Search Results - "Fatima, Sulail"
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A glance at the therapeutic potential of irisin against diseases involving inflammation, oxidative stress, and apoptosis: An introductory review
Published in Pharmacological research (01-03-2018)“…[Display omitted] Irisin is a hormone-like molecule mainly released by skeletal muscles in response to exercise. Irisin induces browning of the white adipose…”
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Oxidative stress induces mitochondrial iron overload and ferroptotic cell death
Published in Scientific reports (19-09-2023)“…Oxidative stress has been shown to induce cell death in a wide range of human diseases including cardiac ischemia/reperfusion injury, drug induced…”
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Role of ferroptosis in the pathogenesis of heart disease
Published in Frontiers in physiology (10-09-2024)“…Ferroptosis is a new form of regulated necrosis characterized by iron-dependent lipid peroxidation, leading to irreparable lipid damage, membrane…”
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Protective effects of various dosage of Curcumin against morphine induced apoptosis and oxidative stress in rat isolated hippocampus
Published in Pharmacological reports (01-04-2015)“…During recent years, the defensive role of Curcumin against oxidative stress and apoptosis has been experimentally documented. Long term consumption of…”
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Pharmacological evidence for lithium-induced neuroprotection against methamphetamine-induced neurodegeneration via Akt-1/GSK3 and CREB-BDNF signaling pathways
Published in Iranian journal of basic medical sciences (01-08-2019)“…Neurodegeneration is an outcome of Methamphetamine (METH) abuse. Studies have emphasized on the neuroprotective properties of lithium. The current study is…”
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Synergistic Effects of Social Isolation and Morphine Addiction on Reduced Neurogenesis and BDNF Levels and the Resultant Deficits in Cognition and Emotional State in Male Rats
Published in Current molecular pharmacology (01-11-2016)“…Addiction to drugs of abuse is a devastating condition which results in deterioration of brain function. On the other hand, social isolation also produces…”
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Ameliorative effects of hydrogen sulfide (NaHS) on chronic kidney disease-induced brain dysfunction in rats: implication on role of nitric oxide (NO) signaling
Published in Metabolic brain disease (01-12-2018)“…Chronic kidney disease (CKD) is a major public health problem worldwide and is associated with spatial learning deficits. The aim of the present study was to…”
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The role of nitric oxide on the antiarrhythmic effects of ketamine/xylazine in a rat model of acute cardiac ischemia-reperfusion
Published in Current research in physiology (01-01-2022)“…The prevalence of ventricular arrhythmias during general anesthesia is about 70%. In experimental studies on the antiarrhythmic effects of different agents,…”
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Acute sleep deprivation preconditions the heart against ischemia/ reperfusion injury: the role of central GABA-A receptors
Published in Iranian journal of basic medical sciences (01-11-2017)“…Central γ-aminobutyric acid (GABA) neurotransmission modulates cardiovascular functions and sleep. Acute sleep deprivation (ASD) affects functions of various…”
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Effect of Lactation on myocardial vulnerability to ischemic insult in rats
Published in Arquivos brasileiros de cardiologia (01-05-2017)“…Cardiovascular diseases are the leading cause of mortality and long-term disability worldwide. Various studies have suggested a protective effect of lactation…”
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Social isolation is associated with reduced neurogenesis, impaired spatial working memory performance, and altered anxiety levels in male rats
Published in Open access animal physiology (01-01-2015)“…Background: Social isolation has some adverse behavioral effects. It has been shown that neurogenesis is essential for improvement of behavioral function. The…”
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Study of the effects of controlled morphine administration for treatment of anxiety, depression and cognition impairment in morphine-addicted rats
Published in Advanced biomedical research (2016)“…Morphine dependency usually results in undesired outcomes such as anxiety, depression, and cognitive alterations. In this study, morphine was used to manage…”
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The Neuroprotective Effect of Curcumin Against Nicotine-Induced Neurotoxicity is Mediated by CREB–BDNF Signaling Pathway
Published in Neurochemical research (01-10-2017)“…Nicotine abuse adversely affects brain and causes apoptotic neurodegeneration. Curcumin- a bright yellow chemical compound found in turmeric is associated with…”
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Curcumin confers neuroprotection against alcohol-induced hippocampal neurodegeneration via CREB-BDNF pathway in rats
Published in Biomedicine & pharmacotherapy (01-03-2017)“…Abstract Background Alcohol abuse causes severe damage to the brain neurons. Studies have reported the neuroprotective effects of curcumin against…”
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Post-infarct morphine treatment reduces apoptosis and myofibroblast density in a rat model of cardiac ischemia-reperfusion
Published in European journal of pharmacology (15-11-2020)“…Following myocardial ischemia, the cardiac tissue undergoes both, physiological and pathological changes to compensate the initial loss of function. Long-term…”
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Topiramate via NMDA, AMPA/kainate, GABA A and Alpha2 receptors and by modulation of CREB/BDNF and Akt/GSK3 signaling pathway exerts neuroprotective effects against methylphenidate-induced neurotoxicity in rats
Published in Journal of neural transmission (Vienna, Austria : 1996) (01-11-2017)“…Chronic abuse of methylphenidate (MPH) often causes neuronal cell death. Topiramate (TPM) carries neuroprotective effects, but its exact mechanism of action…”
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Effects of acute doses of methylphenidate on inflammation and oxidative stress in isolated hippocampus and cerebral cortex of adult rats
Published in Journal of Neural Transmission (2017)“…Methylphenidate (MPH) is a stimulatory agent in brain with unknown long-term consequences. In this study, MPH-induced neurodegeneration in adult rat brain was…”
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Topiramate via NMDA, AMPA/kainate, GABAA and Alpha2 receptors and by modulation of CREB/BDNF and Akt/GSK3 signaling pathway exerts neuroprotective effects against methylphenidate-induced neurotoxicity in rats
Published in Journal of Neural Transmission (01-11-2017)“…Chronic abuse of methylphenidate (MPH) often causes neuronal cell death. Topiramate (TPM) carries neuroprotective effects, but its exact mechanism of action…”
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Melatonin Protects Against Titanium Oxide-Induced Neurotoxicity: Neurochemical, Neurobehavioral, and Histopathological Evidences
Published in Biological trace element research (01-08-2023)“…titania (titanium dioxide, TiO 2 ) is known to induce neurotoxicity and CNS dysfunctions. Numerous studies have explored the neuroprotective effects of…”
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