Search Results - "Faust, Jurgen"

Dual Inhibition of Dipeptidyl Peptidase IV and Aminopeptidase N Suppresses Inflammatory Immune Responses by REINHOLD, DIRK, BITON, ALIZA, GOIHL, ALEXANDER, PIEPER, STEFANIE, LENDECKEL, UWE, FAUST, JÜRGEN, NEUBERT, KLAUS, BANK, UTE, TÄGER, MICHAEL, ANSORGE, SIEGFRIED, BROCKE, STEFAN

“…:  The ectopeptidases dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) are known to regulate T cell activation. Since selective…”
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TGF-β1-Mediated Control of Central Nervous System Inflammation and Autoimmunity through the Inhibitory Receptor CD26 by Preller, Vera, Gerber, Annegret, Wrenger, Sabine, Togni, Mauro, Marguet, Didier, Tadje, Janine, Lendeckel, Uwe, Röcken, Christoph, Faust, Jürgen, Neubert, Klaus, Schraven, Burkhart, Martin, Roland, Ansorge, Siegfried, Brocke, Stefan, Reinhold, Dirk

“…The T cell marker CD26/dipeptidyl peptidase (DP) IV is associated with an effector phenotype and markedly elevated in the human CNS disorder multiple…”
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Transcellular Proteolysis Demonstrated by Novel Cell Surface-associated Substrates of Dipeptidyl Peptidase IV (CD26) by Lorey, Susan, Faust, Ju¨rgen, Mrestani-Klaus, Carmen, Ka¨hne, Thilo, Ansorge, Siegfried, Neubert, Klaus, Bu¨hling, Frank

“…Proteolytic enzymes contribute to the regulation of cellular functions such as cell proliferation and death, cytokine production, and matrix remodeling…”
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Inhibitors of Dipeptidyl Peptidase IV-Like Activity Mediate Antifibrotic Effects in Normal and Keloid-Derived Skin Fibroblasts by Thielitz, Anja, Vetter, Robert W., Schultze, Bianca, Wrenger, Sabine, Simeoni, Luca, Ansorge, Siegfried, Neubert, Klaus, Faust, Jürgen, Lindenlaub, Petra, Gollnick, Harald P.M., Reinhold, Dirk

“…Suppression of collagen and matrix synthesis and inhibition of the fibrogenic cytokine transforming growth factor-β1 (TGF-β1) is a major therapeutic goal in…”
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DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis by Reinhold, Dirk, Bank, Ute, Täger, Michael, Ansorge, Siegfried, Wrenger, Sabine, Thielitz, Anja, Lendeckel, Uwe, Faust, Jürgen, Neubert, Klaus, Brocke, Stefan

“…Multiple sclerosis (MS) is the most frequent demyelinating disease of the central nervous system. Peptidases like dipeptidyl peptidase IV (DP IV, CD26) and…”
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Inhibitors of Dipeptidyl Peptidase IV and Aminopeptidase N Target Major Pathogenetic Steps in Acne Initiation by Thielitz, Anja, Reinhold, Dirk, Vetter, Robert, Bank, Ute, Helmuth, Martin, Hartig, Roland, Wrenger, Sabine, Wiswedel, Ingrid, Lendeckel, Uwe, Kähne, Thilo, Neubert, Klaus, Faust, Jürgen, Zouboulis, Christos C., Ansorge, Siegfried, Gollnick, Harald

“…Acne is a chronic disease hallmarked by sebaceous hyperplasia, follicular hyperkeratosis, and inflammation. Parallel targeting of these factors is required to…”
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Hofmeister Salts and Potential Therapeutic Compounds Accelerate in Vitro Fibril Formation of the N-Terminal Domain of PABPN1 Containing a Disease-Causing Alanine Extension by Lodderstedt, Grit, Sachs, Rolf, Faust, Jürgen, Bordusa, Frank, Kühn, Uwe, Golbik, Ralph, Kerth, Andreas, Wahle, Elmar, Balbach, Jochen, Schwarz, Elisabeth

“…The analysis of modulation of fibril formation helps to understand the mechanism of fibrillation processes besides opening routes for therapeutic intervention…”
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Designing design and designing media by Faust, Jurgen

“…When we reframe design through a discourse, designing on a meta level, we are actually designing design, as we are giving design a different meaning, changing…”
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Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function by Wrenger, Sabine, Faust, Jürgen, Friedrich, Daniel, Hoffmann, Torsten, Hartig, Roland, Lendeckel, Uwe, Kähne, Thilo, Thielitz, Anja, Neubert, Klaus, Reinhold, Dirk

“…The ectoenzyme dipeptidyl peptidase IV (DP IV; CD26) was shown to play a crucial role in T cell activation. Several compounds inhibiting DP IV‐like activity…”
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Hofmeister Salts and Potential Therapeutic Compounds Accelerate in Vitro Fibril Formation of the N-Terminal Domain of PABPN1 Containing a Disease-Causing Alanine Extension by Lodderstedt, Grit, Sachs, Rolf, Faust, Jürgen, Bordusa, Frank, Kühn, Uwe, Golbik, Ralph, Kerth, Andreas, Wahle, Elmar, Balbach, Jochen, Schwarz, Elisabeth

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TGF-beta1-Mediated Control of Central Nervous System Inflammation and Autoimmunity through the Inhibitory Receptor CD26 by Preller, Vera, Gerber, Annegret, Wrenger, Sabine, Togni, Mauro, Marguet, Didier, Tadje, Janine, Lendeckel, Uwe, Rocken, Christoph, Faust, Jurgen, Neubert, Klaus, Schraven, Burkhart, Martin, Roland, Ansorge, Siegfried, Brocke, Stefan, Reinhold, Dirk

“…The T cell marker CD26/dipeptidyl peptidase (DP) IV is associated with an effector phenotype and markedly elevated in the human CNS disorder multiple…”
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Positive design by Faust, Jurgen

“…This article is focused on the changes needed in design to create positive solutions for all involved in design processes. It draws upon the rich discussion…”
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Non-substrate peptides influencing dipeptidyl peptidase IV/CD26 activity and immune cell function by Wrenger, Sabine, Faust, Jurgen, Mrestani-Klaus, Carmen, Brandt, Wolfgang, Thielitz, Anja, Neubert, Klaus, Reinhold, Dirk

“…Investigations using inhibitors of dipeptidyl peptidase IV (DP IV) activities and DP IV-/- mice indicated an immunoregulatory role of DP IV that could not be…”
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Dipeptidyl peptidase IV (DP IV, CD26) is involved in regulation of DNA synthesis in human keratinocytes by Reinhold, Dirk, Vetter, Robert W, Mnich, Kati, Bühling, Frank, Lendeckel, Uwe, Born, Ilona, Faust, Jürgen, Neubert, Klaus, Gollnick, Harald, Ansorge, Siegfried

“…Various studies have shown that the membrane ectoenzyme dipeptidyl peptidase IV (DP IV, CD26), expressed on T, NK, and B cells in the human immune system, is…”
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Positive Design : DESIGN: INFORMATION TECHNOLOGIES AND CREATIVE PRACTICES by FAUST, Jurgen

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Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) specifically suppress proliferation and modulate cytokine production of strongly CD26 expressing U937 cells by Reinhold, D, Bank, U, Bühling, F, Kähne, T, Kunt, D, Faust, J, Neubert, K, Ansorge, S

“…Various studies from different laboratories have shown that the membrane ectoenzyme dipeptidyl peptidase IV (DP IV, CD26) expressed in T and NK cells is…”
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Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions by Ansorge, Siegfried, Bank, Ute, Heimburg, Anke, Helmuth, Martin, Koch, Gudrun, Tadje, Janine, Lendeckel, Uwe, Wolke, Carmen, Neubert, Klaus, Faust, Jürgen, Fuchs, Petra, Reinhold, Dirk, Thielitz, Anja, Täger, Michael

“…In the past, different research groups could show that treatment of immune cells with inhibitors of post-proline splitting dipeptidyl aminopeptidases leads to…”
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Role of dipeptidyl peptidase IV (DP IV)-like enzymes in T lymphocyte activation: investigations in DP IV/CD26-knockout mice by Reinhold, Dirk, Goihl, Alexander, Wrenger, Sabine, Reinhold, Annegret, Kühlmann, Ulrike C, Faust, Jürgen, Neubert, Klaus, Thielitz, Anja, Brocke, Stefan, Täger, Michael, Ansorge, Siegfried, Bank, Ute

“…Dipeptidyl peptidase IV (DP IV, CD26) and DP IV-like enzymes, such as dipeptidyl peptidase II (DP II), dipeptidyl peptidase 8 (DP8), and dipeptidyl peptidase 9…”
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Transcellular proteolysis demonstrated by novel cell surface-associated substrates of dipeptidyl peptidase IV (CD26) by Lorey, Susan, Faust, Jurgen, Mrestani-Klaus, Carmen, Kähne, Thilo, Ansorge, Siegfried, Neubert, Klaus, Bühling, Frank

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1H NMR conformational study on n-terminal nonapeptide sequences of HIV-1 Tat protein: a contribution to structure-activity relationships by Mrestani-Klaus, Carmen, Fengler, Annett, Brandt, Wolfgang, Faust, Jürgen, Wrenger, Sabine, Reinhold, Dirk, Ansorge, Siegfried, Neubert, Klaus

“…On the basis of our recent results, the N‐terminal sequence of HIV‐1 Tat protein as a natural competitive inhibitor of dipeptidyl peptidase IV (DP IV) is…”
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