Search Results - "Fava, Maurizio"

Implications of a Biosignature Study of the Placebo Response in Major Depressive Disorder by Fava, Maurizio

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Diagnosis and definition of treatment-resistant depression by Fava, Maurizio

“…Treatment-resistant depression (TRD) typically refers to inadequate response to at least one antidepressant trial of adequate doses and duration. TRD is a…”
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Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD) by Fava, Maurizio, Freeman, Marlene P., Flynn, Martina, Judge, Heidi, Hoeppner, Bettina B., Cusin, Cristina, Ionescu, Dawn F., Mathew, Sanjay J., Chang, Lee C., Iosifescu, Dan V., Murrough, James, Debattista, Charles, Schatzberg, Alan F., Trivedi, Madhukar H., Jha, Manish K, Sanacora, Gerard, Wilkinson, Samuel T., Papakostas, George I.

“…Numerous placebo-controlled studies have demonstrated the ability of ketamine, an NMDA receptor antagonist, to induce rapid (within hours), transient…”
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Harmonization of cortical thickness measurements across scanners and sites by Fortin, Jean-Philippe, Cullen, Nicholas, Sheline, Yvette I., Taylor, Warren D., Aselcioglu, Irem, Cook, Philip A., Adams, Phil, Cooper, Crystal, Fava, Maurizio, McGrath, Patrick J., McInnis, Melvin, Phillips, Mary L., Trivedi, Madhukar H., Weissman, Myrna M., Shinohara, Russell T.

“…With the proliferation of multi-site neuroimaging studies, there is a greater need for handling non-biological variance introduced by differences in MRI…”
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Statistical harmonization corrects site effects in functional connectivity measurements from multi‐site fMRI data by Yu, Meichen, Linn, Kristin A., Cook, Philip A., Phillips, Mary L., McInnis, Melvin, Fava, Maurizio, Trivedi, Madhukar H., Weissman, Myrna M., Shinohara, Russell T., Sheline, Yvette I.

“…Acquiring resting‐state functional magnetic resonance imaging (fMRI) datasets at multiple MRI scanners and clinical sites can improve statistical power and…”
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Success and efficiency of phase 2/3 adjunctive trials for MDD funded by industry: a systematic review by Salloum, Naji C., Fava, Maurizio, Ball, Sophia, Papakostas, George I.

“…To review the success rate and efficiency of industry-sponsored phase 2/3 clinical trials for adjunctive therapies for antidepressant partial- and…”
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An electroencephalographic signature predicts antidepressant response in major depression by Wu, Wei, Zhang, Yu, Jiang, Jing, Lucas, Molly V., Fonzo, Gregory A., Rolle, Camarin E., Cooper, Crystal, Chin-Fatt, Cherise, Krepel, Noralie, Cornelssen, Carena A., Wright, Rachael, Toll, Russell T., Trivedi, Hersh M., Monuszko, Karen, Caudle, Trevor L., Sarhadi, Kamron, Jha, Manish K., Trombello, Joseph M., Deckersbach, Thilo, Adams, Phil, McGrath, Patrick J., Weissman, Myrna M., Fava, Maurizio, Pizzagalli, Diego A., Arns, Martijn, Trivedi, Madhukar H., Etkin, Amit

“…Antidepressants are widely prescribed, but their efficacy relative to placebo is modest, in part because the clinical diagnosis of major depression encompasses…”
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Does the probability of receiving placebo influence clinical trial outcome? A meta-regression of double-blind, randomized clinical trials in MDD by Papakostas, George I, Fava, Maurizio

“…Abstract Substantial and highly variable placebo response rates represent a major obstacle to antidepressant development in major depressive disorder (MDD)…”
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REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial by Fava, Maurizio, Stahl, Stephen, Pani, Luca, De Martin, Sara, Pappagallo, Marco, Guidetti, Clotilde, Alimonti, Andrea, Bettini, Ezio, Mangano, Richard M, Wessel, Thomas, de Somer, Marc, Caron, Judy, Vitolo, Ottavio V, DiGuglielmo, Gina R, Gilbert, Adam, Mehta, Hiren, Kearney, Morgan, Mattarei, Andrea, Gentilucci, Marco, Folli, Franco, Traversa, Sergio, Inturrisi, Charles E, Manfredi, Paolo L

“…The purpose of this study was to examine the effects of REL-1017 (esmethadone), a novel -methyl-d-aspartate receptor (NMDAR) channel blocker, in patients with…”
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A Brief Review on the Potential of Psychedelics for Treating Alzheimer's Disease and Related Depression by Pilozzi, Alexander, Foster, Simmie, Mischoulon, David, Fava, Maurizio, Huang, Xudong

“…Alzheimer's disease (AD), the most common form of senile dementia, is poised to place an even greater societal and healthcare burden as the population ages…”
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Childhood trauma history is linked to abnormal brain connectivity in major depression by Yu, Meichen, Linn, Kristin A., Shinohara, Russell T., Oathes, Desmond J., Cook, Philip A., Duprat, Romain, Moore, Tyler M., Oquendo, Maria A., Phillips, Mary L., McInnis, Melvin, Fava, Maurizio, Trivedi, Madhukar H., McGrath, Patrick, Parsey, Ramin, Weissman, Myrna M., Sheline, Yvette I.

“…Patients with major depressive disorder (MDD) present with heterogeneous symptom profiles, while neurobiological mechanisms are still largely unknown. Brain…”
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Illness Progression, Recent Stress, and Morphometry of Hippocampal Subfields and Medial Prefrontal Cortex in Major Depression by Treadway, Michael T, Waskom, Michael L, Dillon, Daniel G, Holmes, Avram J, Park, Min Tae M, Chakravarty, M. Mallar, Dutra, Sunny J, Polli, Frida E, Iosifescu, Dan V, Fava, Maurizio, Gabrieli, John D.E, Pizzagalli, Diego A

“…Abstract Background Longitudinal studies of illness progression in patients with major depressive disorder (MDD) indicate that the onset of subsequent…”
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Amyotrophic lateral sclerosis disease progression model by Gomeni, Roberto, Fava, Maurizio

“…Abstract Our objective was to develop: 1) a longitudinal model to describe amyotrophic lateral sclerosis (ALS) disease progression using the revised…”
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Opioid system modulation with buprenorphine/samidorphan combination for major depressive disorder: two randomized controlled studies by Fava, Maurizio, Thase, Michael E., Trivedi, Madhukar H., Ehrich, Elliot, Martin, William F., Memisoglu, Asli, Nangia, Narinder, Stanford, Arielle D., Yu, Miao, Pathak, Sanjeev

“…The endogenous opioid system is thought to play an important role in the regulation of mood. Buprenorphine/samidorphan (BUP/SAM) combination is an…”
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Reduced hedonic capacity in major depressive disorder: Evidence from a probabilistic reward task by Pizzagalli, Diego A, Iosifescu, Dan, Hallett, Lindsay A, Ratner, Kyle G, Fava, Maurizio

“…Abstract Objective Anhedonia, the lack of reactivity to pleasurable stimuli, is a cardinal feature of depression that has received renewed interest as a…”
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Treatment of SSRI-Resistant Depression: A Meta-Analysis Comparing Within- Versus Across-Class Switches by Papakostas, George I, Fava, Maurizio, Thase, Michael E

“…Background Two broad treatment options exist for switching antidepressants for depressed patients who fail to respond to a selective serotonin reuptake…”
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The STARD Project results: a comprehensive review of findings by Warden, Diane, Rush, A John, Trivedi, Madhukar H, Fava, Maurizio, Wisniewski, Stephen R

“…The Sequenced Treatment Alternatives to Relieve Depression trial enrolled outpatients with nonpsychotic major depressive disorder treated prospectively in a…”
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Artificial intelligence approach for the analysis of placebo-controlled clinical trials in major depressive disorders accounting for individual propensity to respond to placebo by Gomeni, Roberto, Bressolle-Gomeni, Françoise, Fava, Maurizio

“…Treatment effect in clinical trials for major depressive disorders (RCT) can be viewed as the resultant of treatment specific and non-specific effects…”
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Test-retest reliability of freesurfer measurements within and between sites: Effects of visual approval process by Iscan, Zafer, Jin, Tony B., Kendrick, Alexandria, Szeglin, Bryan, Lu, Hanzhang, Trivedi, Madhukar, Fava, Maurizio, McGrath, Patrick J., Weissman, Myrna, Kurian, Benji T., Adams, Phillip, Weyandt, Sarah, Toups, Marisa, Carmody, Thomas, McInnis, Melvin, Cusin, Cristina, Cooper, Crystal, Oquendo, Maria A., Parsey, Ramin V., DeLorenzo, Christine

“…In the last decade, many studies have used automated processes to analyze magnetic resonance imaging (MRI) data such as cortical thickness, which is one…”
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Poor sleep quality and suicide attempt among adults with internet addiction: A nationwide community sample of Korea by Kim, Kiwon, Lee, Haewoo, Hong, Jin Pyo, Cho, Maeng Je, Fava, Maurizio, Mischoulon, David, Kim, Dong Jun, Jeon, Hong Jin

“…Internet addiction (IA) is defined as a psychological dependence on the internet, regardless of the type of activities once logged on, and previous studies…”
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