Search Results - "Favaloro, Frank G."

Tricyclic Compounds Containing Nonenolizable Cyano Enones. A Novel Class of Highly Potent Anti-Inflammatory and Cytoprotective Agents by Honda, Tadashi, Yoshizawa, Hidenori, Sundararajan, Chitra, David, Emilie, Lajoie, Marc J, Favaloro, Frank G, Janosik, Tomasz, Su, Xiaobo, Honda, Yukiko, Roebuck, Bill D, Gribble, Gordon W

“…Forty-four novel tricycles containing nonenolizable cyano enones (TCEs) were designed and synthesized on the basis of a semisynthetic pentacyclic triterpenoid,…”
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A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production by HONDA, Tadashi, HONDA, Yukiko, FAVALORO, Frank G, GRIBBLE, Gordon W, SUH, Nanjoo, PLACE, Andrew E, RENDI, Mara H, SPORN, Michael B

“…New oleanane triterpenoids with various substituents at the C-17 position of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO) and methyl…”
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Efficient synthesis of (-)- and (+)-tricyclic compounds with enone functionalities in rings A and C. A novel class of orally active anti-inflammatory and cancer chemopreventive agents by Honda, Tadashi, Favaloro, Jr, Frank G, Janosik, Tomasz, Honda, Yukiko, Suh, Nanjoo, Sporn, Michael B, Gribble, Gordon W

“…Novel tricyclic compounds with enone functionalities in rings A and C [tricyclic-bis-enone (TBE) compounds] were designed on the basis of the structure of a…”
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Design and Synthesis of Tricyclic Compounds with Enone Functionalities in Rings A and C:  A Novel Class of Highly Active Inhibitors of Nitric Oxide Production in Mouse Macrophages by Favaloro, Frank G, Honda, Tadashi, Honda, Yukiko, Gribble, Gordon W, Suh, Nanjoo, Risingsong, Renee, Sporn, Michael B

“…Novel tricyclic compounds with enone functionalities in rings A and C, which were designed on the basis of the structure of a synthetic triterpenoid,…”
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Study on the Base-Catalyzed Reverse Vinylogous Aldol Reaction of (4aβ,5β)-4,4a,5,6,7,8-Hexahydro- 5-hydroxy-1,4a-dimethylnaphthalen-2(3H)-one under Robinson Annulation Conditions by Payette, Joshua N, Honda, Tadashi, Yoshizawa, Hidenori, Favaloro, Frank G, Gribble, Gordon W

“…We have proposed a pathway for the base-catalyzed reverse vinylogous aldol reaction of…”
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Synthetic Oleanane and Ursane Triterpenoids with Modified Rings A and C:  A Series of Highly Active Inhibitors of Nitric Oxide Production in Mouse Macrophages by Honda, Tadashi, Rounds, BarbieAnn V, Bore, Lothar, Finlay, Heather J, Favaloro, Frank G, Suh, Nanjoo, Wang, Yongping, Sporn, Michael B, Gribble, Gordon W

“…We have designed and synthesized 16 new olean- and urs-1-en-3-one triterpenoids with various modified rings C as potential antiinflammatory and cancer…”
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Novel Synthetic Oleanane and Ursane Triterpenoids with Various Enone Functionalities in Ring A as Inhibitors of Nitric Oxide Production in Mouse Macrophages by Honda, Tadashi, Gribble, Gordon W, Suh, Nanjoo, Finlay, Heather J, Rounds, BarbieAnn V, Bore, Lothar, Favaloro, Frank G, Wang, Yongping, Sporn, Michael B

“…We initially randomly synthesized about 60 oleanane and ursane triterpenoids as potential anti-inflammatory and cancer chemopreventive agents. Preliminary…”
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Kinetic versus Thermodynamic Control in the Dehydration of 2-Methylcyclopentanol: A Two-Part Laboratory Experiment Utilizing the Gignard Reaction and GC-MS by Poon, Thomas, Mundy, Bradford P, McIntyre, Jean, Woods, Lesley, Favaloro, Frank G, Goudreau, Christina A

“…A two part organic laboratory experiment illustrating the Grignard reaction and the concept of kinetic versus thermodynamic control is described. The reaction…”
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Tricyclic Compounds Containing Non-enolizable Cyano Enones. A Novel Class of Highly Potent Anti-inflammatory and Cytoprotective Agents by Honda, Tadashi, Yoshizawa, Hidenori, Sundararajan, Chitra, David, Emilie, Lajoie, Marc J., Favaloro, Frank G., Janosik, Tomasz, Su, Xiaobo, Honda, Yukiko, Roebuck, Bill D., Gribble, Gordon W.

“…Forty-four novel tricycles containing non-enolizable cyano enones (TCEs) were designed and synthesized on the basis of a semisynthetic pentacyclic…”
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Novel synthetic oleanane triterpenoids: A series of highly active inhibitors of nitric oxide production in mouse macrophages by Honda, Ta-i, Rounds, BarbieAnn V., Bore, Lothar, Favaloro, Frank G., Gribble, Gordon W., Suh, Nanjoo, Wang, Yongping, Sporn, Michael B.

“…Novel oleanane triterpenoids with modified rings A and C were designed and synthesized. Among them, methyl 2-carboxy-3,12-dioxooleana-1,9-dien-28-oate showed…”
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NATURAL PRODUCTS VIA REETZ CHEMISTRY SYNTHESIS OF (±)-CUPARENE by Favaloro, Frank G., Goudreau, Christina A., Mundy, Bradford P., Poon, Thomas, Slobodzian, Sergei V., Jensen, Bruce L.

“…A concise synthesis of (±)-cuparene via Grignard, trimethylaluminum and dimethyltitanium dichloride (Reetz Alkylation) reactions to form the quaternary centers…”
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