Search Results - "Fava, Marika"
-
1
Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling
Published in Arteriosclerosis, thrombosis, and vascular biology (01-07-2018)“…OBJECTIVE—Thoracic aortic aneurysm (TAA), a degenerative disease of the aortic wall, is accompanied by changes in the structure and composition of the aortic…”
Get full text
Journal Article -
2
Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries
Published in Circulation (New York, N.Y.) (09-01-2018)“…BACKGROUND:Extracellular matrix (ECM) remodeling contributes to in-stent restenosis and thrombosis. Despite its important clinical implications, little is…”
Get full text
Journal Article -
3
Role of miR-195 in Aortic Aneurysmal Disease
Published in Circulation research (24-10-2014)“…RATIONALE:Abdominal aortic aneurysms constitute a degenerative process in the aortic wall. Both the miR-29 and miR-15 families have been implicated in…”
Get full text
Journal Article -
4
Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2019)“…OBJECTIVE:Marfan syndrome (MFS) is caused by mutations in FBN1 (fibrillin-1), an extracellular matrix (ECM) component, which is modified post-translationally…”
Get full text
Journal Article -
5
Glycoproteomics of the Extracellular Matrix: A Method for Intact Glycopeptide Analysis Using Mass Spectrometry
Published in Journal of visualized experiments (21-04-2017)“…Fibrosis is a hallmark of many cardiovascular diseases and is associated with the exacerbated secretion and deposition of the extracellular matrix (ECM). Using…”
Get full text
Journal Article -
6
Myocardial Matrix Hydrogels for Cardiac Repair: The Devil Is in the Details
Published in JACC. Basic to translational science (01-03-2024)“…[Display omitted]…”
Get full text
Journal Article -
7
Myocardial Matrix Hydrogels for Cardiac Repair
Published in JACC. Basic to translational science (01-03-2024)Get full text
Journal Article -
8
Proteomics of the epicardial fat secretome and its role in post-operative atrial fibrillation
Published in Europace (London, England) (01-07-2018)“…Post-operative atrial fibrillation (POAF) is a predictor of morbidity and mortality after cardiac surgery. Latent predisposing factors may reside in the…”
Get full text
Journal Article -
9
Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modelling a European cardiomyopathy with global impact
Published in Cardiovascular research (09-12-2022)“…A mutation in the phospholamban (PLN) gene, leading to deletion of Arg14 (R14del), has been associated with malignant arrhythmias and ventricular dilation…”
Get full text
Journal Article -
10
Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling
Published in Circulation (New York, N.Y.) (21-12-2021)“…Remodeling of the extracellular matrix (ECM) is a hallmark of heart failure (HF). Our previous analysis of the secretome of murine cardiac fibroblasts returned…”
Get full text
Journal Article -
11
Locally different proteome in aortas from patients with stenotic tricuspid and bicuspid aortic valves
Published in European journal of cardio-thoracic surgery (01-09-2019)“…We aimed to compare the intracellular proteome of ascending aortas from patients with stenotic bicuspid (BAV) and tricuspid aortic valves (TAV) to identify…”
Get full text
Journal Article -
12
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins
Published in Cardiovascular research (01-06-2016)“…Extracellular matrix remodelling has been implicated in a number of vascular conditions, including venous hypertension and varicose veins. However, to date, no…”
Get full text
Journal Article -
13
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation
Published in Circulation (New York, N.Y.) (13-09-2016)“…BACKGROUND:Myocardial fibrosis is a feature of many cardiac diseases. We used proteomics to profile glycoproteins in the human cardiac extracellular matrix…”
Get full text
Journal Article -
14
Proteoglycan remodelling in aortic stenosis
Published in Journal of molecular and cellular cardiology (31-12-2022)Get full text
Journal Article -
15
The Extracellular Matrix in Heart Failure: The Role of Adamts5 In Proteoglycan Remodelling
Published in Circulation (New York, N.Y.) (21-12-2021)Get full text
Journal Article -
16
Abstract 311: The Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2018)“…Abstract only Thoracic aortic aneurysm (TAA), a degenerative disease of the aortic wall, is accompanied by changes in the structure and composition of the…”
Get full text
Journal Article -
17
Glycoproteomics of the Extracellular Matrix: A Method for Intact Glycopeptide Analysis Using Mass Spectrometry
Published in Journal of visualized experiments (21-04-2017)Get full text
Journal Article -
18
Integrative gene regulatory network analysis discloses key driver genes of fibromuscular dysplasia
Published in Nature cardiovascular research (01-09-2024)“…Fibromuscular dysplasia (FMD) is a poorly understood disease affecting 3-5% of adult females. The pathobiology of FMD involves arterial lesions of stenosis,…”
Get more information
Journal Article -
19
Abstract 15036: Role of miR-195 in Aneurysm Formation
Published in Circulation (New York, N.Y.) (25-11-2014)“…Abstract only Introduction: Abdominal aortic aneurysm (AAA) is a degenerative disease of the aorta. Apart from the miR-29 family, miR-195 has been implicated…”
Get full text
Journal Article