Search Results - "Faucheux, B. A."

Compassionate use of quinacrine in Creutzfeldt-Jakob disease fails to show significant effects by HAÏK, S, BRANDEL, J. P, HAUW, J. J, ALPEROVITCH, A, SALOMON, D, SAZDOVITCH, V, DELASNERIE-LAUPRETRE, N, LAPLANCHE, J. L, FAUCHEUX, B. A, SOUBRIE, C, BOHER, E, BELORGEY, C

“…Quinacrine has been reported as an antiprion agent and proposed as an immediately applicable treatment for Creutzfeldt-Jakob disease (CJD). The authors report…”
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Preservation of midbrain catecholaminergic neurons in very old human subjects by Kubis, N., Faucheux, B. A., Ransmayr, G., Damier, P., Duyckaerts, C., Henin, D., Forette, B., Le Charpentier, Y., Hauw, J.-J., Agid, Y., Hirsch, E. C.

“…Parkinson's disease is characterized by a progressive degeneration of dopaminergic neurons in the midbrain, yet the cause of this neuronal loss is still…”
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Quantification of surviving cerebellar granule neurones and abnormal prion protein (PrPSc) deposition in sporadic Creutzfeldt-Jakob disease supports a pathogenic role for small PrPSc deposits common to the various molecular subtypes by Faucheux, B. A., Morain, E., Diouron, V., Brandel, J.-P., Salomon, D., Sazdovitch, V., Privat, N., Laplanche, J.-L., Hauw, J.-J., Haïk, S.

“…B. A. Faucheux, E. Morain, V. Diouron, J.‐P. Brandel, D. Salomon, V. Sazdovitch, N. Privat, J.‐L. Laplanche, J.‐J. Hauw and S. Haïk (2011) Neuropathology and…”
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FADD: A link between TNF family receptors and caspases in Parkinson's disease by HARTMANN, A, MOUATT-PRIGENT, A, FAUCHEUX, B. A, AGID, Y, HIRSCH, E. C

“…Fas-associating protein with a death domain (FADD) is a proximal adaptor protein of the tumor necrosis factor (TNF) receptor family death pathway. This human…”
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Blood vessels change in the mesencephalon of patients with Parkinson's disease by Faucheux, Baptiste A, Agid, Yves, Hirsch, Etienne C, Bonnet, Anne-Marie

“…The authors compared in a study the numbers of nuclei of blood vessel endothelial cells, melanised neurons, non-melanised neurons and glial cells in…”
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Iron metabolism and Parkinson's disease by HIRSCH, E. C, FAUCHEUX, B. A

“…There are at least three major reasons for thinking that iron participates in the mechanism of nerve cell death in Parkinson's disease (PD): (1) Iron catalyzes…”
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Cellular distribution of the iron-binding protein lactotransferrin in the mesencephalon of Parkinson's disease cases by LEVEUGLE, B, FAUCHEUX, B. A, BOURAS, C, NILLESSE, N, SPIK, G, HIRSCH, E. C, AGIG, Y, HOF, P. R

“…Changes in the distribution of the iron-binding protein lactotransferrin have recently been described in the central nervous system during a variety of…”
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Expression of Lactoferrin Receptors is Increased in the Mesencephalon of Patients with Parkinson Disease by Faucheux, Baptiste A., Nillesse, Nathalie, Damier, Philippe, Spik, Genevieve, Mouatt-Prigent, Annick, Pierce, Annick, Leveugle, Beatrice, Kubis, Nathalie, Hauw, Jean-Jacques, Agid, Yves, Hirsch, Etienne C.

“…The degeneration of nigral dopaminergic neurons in Parkinson disease is believed to be associated with oxidative stress. Since iron levels are increased in the…”
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Caspase-3: A Vulnerability Factor and Final Effector in Apoptotic Death of Dopaminergic Neurons in Parkinson's Disease by Hartmann, A, Hunot, S, Michel, P P, Muriel, M P, Vyas, S, Faucheux, B A, Mouatt-Prigent, A, Turmel, H, Srinivasan, A, Ruberg, M, Evan, G I, Agid, Y, Hirsch, E C

“…Caspase-3 is an effector of apoptosis in experimental models of Parkinson's disease (PD). However, its potential role in the human pathology remains to be…”
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Regional distribution of monoamine vesicular uptake sites in the mesencephalon of control subjects and patients with Parkinson's disease: a postmortem study using tritiated tetrabenazine by Thibaut, F., Faucheux, B.A., Marquez, J., Villares, J., Menard, J.F., Agid, Y., Hirsch, E.C.

“…The distribution of the vesicular monoamine transporter was investigated post mortem in the human ventral mesencephalon of control subjects ( n = 7) and…”
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Autoradiographic localization and density of [ 125I]ferrotransferrin binding sites in the basal ganglia of control subjects, patients with Parkinson's disease and MPTP-lesioned monkeys by Faucheux, B.A., Herrero, M.T., Villares, J., Levy, R., Javoy-Agid, F., Obeso, J.A., Hauw, J.J., Agid, Y., Hirsch, E.C.

“…Degeneration of the nigro-striatal dopaminergic neurons occuring in Parkinson's disease is associated with an increase in iron concentrations in the substantia…”
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Caspase-8 Is an Effector in Apoptotic Death of Dopaminergic Neurons in Parkinson's Disease, But Pathway Inhibition Results in Neuronal Necrosis by Hartmann, Andreas, Troadec, Jean-Denis, Hunot, Stephane, Kikly, Kristy, Faucheux, Baptiste A, Mouatt-Prigent, Annick, Ruberg, Merle, Agid, Yves, Hirsch, Etienne C

“…Caspase-8 is a proximal effector protein of the tumor necrosis factor receptor family death pathway. In the present human postmortem study, we observed a…”
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Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease? by Hartmann, Andreas, Michel, Patrick P., Troadec, Jean‐Denis, Mouatt‐Prigent, Annick, Faucheux, Baptiste A., Ruberg, Merle, Agid, Yves, Hirsch, Etienne C.

“…Bax is a proapoptotic member of the Bcl‐2 family of proteins. It is believed to exert its action primarily by facilitating the release of cytochrome c from the…”
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Distribution of 125I-ferrotransferrin binding sites in the mesencephalon of control subjects and patients with Parkinson's disease by Faucheux, B A, Hirsch, E C, Villares, J, Selimi, F, Mouatt-Prigent, A, Javoy-Agid, F, Hauw, J J, Agid, Y

“…Iron is abnormally accumulated in the substantia nigra pars compacta of patients with Parkinson's disease (PD). Because neuronal and glial iron uptake seems to…”
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Heart rate and blood pressure reactivity during active coping with a mental task in healthy 18- to 73-year-old subjects by Faucheux, B A, Lille, F, Baulon, A, Landau, J, Dupuis, C, Bourlière, F

“…Alterations with aging in the responses of heart rate (HR) and blood pressure (BP) reactivity were investigated during mild mental stress induced by undergoing…”
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Expression of tachykinin NK2 receptor mRNA in human brain by Bensaid, Mohammed, Faucheux, Baptiste A., Hirsch, Etienne, Agid, Yves, Soubrié, Philippe, Oury-Donat, Florence

“…Tachykinin NK2 receptors have been suggested to play an important role in the central nervous system. This study, using reverse transcription-polymerase chain…”
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Is dopaminergic cell death accompanied by concomitant nerve plasticity? by Anglade, P, Blanchard, V, Raisman-Vozari, R, Faucheux, B A, Herrero, M T, Obeso, J A, Mouatt-Prigent, A, Kastner, A, Strada, O, Javoy-Agid, F, Agid, Y, Hirsch, E C

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The density of [ 125I]-transferrin binding sites on perikarya of melanized neurons of the substantia nigra is decreased in Parkinson's disease by Faucheux, Baptiste A., Hauw, Jean-Jacques, Agid, Yves, Hirsch, Etienne C.

“…The density of [ 125I]-diferric-transferrin binding sites was investigated at the cellular level on melanized neurons located in the mesencephalon of patients…”
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Glial cell localization of acidic fibroblast growth factor-like immunoreactivity in the optic nerve of young adult and aged mammals by Faucheux, B A, Cohen, S Y, Delaère, P, Tourbah, A, Dupuis, C, Hartmann, M P, Jeanny, J C, Hauw, J J, Courtois, Y

“…The number of axons in the optic nerve decreases with age and this degeneration is greater in patients suffering from Alzheimer's disease. Alterations in the…”
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Glial cell participation in the degeneration of dopaminergic neurons in Parkinson's disease by Hirsch, E C, Hunot, S, Damier, P, Brugg, B, Faucheux, B A, Michel, P P, Ruberg, M, Muriel, M P, Mouatt-Prigent, A, Agid, Y

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