Search Results - "Fauvet, Frédérique"

Combined nanomedicines targeting colorectal cancer stem cells and cancer cells by Tsakiris, Nikolaos, Fauvet, Frédérique, Ruby, Samia, Puisieux, Alain, Paquot, Adrien, Muccioli, Giulio G., Vigneron, Arnaud M., Préat, Véronique

“…The study aims to combine the delivery of two anticancer drugs to target both proliferating cancer cells and dormant cancer stem cells (CSCs) present in…”
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Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence by Ansieau, Stéphane, Bastid, Jeremy, Doreau, Agnès, Morel, Anne-Pierre, Bouchet, Benjamin P., Thomas, Clémence, Fauvet, Frédérique, Puisieux, Isabelle, Doglioni, Claudio, Piccinin, Sara, Maestro, Roberta, Voeltzel, Thibault, Selmi, Abdelkader, Valsesia-Wittmann, Sandrine, Caron de Fromentel, Claude, Puisieux, Alain

“…Twist1 and Twist2 are major regulators of embryogenesis. Twist1 has been shown to favor the metastatic dissemination of cancer cells through its ability to…”
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p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose by Huber, Anne-Laure, Lebeau, Justine, Guillaumot, Patricia, Pétrilli, Virginie, Malek, Mouhannad, Chilloux, Julien, Fauvet, Frédérique, Payen, Léa, Kfoury, Alain, Renno, Toufic, Chevet, Eric, Manié, Serge N

“…As solid tumors expand, oxygen and nutrients become limiting owing to inadequate vascularization and diffusion. How malignant cells cope with this potentially…”
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EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice by Morel, Anne-Pierre, Hinkal, George W, Thomas, Clémence, Fauvet, Frédérique, Courtois-Cox, Stéphanie, Wierinckx, Anne, Devouassoux-Shisheboran, Mojgan, Treilleux, Isabelle, Tissier, Agnès, Gras, Baptiste, Pourchet, Julie, Puisieux, Isabelle, Browne, Gareth J, Spicer, Douglas B, Lachuer, Joël, Ansieau, Stéphane, Puisieux, Alain

“…The epithelial-mesenchymal transition (EMT) is an embryonic transdifferentiation process consisting of conversion of polarized epithelial cells to motile…”
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Snail family members unequally trigger EMT and thereby differ in their ability to promote the neoplastic transformation of mammary epithelial cells by Gras, Baptiste, Jacqueroud, Laurent, Wierinckx, Anne, Lamblot, Christelle, Fauvet, Frédérique, Lachuer, Joël, Puisieux, Alain, Ansieau, Stéphane

“…By fostering cell commitment to the epithelial-to-mesenchymal transition (EMT), SNAIL proteins endow cells with motility, thereby favoring the metastatic…”
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EMT Transcription Factor ZEB1 Represses the Mutagenic POLθ-Mediated End-Joining Pathway in Breast Cancers by Prodhomme, Mélanie K, Pommier, Roxane M, Franchet, Camille, Fauvet, Frédérique, Bergoglio, Valérie, Brousset, Pierre, Morel, Anne-Pierre, Brunac, Anne-Cécile, Devouassoux-Shisheboran, Mojgan, Petrilli, Virginie, Moyret-Lalle, Caroline, Hoffmann, Jean-Sébastien, Puisieux, Alain, Tissier, Agnès

“…A characteristic of cancer development is the acquisition of genomic instability, which results from the inaccurate repair of DNA damage. Among double-strand…”
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Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer by Ortiz-Cuaran, Sandra, Swalduz, Aurélie, Foy, Jean-Philippe, Marteau, Solène, Morel, Anne-Pierre, Fauvet, Frédérique, De Souza, Geneviève, Michon, Lucas, Boussageon, Maxime, Gadot, Nicolas, Godefroy, Marion, Léon, Sophie, Tortereau, Antonin, Mourksi, Nour-El-Houda, Leonce, Camille, Albaret, Marie Alexandra, Dongre, Anushka, Vanbervliet, Béatrice, Robert, Marie, Tonon, Laurie, Pommier, Roxane M., Hofman, Véronique, Attignon, Valéry, Boyault, Sandrine, Audoynaud, Carole, Auclair, Jessie, Bouquet, Fanny, Wang, Qing, Ménétrier-Caux, Christine, Pérol, Maurice, Caux, Christophe, Hofman, Paul, Lantuejoul, Sylvie, Puisieux, Alain, Saintigny, Pierre

“…Epithelial-to-mesenchymal transition (EMT) is associated with tumor aggressiveness, drug resistance, and poor survival in non-small cell lung cancer (NSCLC)…”
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Cooperative pro-tumorigenic adaptation to oncogenic RAS through epithelial-to-mesenchymal plasticity by De Blander, Hadrien, Tonon, Laurie, Fauvet, Frédérique, Pommier, Roxane M, Lamblot, Christelle, Benhassoun, Rahma, Angileri, Francesca, Gibert, Benjamin, Rodriguez, Raphaël, Ouzounova, Maria, Morel, Anne-Pierre, Puisieux, Alain

“…In breast cancers, aberrant activation of the RAS/MAPK pathway is strongly associated with mesenchymal features and stemness traits, suggesting an interplay…”
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Assessing Cell Activities rather than Identities to Interpret Intra-Tumor Phenotypic Diversity and Its Dynamics by Monteiro, Laloé, Da Silva, Lydie, Lipinski, Boris, Fauvet, Frédérique, Vigneron, Arnaud, Puisieux, Alain, Martinez, Pierre

“…Despite advances in single-cell and molecular techniques, it is still unclear how to best quantify phenotypic heterogeneity in cancer cells that evolved beyond…”
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A stemness-related ZEB1–MSRB3 axis governs cellular pliancy and breast cancer genome stability by Morel, Anne-Pierre, Ginestier, Christophe, Pommier, Roxane M, Cabaud, Olivier, Ruiz, Emmanuelle, Wicinski, Julien, Devouassoux-Shisheboran, Mojgan, Combaret, Valérie, Finetti, Pascal, Chassot, Christelle, Pinatel, Christiane, Fauvet, Frédérique, Saintigny, Pierre, Thomas, Emilie, Moyret-Lalle, Caroline, Lachuer, Joël, Despras, Emmanuelle, Jauffret, Jean-Luc, Bertucci, François, Guitton, Jérôme, Wierinckx, Anne, Wang, Qing, Radosevic-Robin, Nina, Penault-Llorca, Frédérique, Cox, David G, Hollande, Frédéric, Ansieau, Stéphane, Caramel, Julie, Birnbaum, Daniel, Vigneron, Arnaud M, Tissier, Agnès, Charafe-Jauffret, Emmanuelle, Puisieux, Alain

“…During malignant transformation, the ability of mammary epithelial cells to cope with oncogene-induced DNA damage and avoid chromosomal instability is…”
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p21(Cip1) regulates cell-substrate adhesion and interphase microtubule dynamics in untransformed human mammary epithelial cells by Bouchet, Benjamin Pierre, Fauvet, Frédérique, Grelier, Gaël, Galmarini, Carlos María, Puisieux, Alain

“…Despite its frequent inactivation in human breast cancers, the role of p21(Cip1) (p21) in morphological plasticity of normal mammary epithelial cells is still…”
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p58IPK-Mediated Attenuation of the Proapoptotic PERK-CHOP Pathway Allows Malignant Progression upon Low Glucose by Huber, Anne-Laure, Lebeau, Justine, Guillaumot, Patricia, Pétrilli, Virginie, Malek, Mouhannad, Chilloux, Julien, Fauvet, Frédérique, Payen, Léa, Kfoury, Alain, Renno, Toufic, Chevet, Eric, Manié, Serge N.

“…As solid tumors expand, oxygen and nutrients become limiting owing to inadequate vascularization and diffusion. How malignant cells cope with this potentially…”
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p21 Cip1 regulates cell–substrate adhesion and interphase microtubule dynamics in untransformed human mammary epithelial cells by Bouchet, Benjamin Pierre, Fauvet, Frédérique, Grelier, Gaël, Galmarini, Carlos María, Puisieux, Alain

“…Despite its frequent inactivation in human breast cancers, the role of p21 Cip1 (p21) in morphological plasticity of normal mammary epithelial cells is still…”
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Abstract 2667: RAS-induced transformation of mammary epithelial cells relies upon a ZEB1-dependent cellular reprogramming through a paracrine process by PUISIEUX, ALAIN, De Blander, Hadrien, Tonon, Laurie, Fauvet, Frédérique, Pommier, Roxane, Lamblot, Christelle, Benhassoun, Rahma, Gibert, Benjamin, Ouzounova, Maria, Morel, Anne-Pierre

“…Abstract Despite an enhanced interest, the origin of cancer stem cells (CSCs) remains equivocal. A strong body of evidence suggests that, in some adult…”
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p21Cip1 regulates cell–substrate adhesion and interphase microtubule dynamics in untransformed human mammary epithelial cells by Bouchet, Benjamin Pierre, Fauvet, Frédérique, Grelier, Gaël, Galmarini, Carlos María, Puisieux, Alain

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Abstract 4813: EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors by Morel, Anne-Pierre, Thomas, Clémence, Hinkal, George, Fauvet, Frederique, Courtois-Cox, Stephanie, Wierinckx, Anne, Devouassoux-Shisheboran, Mojgan, Tissier, Agnes, GRAS, Baptiste, Pourchet, Julie, Puisieux, Isabelle, Browne, Gareth, Spicer, Douglas B., Lachuer, Joel, Ansieau, Stephane, Puisieux, Alain

“…Abstract The malignant transformation of human epithelial cells is generally described as a multistep process resulting from the accumulation of five to seven…”
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