Search Results - "Fattal, Michele"

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    Differential effects of cyclosporin A and tacrolimus on magnesium influx in Caco2 cells by Gouadon, Elodie, Lecerf, Florence, German-Fattal, Michèle

    “…Hypomagnesemia with urinary magnesium (Mg) wasting is a well acknowledged side effect of cyclosporin A (CsA) and tacrolimus (FK506) treatments. TRPM6, TRPM7…”
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    Journal Article
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    Experimental tracheal and tracheoesophageal allotransplantation by Macchiarini, Paolo, Mazmanian, Guy-Michel, de Montpréville, Vincent, Dulmet, Elisabeth, Fattal, Michèle, Lenot, Bernard, Chapelier, Alain, Dartevelle, Philippe

    “…We investigated the effects of allograft perfusion with a preservative technique and of combined thyrotracheoesophageal implantation on airway epithelium of…”
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    Efavirenz does not interact with the ABCB1 transporter at the blood-brain barrier by DIRSON, Grégoire, FERNANDEZ, Christine, HINDLET, Patrick, ROUX, Francoise, GERMAN-FATTAL, Michèle, GIMENEZ, Francois, FARINOTTI, Robert

    Published in Pharmaceutical research (01-07-2006)
    “…This work characterizes the interactions between efavirenz (EFV) and P-glycoprotein (P-gp/ABCB1) at the blood-brain barrier (BBB) and predicts the possible…”
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    Impact of Cyclosporine A on Magnesium Homeostasis : Clinical Observation in Lung Transplant Recipients and Experimental Study in Mice by SABBAGH, Fadi, EL TAWIL, Zeina, LECERF, Florence, HULIN, Anne, MAUROIS, Pierre, DARTEVELLE, Philippe, BAC, Pierre, GERMAN-FATTAL, Michèle

    Published in Transplantation (15-08-2008)
    “…Hypomagnesemia is a common finding in patients receiving cyclosporine A (CsA) therapy. The relationship between CsA-induced hypomagnesemia and nephrotoxicity…”
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    Magnesium-deficiency does not alter calcineurin inhibitors activity in mice by Hulin, Anne, Lamrani, Lilia, Sabbagh, Fadi, Tallet, Anne, Lecerf, Florence, Bac, Pierre, German-Fattal, Michèle

    Published in Transplant immunology (01-01-2012)
    “…Abstract Introduction Tacrolimus (TAC) and cyclosporin (CsA) are commonly responsible for hypomagnesemia that predisposes in turn for hypertension, renal…”
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    Neuroprotective gene profile in the brain of magnesium-deficient mice by German-Fattal, Michèle, Lecerf, Florence, Sabbagh, Fadi, Maurois, Pierre, Durlach, Jean, Bac, Pierre

    Published in Biomedicine & pharmacotherapy (01-04-2008)
    “…Abstract Back ground Magnesium (Mg) deficiency may lead to serious metabolic, biological and organic dysfunctions, and cause various clinical disorders. In the…”
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    Effect of hypomagnesemia on allogeneic activation in mice by Sabbagh, Fadi, Lecerf, Florence, Hulin, Anne, Bac, Pierre, German-Fattal, Michèle

    Published in Transplant immunology (01-11-2008)
    “…Abstract Introduction Magnesium (Mg) plays an essential role in a wide range of fundamental cellular reactions. It has been reported that in rodents…”
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    Biodistribution and anticancer activity of a new vinca alkaloid encapsulated into long-circulating liposomes by Chemin, Caroline, Péan, Jean-Manuel, Pape, Alain Le, Delbos, Jean-Marie, German-Fattal, Michèle, Wüthrich, Patrick, Couvreur, Patrick

    Published in Journal of liposome research (01-03-2010)
    “…S12363 is a potent therapeutic agent with a strong in vitro activity against a variety of tumor types but also a high in vivo toxicity. Loading of this drug…”
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    A study of magnesium deficiency in human and experimental pulmonary hypertension by Chaumais, Marie-Camille, Lecerf, Florence, Fattal, Soly, Savale, Laurent, Günther, Sven, Huertas, Alice, Montani, David, Perros, Frederic, Humbert, Marc, German-Fattal, Michèle

    Published in Magnesium research (01-03-2012)
    “…Pulmonary hypertension (PH) is defined as an increase in mean pulmonary arterial pressure above 25 mmHg. Pulmonary vasoconstriction, cellular proliferation,…”
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    Allogeneic activation is attenuated in a model of mouse lung perfused with magnesium-deficient blood by Sabbagh, Fadi, Lecerf, Florence, Maurois, Pierre, Bac, Pierre, German-Fattal, Michèle

    Published in Transplant immunology (01-11-2006)
    “…Hypomagnesemia, which is frequently observed in patients treated with calcineurin inhibitors to prevent rejection after allogeneic transplantation, has been…”
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    MDR1A (ABCB1)-Deficient CF-1 Mutant Mice are Susceptible to Cerebral Malaria Induced by Plasmodium Berghei ANKA by de Lagerie, Sylvie Barraud, Fernandez, Christine, German-Fattal, Michèle, Gantier, Jean-Charles, Gimenez, François, Farinotti, Robert

    Published in The Journal of parasitology (01-10-2008)
    “…Under experimental conditions, Plasmodium berghei infection causes cerebral malaria (CM) in susceptible strains of mice such as C57BL/6 and CBA/Ca, whereas…”
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    Heterotopic en bloc tracheobronchial transplantation with direct revascularization in pigs by Macedo, Amarilio, Fadel, Elie, Mazmanian, Guy-Michel, de Montpréville, Vincent, German-Fattal, Michèle, Mussot, Sacha, Chapelier, Alain, Dartevelle, Philippe G

    “…This article describes the application of a novel aortic tube technique for directly revascularized tracheobronchial transplantation with dual blood supply in…”
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    E-selectin early overexpression induced by allogeneic activation in isolated mouse lung by JOUCHER, Franck, MAZMANIAN, Guy-Michel, GERMAN-FATTAL, Michele

    Published in Transplantation (15-11-2004)
    “…The interaction between host lymphocytes and graft endothelial cells plays an important role in graft rejection. Using our model of isolated ventilated lung…”
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    Role of E-selectin in cell apoptosis induced by allogeneic blood perfusion in isolated mouse lung by JOUCHER, Franck, MAZMANIAN, Guy-Michel, GERMAN-FATTAL, Michele

    Published in Transplantation (15-09-2005)
    “…In a model of mouse isolated lung, we have recently demonstrated that E-selectin is involved in the activation of endothelial cells induced by allogeneic blood…”
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    Endothelial cell early activation induced by allogeneic lymphocytes in isolated perfused mouse lung by Joucher, Franck, Mazmanian, Guy-Michel, German-Fattal, Michele

    Published in Transplantation (27-11-2002)
    “…The early inflammatory response induced following vascularized organ allotransplantation is mediated by adhesin-ligand interactions between blood leukocytes…”
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    Influence of the pro-inflammatory cytokines on P-glycoprotein expression and functionality by Fernandez, Christine, Buyse, Marion, German-Fattal, Michèle, Gimenez, François

    “…P-glycoprotein (P-gp) is involved in the transport of many drugs at different barriers with consequence in terms of drug distribution and elimination. The…”
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