Search Results - "Faucher, Jean Francois"
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A machine learning approach to predict daptomycin exposure from two concentrations based on Monte Carlo simulations
Published in Antimicrobial agents and chemotherapy (02-05-2024)“…Daptomycin is a concentration-dependent lipopeptide antibiotic for which exposure/effect relationships have been shown. Machine learning (ML) algorithms,…”
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One year of SARS-CoV-2 circulation in the Nouvelle-Aquitaine region, February 2021-2022, France
Published in Frontiers in microbiology (28-07-2023)“…Since 2021, 3 variants of concern (VOC) have spread to France, causing successive epidemic waves. To describe the features of Alpha, Delta and Omicron VOC…”
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Epidemiology of Lyme Borreliosis in France in Primary Care and Hospital Settings, 2010-2019
Published in Vector borne and zoonotic diseases (Larchmont, N.Y.) (01-04-2023)“…Lyme borreliosis (LB) is a growing public health concern requiring accurate and comprehensive epidemiological knowledge to inform health care interventions…”
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Monocytes, particularly nonclassical ones, lose their opsonic and nonopsonic phagocytosis capacity during pediatric cerebral malaria
Published in Frontiers in immunology (21-05-2024)“…Innate immunity is crucial to reducing parasite burden and contributing to survival in severe malaria. Monocytes are key actors in the innate response and,…”
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Plasmodium falciparum Polymorphisms Associated with Ex Vivo Drug Susceptibility and Clinical Effectiveness of Artemisinin-Based Combination Therapies in Benin
Published in Antimicrobial Agents and Chemotherapy (01-01-2014)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria
Published in Malaria journal (07-09-2009)“…An assessment of the accuracy of two malaria rapid diagnostic tests (RDT) for the detection of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) or Pf…”
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High Mortality and Graft Loss after Infective Endocarditis in Kidney Transplant Recipients: A Case-Controlled Study from Two Centers
Published in Pathogens (Basel) (13-08-2021)“…Kidney transplant recipients (KTRs) tend to develop infections with characteristic epidemiology, presentation, and outcome. While infective endocarditis (IE)…”
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Brill-Zinsser disease in Moroccan man, France, 2011
Published in Emerging infectious diseases (01-01-2012)Get full text
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Primaquine for radical cure of Plasmodium vivax and Plasmodium ovale malaria: an observational survey (2008-2010)
Published in Journal of travel medicine (01-03-2013)“…Since 2008, the French guidelines have promoted the systematic use of 30 mg/day of primaquine for the radical cure of Plasmodium vivax and Plamodium ovale…”
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Can treatment of malaria be restricted to parasitologically confirmed malaria? A school-based study in Benin in children with and without fever
Published in Malaria journal (21-04-2010)“…Applying the switch from presumptive treatment of malaria to new policies of anti-malarial prescriptions restricted to parasitologically-confirmed cases is a…”
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What would PCR assessment change in the management of fevers in a malaria endemic area? A school-based study in Benin in children with and without fever
Published in Malaria journal (06-08-2010)“…A recent school-based study in Benin showed that applying a policy of anti-malarial prescriptions restricted to parasitologically-confirmed cases on the…”
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In Silico Pharmacokinetics Evaluation of Forgiveness for Doravirine and Rilpivirine
Published in Therapeutic drug monitoring (01-06-2024)“…This study aimed to evaluate the concentrations of rilpivirine (RLP) and doravirine (DOR) after 3 days-off using simulations from population pharmacokinetics…”
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Doravirine Exposure Decreased by Dialysis in a HIV Patient: A Grand Round
Published in Therapeutic drug monitoring (01-04-2023)“…The authors report the case of a 66-year-old male patient who was hemodialyzed 3 times per week for chronic renal failure and treated with 100 mg of doravirine…”
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Severe Plasmodium malariae Malaria in a Patient With Multiple Susceptibility Genes
Published in Journal of travel medicine (01-05-2010)“…We present a case of severe malaria due to Plasmodium malariae. Genetic testing showed that the patient was homozygous for five important gene polymorphisms…”
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Efficacy and safety of anakinra in adults presenting deteriorating respiratory symptoms from COVID-19: A randomized controlled trial
Published in PloS one (04-08-2022)“…Objective We aimed to investigate whether anakinra, an interleukin-1receptor inhibitor, could improve outcome in moderate COVID-19 patients. Methods In this…”
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Impact of vaccination on the presence and severity of symptoms in hospitalized patients with an infection of the Omicron variant (B.1.1.529) of the SARS-CoV-2 (subvariant BA.1)
Published in Clinical microbiology and infection (01-05-2023)“…The emergence of SARS-CoV-2 variants raised questions about the extent to which vaccines designed in 2020 have remained effective. We aimed to assess whether…”
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Infected erythrocytes and plasma proteomics reveal a specific protein signature of severe malaria
Published in EMBO molecular medicine (15-02-2024)“…Cerebral malaria (CM), the most lethal complication of Plasmodium falciparum severe malaria (SM), remains fatal for 15–25% of affected children despite the…”
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Comparison of Sulfadoxine‐Pyrimethamine, Unsupervised Artemether‐Lumefantrine, and Unsupervised Artesunate‐Amodiaquine Fixed‐Dose Formulation for Uncomplicated Plasmodium falciparum Malaria in Benin: A Randomized Effectiveness Noninferiority Trial
Published in The Journal of infectious diseases (01-07-2009)“…Background. We compared sulfadoxine‐pyrimethamine (SP) with unsupervised artemether‐lumefantrine (AL) and unsupervised amodiaquine‐artesunate (ASAQ) fixed‐dose…”
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Cancer and Infective Endocarditis: Characteristics and Prognostic Impact
Published in Frontiers in cardiovascular medicine (11-11-2021)“…Background: The interplay between cancer and IE has become of increasing interest. This study sought to assess the prevalence, baseline characteristics,…”
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Toward an optimization of empirical antibiotic therapy in acute graft pyelonephritis: A retrospective multicenter study
Published in Infectious diseases now (Online) (01-08-2024)“…•A high rate of resistance among Enterobacterales responsible for acute graft pyelonephritis (AGPN) in western France (and probably the entire country).•None…”
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