Search Results - "Fatemeh Azadegan"
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Design of a multi-epitope vaccine against cervical cancer using immunoinformatics approaches
Published in Scientific reports (11-06-2021)“…Cervical cancer, caused by human papillomavirus (HPV), is the fourth most common type of cancer among women worldwide. While HPV prophylactic vaccines are…”
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GJB2‐related hearing loss in central Iran: Review of the spectrum and frequency of gene mutations
Published in Annals of human genetics (01-03-2020)“…Mutations in the GJB2 gene are a main cause of autosomal‐recessive nonsyndromic hearing loss (ARNSHL) in many populations. Previous studies have estimated the…”
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Update of spectrum c.35delG and c.‐23+1G>A mutations on the GJB2 gene in individuals with autosomal recessive nonsyndromic hearing loss
Published in Annals of human genetics (01-01-2019)“…Hearing loss (HL) is the most common birth defect and the most prevalent sensorineural condition worldwide. It is associated with more than 1,000 mutations in…”
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Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach
Published in Scientific reports (11-05-2022)“…Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV outbreaks have been documented, the majority of which have occurred…”
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In silico design of a multi-epitope vaccine against HPV16/18
Published in BMC bioinformatics (02-08-2022)“…Cervical cancer is the fourth most common cancer affecting women and is caused by human Papillomavirus (HPV) infections that are sexually transmitted. There…”
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The biological functions of IL-17 in different clinical expressions of Helicobacter pylori-infection
Published in Microbial pathogenesis (01-04-2015)“…Helicobacter pylori (H. pylori) infection is regarded as the major cause of various gastric diseases (gastritis, peptic ulcers and gastric cancer) and induces…”
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Association between virulence factors of helicobacter pylori and gastric mucosal interleukin-18 mRNA expression in dyspeptic patients
Published in Microbial pathogenesis (01-12-2013)“…Helicobacter pylori (Hp) infection is associated with gastritis and marked infiltration of the gastric mucosa by several cytokines secreting inflammatory cells…”
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Genetics of hereditary hearing loss in east Iran population: A systematic review of GJB2 mutations
Published in Intractable & Rare Diseases Research (31-08-2019)“…Mutations in the GJB2 gene are the most common cause of pre-lingual hearing loss (HL) worldwide. Previous studies have shown the frequency of GJB2 mutations to…”
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Comparative Immune Response in Children and Adults with H. pylori Infection
Published in Journal of immunology research (01-01-2015)“…Helicobacter pylori (H. pylori) infection is generally acquired during early childhood; therefore, the immune response which usually takes place at this age…”
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Virulence factors of Helicobacter pylori vacA increase markedly gastric mucosal TGF-β1 mRNA expression in gastritis patients
Published in Microbial pathogenesis (01-02-2014)“…Helicobacter pylori (H. pylori) infection is the main cause of gastric inflammation. Regulatory T cells (Treg cells) suppress the activation and proliferation…”
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Relationship between mucosal TNF-α expression and Th1, Th17, Th22 and Treg responses in Helicobacter pylori infection
Published in AMB Express (03-09-2022)“…Helicobacter pylori ( H. pylori )-induced gastric inflammation in the gastric mucosa and significantly increases the risk of developing gastritis and peptic…”
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Genetics of Hearing Loss in North Iran Population: An Update of Spectrum and Frequency of GJB2 Mutations
Published in Journal of audiology & otology (01-10-2019)“…Diagnosis of pre-lingual hearing loss (HL) is difficult owing to the high number of genes responsible. The most frequent cause of HL is DFNB1 due to mutations…”
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A Study of Autoantibodies Against some Central Nervous System Antigens and the IL-35 Serum Level in Schizophrenia
Published in Iranian journal of allergy, asthma, and immunology (01-08-2022)“…Schizophrenia (SCZ) is a debilitating mental disorder with various causes involving complex interactions between genetic factors and environmental agents. The…”
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Mutations in GJB2 as Major Causes of Autosomal Recessive Non-Syndromic Hearing Loss: First Report of c.299-300delAT Mutation in Kurdish Population of Iran
Published in Journal of audiology & otology (01-01-2019)“…Autosomal recessive non-syndromic hearing loss (ARNSHL) with genetic origin is common (1/2000 births). ARNSHL can be associated with mutations in gap junction…”
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The role of Th1 and Th17 cells in glomerulonephritis
Published in Journal of nephropathology (01-04-2015)“…Context: T helper (Th) cells as an important part of the immune is responsible for elimination of invading pathogens. But, if Th cell responses are not…”
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The role and spectrum of SLC26A4 mutations in Iranian patients with autosomal recessive hereditary deafness
Published in International journal of audiology (01-02-2015)“…Abstract Objective: To determine the prevalence and types of SLC26A4 mutations and the relevant phenotypes in a series of Iranian deaf patients. Design: A…”
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Frequency of virulence-associated genotypes of Helicobacter pylori and their correlation with clinical outcome and histological parameters in infected patients
Published in Heliyon (01-07-2021)“…Helicobacter pylori (H. pylori) is a gram-negative which can cause several gastroduodenal diseases, including gastritis and peptic ulcer disease (PUD)…”
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Screening of 10 DFNB Loci Causing Autosomal Recessive Non-Syndromic Hearing Loss in Two Iranian Populations Negative for GJB2 Mutations
Published in Iranian journal of public health (01-09-2019)“…Autosomal recessive non-syndromic hearing loss (ARNSHL), one of the global public health concerns, is marked by a high degree of genetic heterogeneity. The…”
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Association of the virulence factors of Helicobacter pylori and gastric mucosal interleukin-17/23 mRNA expression in dyspeptic patients
Published in EXCLI journal (01-01-2013)“…The molecular pathways that control Helicobacter pylori (Hp)-associated inflammatory reaction are complex, but locally induced cytokines and virulence factors…”
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Correlation of miR-24-3p and miR-595 expression with CCL3, CCL4, IL1-β, TNFαIP3, and NF-κBIα genes in PBMCs of patients with coronary artery disease
Published in EXCLI journal (01-09-2022)“…Inflammation has been well recognized to play an important role in developing coronary artery disease (CAD). By regulating essential genes in this pathway…”
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