Search Results - "Faust Akl, Camilo"
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1
Glial and myeloid heterogeneity in the brain tumour microenvironment
Published in Nature reviews. Cancer (01-12-2021)“…Brain cancers carry bleak prognoses, with therapeutic advances helping only a minority of patients over the past decade. The brain tumour microenvironment…”
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2
Astrocyte control of brain metastasis
Published in Developmental cell (11-03-2024)“…Developing therapeutics to improve metastatic brain cancer prognosis is hampered by limited experimental systems that recapitulate the brain tumor…”
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3
Identification of environmental factors that promote intestinal inflammation
Published in Nature (London) (24-11-2022)“…Genome-wide association studies have identified risk loci linked to inflammatory bowel disease (IBD) 1 —a complex chronic inflammatory disorder of the…”
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4
Droplet-based functional CRISPR screening of cell-cell interactions by SPEAC-seq
Published in Nature protocols (26-09-2024)“…Cell-cell interactions are essential for the function and contextual regulation of biological tissues. We present a platform for high-throughput…”
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5
Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells
Published in Nature (London) (24-08-2023)“…Dendritic cells (DCs) have a role in the development and activation of self-reactive pathogenic T cells 1 , 2 . Genetic variants that are associated with the…”
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Droplet-based forward genetic screening of astrocyte-microglia cross-talk
Published in Science (American Association for the Advancement of Science) (10-03-2023)“…Cell-cell interactions in the central nervous system play important roles in neurologic diseases. However, little is known about the specific molecular…”
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7
Identification of astrocyte regulators by nucleic acid cytometry
Published in Nature (London) (09-02-2023)“…Multiple sclerosis is a chronic inflammatory disease of the central nervous system 1 . Astrocytes are heterogeneous glial cells that are resident in the…”
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Disease-associated astrocyte epigenetic memory promotes CNS pathology
Published in Nature (London) (28-03-2024)“…Disease-associated astrocyte subsets contribute to the pathology of neurologic diseases, including multiple sclerosis and experimental autoimmune…”
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Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology
Published in Nature (London) (11-07-2024)Get full text
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10
Examination of Brain Tumor-Associated Astrocytes at Single-Cell Resolution
Published 01-01-2021“…Astrocytes are multifunctional cells of the central nervous system (CNS), are intimately linked into the immune modulatory processes that govern homeostasis…”
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Dissertation