karen, Xu, Qing, Khlestova, Elizaveta, Farhi, Samouil L., Bonneau, Richard, Datta, Sandeep Robert, Stevens, Beth, Fishell, Gord

“…Microglia, the resident immune cells of the brain, have emerged as crucial regulators of synaptic refinement and brain wiring. However, whether the remodeling…”
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Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons by Wamsley, Brie, Jaglin, Xavier Hubert, Favuzzi, Emilia, Quattrocolo, Giulia, Nigro, Maximiliano José, Yusuf, Nusrath, Khodadadi-Jamayran, Alireza, Rudy, Bernardo, Fishell, Gord

“…Cortical interneurons display a remarkable diversity in their morphology, physiological properties, and connectivity. Elucidating the molecular determinants…”
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Shaping Early Networks to Rule Mature Circuits: Little MiRs Go a Long Way by Marques-Smith, Andre, Favuzzi, Emilia, Rico, Beatriz

“…Normative cortical processing depends on precise interactions between excitatory and inhibitory neurons. In this issue of Neuron, Lippi et al. (2016) identify…”
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Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans by Vormstein-Schneider, Douglas, Lin, Jessica D., Pelkey, Kenneth A., Chittajallu, Ramesh, Guo, Baolin, Arias-Garcia, Mario A., Allaway, Kathryn, Sakopoulos, Sofia, Schneider, Gates, Stevenson, Olivia, Vergara, Josselyn, Sharma, Jitendra, Zhang, Qiangge, Franken, Tom P., Smith, Jared, Ibrahim, Leena A., Mastro, Kevin J., Sabri, Ehsan, Huang, Shuhan, Favuzzi, Emilia, Burbridge, Timothy, Xu, Qing, Guo, Lihua, Vogel, Ian, Sanchez, Vanessa, Saldi, Giuseppe A., Gorissen, Bram L., Yuan, Xiaoqing, Zaghloul, Kareem A., Devinsky, Orrin, Sabatini, Bernardo L., Batista-Brito, Renata, Reynolds, John, Feng, Guoping, Fu, Zhanyan, McBain, Chris J., Fishell, Gord, Dimidschstein, Jordane

“…Recent success in identifying gene-regulatory elements in the context of recombinant adeno-associated virus vectors has enabled cell-type-restricted gene…”
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GABA-receptive microglia selectively sculpt developing inhibitory circuits by Favuzzi, Emilia, Huang, Shuhan, Saldi, Giuseppe A., Binan, Loïc, Ibrahim, Leena A., Fernández-Otero, Marian, Cao, Yuqing, Zeine, Ayman, Sefah, Adwoa, Zheng, Karen, Xu, Qing, Khlestova, Elizaveta, Farhi, Samouil L., Bonneau, Richard, Datta, Sandeep Robert, Stevens, Beth, Fishell, Gord

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Microglia contribute to the postnatal development of cortical somatostatin-positive inhibitory cells and to whisker-evoked cortical activity by Gesuita, Lorenzo, Cavaccini, Anna, Argunsah, Ali Özgür, Favuzzi, Emilia, Ibrahim, Leena Ali, Stachniak, Tevye Jason, De Gennaro, Martina, Utz, Sebastian, Greter, Melanie, Karayannis, Theofanis

“…Microglia play a key role in shaping the formation and refinement of the excitatory network of the brain. However, less is known about whether and how they…”
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Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time by Prakash, Priya, Jethava, Krupal P, Korte, Nils, Izquierdo, Pablo, Favuzzi, Emilia, Rose, Indigo V. L, Guttenplan, Kevin A, Manchanda, Palak, Dutta, Sayan, Rochet, Jean-Christophe, Fishell, Gord, Liddelow, Shane A, Attwell, David, Chopra, Gaurav

“…Phagocytosis by glial cells is essential to regulate brain function during health and disease. Therapies for Alzheimer's disease (AD) have primarily focused on…”
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Publisher Correction: Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans by Vormstein-Schneider, Douglas, Lin, Jessica D., Pelkey, Kenneth A., Chittajallu, Ramesh, Guo, Baolin, Arias-Garcia, Mario A., Allaway, Kathryn, Sakopoulos, Sofia, Schneider, Gates, Stevenson, Olivia, Vergara, Josselyn, Sharma, Jitendra, Zhang, Qiangge, Franken, Tom P., Smith, Jared, Ibrahim, Leena A., Mastro, Kevin J., Sabri, Ehsan, Huang, Shuhan, Favuzzi, Emilia, Burbridge, Timothy, Xu, Qing, Guo, Lihua, Vogel, Ian, Sanchez, Vanessa, Saldi, Giuseppe A., Gorissen, Bram L., Yuan, Xiaoqing, Zaghloul, Kareem A., Devinsky, Orrin, Sabatini, Bernardo L., Batista-Brito, Renata, Reynolds, John, Feng, Guoping, Fu, Zhanyan, McBain, Chris J., Fishell, Gord, Dimidschstein, Jordane

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Abstract 1085: MYC inhibition is a potent therapy against glioma and induces mitotic crisis in cancer cells by Annibali, Daniela, Whitfield, Jonathan R., Favuzzi, Emilia, Jauset, Toni, serrano, Erika, Folch, Gerard, Cuartas, Marta I., Gonzalez, Alba, Brown Swigart, Lamorna, Nasi, Sergio, Evan, Gerard I., Seoane, Joan, Soucek, Laura

“…Abstract Gliomas are the most common primary tumors affecting the adult human Central Nervous System (CNS). The most lethal is grade IV glioblastoma (GBM),…”
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