Search Results - "Fattal, Michele"
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Differential effects of cyclosporin A and tacrolimus on magnesium influx in Caco2 cells
Published in Journal of pharmacy & pharmaceutical sciences (01-01-2012)“…Hypomagnesemia with urinary magnesium (Mg) wasting is a well acknowledged side effect of cyclosporin A (CsA) and tacrolimus (FK506) treatments. TRPM6, TRPM7…”
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Experimental tracheal and tracheoesophageal allotransplantation
Published in The Journal of thoracic and cardiovascular surgery (01-10-1995)“…We investigated the effects of allograft perfusion with a preservative technique and of combined thyrotracheoesophageal implantation on airway epithelium of…”
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3
Efavirenz does not interact with the ABCB1 transporter at the blood-brain barrier
Published in Pharmaceutical research (01-07-2006)“…This work characterizes the interactions between efavirenz (EFV) and P-glycoprotein (P-gp/ABCB1) at the blood-brain barrier (BBB) and predicts the possible…”
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Impact of Cyclosporine A on Magnesium Homeostasis : Clinical Observation in Lung Transplant Recipients and Experimental Study in Mice
Published in Transplantation (15-08-2008)“…Hypomagnesemia is a common finding in patients receiving cyclosporine A (CsA) therapy. The relationship between CsA-induced hypomagnesemia and nephrotoxicity…”
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5
Magnesium-deficiency does not alter calcineurin inhibitors activity in mice
Published in Transplant immunology (01-01-2012)“…Abstract Introduction Tacrolimus (TAC) and cyclosporin (CsA) are commonly responsible for hypomagnesemia that predisposes in turn for hypertension, renal…”
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Threshold to N-methyl-D-aspartate-induced seizures in mice undergoing chronic nutritional magnesium deprivation is lowered in a way partly responsive to acute magnesium and antioxidant administrations
Published in British journal of nutrition (01-02-2009)“…Magnesium deficiency may be induced by a diet impoverished in magnesium. This nutritional deficit promotes chronic inflammatory and oxidative stresses,…”
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Neuroprotective gene profile in the brain of magnesium-deficient mice
Published in Biomedicine & pharmacotherapy (01-04-2008)“…Abstract Back ground Magnesium (Mg) deficiency may lead to serious metabolic, biological and organic dysfunctions, and cause various clinical disorders. In the…”
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Effect of hypomagnesemia on allogeneic activation in mice
Published in Transplant immunology (01-11-2008)“…Abstract Introduction Magnesium (Mg) plays an essential role in a wide range of fundamental cellular reactions. It has been reported that in rodents…”
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Biodistribution and anticancer activity of a new vinca alkaloid encapsulated into long-circulating liposomes
Published in Journal of liposome research (01-03-2010)“…S12363 is a potent therapeutic agent with a strong in vitro activity against a variety of tumor types but also a high in vivo toxicity. Loading of this drug…”
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A study of magnesium deficiency in human and experimental pulmonary hypertension
Published in Magnesium research (01-03-2012)“…Pulmonary hypertension (PH) is defined as an increase in mean pulmonary arterial pressure above 25 mmHg. Pulmonary vasoconstriction, cellular proliferation,…”
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11
Engineering a GABA endowed with pharmacological CNS activity when given by an extracerebral route
Published in Medicinal chemistry research (01-05-2009)“…Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter physiologically active in the central nervous system (CNS), being synthesised and…”
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12
Allogeneic activation is attenuated in a model of mouse lung perfused with magnesium-deficient blood
Published in Transplant immunology (01-11-2006)“…Hypomagnesemia, which is frequently observed in patients treated with calcineurin inhibitors to prevent rejection after allogeneic transplantation, has been…”
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13
MDR1A (ABCB1)-Deficient CF-1 Mutant Mice are Susceptible to Cerebral Malaria Induced by Plasmodium Berghei ANKA
Published in The Journal of parasitology (01-10-2008)“…Under experimental conditions, Plasmodium berghei infection causes cerebral malaria (CM) in susceptible strains of mice such as C57BL/6 and CBA/Ca, whereas…”
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14
Heterotopic en bloc tracheobronchial transplantation with direct revascularization in pigs
Published in The Journal of thoracic and cardiovascular surgery (01-06-2004)“…This article describes the application of a novel aortic tube technique for directly revascularized tracheobronchial transplantation with dual blood supply in…”
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E-selectin early overexpression induced by allogeneic activation in isolated mouse lung
Published in Transplantation (15-11-2004)“…The interaction between host lymphocytes and graft endothelial cells plays an important role in graft rejection. Using our model of isolated ventilated lung…”
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Role of E-selectin in cell apoptosis induced by allogeneic blood perfusion in isolated mouse lung
Published in Transplantation (15-09-2005)“…In a model of mouse isolated lung, we have recently demonstrated that E-selectin is involved in the activation of endothelial cells induced by allogeneic blood…”
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Endotiwlial cell early activation induced by allogeneic lymphocytes in isolated perfused mouse lung
Published in Transplantation (2002)Get full text
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Endothelial cell early activation induced by allogeneic lymphocytes in isolated perfused mouse lung
Published in Transplantation (27-11-2002)“…The early inflammatory response induced following vascularized organ allotransplantation is mediated by adhesin-ligand interactions between blood leukocytes…”
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Influence of the pro-inflammatory cytokines on P-glycoprotein expression and functionality
Published in Journal of pharmacy & pharmaceutical sciences (17-11-2004)“…P-glycoprotein (P-gp) is involved in the transport of many drugs at different barriers with consequence in terms of drug distribution and elimination. The…”
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Heterotopic pig model for direct revascularization and venous drainage of tracheal allografts
Published in The Journal of thoracic and cardiovascular surgery (01-12-1994)Get full text
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