Search Results - "Favret, Jeremy"
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Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-2016)“…Applying clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated protein 9 (Cas9)-mediated mutagenesis to primary mouse immune…”
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Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells
Published in Science (American Association for the Advancement of Science) (12-02-2016)“…Differentiated macrophages can self-renew in tissues and expand long term in culture, but the gene regulatory mechanisms that accomplish self-renewal in the…”
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Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo
Published in Nature immunology (01-03-2022)“…Alveolar macrophages (AMs) are lung tissue-resident macrophages that can be expanded in culture, but it is unknown to what extent culture affects their in vivo…”
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SIRT1 regulates macrophage self‐renewal
Published in The EMBO journal (15-08-2017)“…Mature differentiated macrophages can self‐maintain by local proliferation in tissues and can be extensively expanded in culture under specific conditions, but…”
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Isolation and Long-term Cultivation of Mouse Alveolar Macrophages
Published in Bio-protocol (20-07-2019)“…Alveolar macrophages (AM) are tissue-resident macrophages that colonize the lung around birth and can self-maintain long-term in an adult organism without…”
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Progressive replacement of embryo-derived cardiac macrophages with age
Published in The Journal of experimental medicine (20-10-2014)“…Cardiac macrophages (cMΦ) are critical for early postnatal heart regeneration and fibrotic repair in the adult heart, but their origins and cellular dynamics…”
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Isolation, Ex Vivo Expansion, and Lentiviral Transduction of Alveolar Macrophages
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Alveolar macrophages (AM) are resident macrophages of the lung and play important roles in the maintenance of tissue homeostasis as well as host defense. Here,…”
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