Adherence to the Mediterranean Diet in Preventing Major Cardiovascular Events in Patients with Ischemic Heart Disease: The EVA Study

Adherence to healthy dietary patterns, such as the Mediterranean diet (Med-diet), is recommended for the maintenance of cardiovascular health. The determinants for adherence to Med-diet and its importance in secondary cardiovascular disease prevention are still unclear. The aim of the study was to e...

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Published in:Nutrients Vol. 15; no. 14; p. 3150
Main Authors: Cangemi, Roberto, Miglionico, Marzia, D'Amico, Tania, Fasano, Salvatore, Proietti, Marco, Romiti, Giulio Francesco, Corica, Bernadette, Stefanini, Lucia, Tanzilli, Gaetano, Basili, Stefania, Raparelli, Valeria, Tarsitano, Maria Grazia, Eva Collaborative Group
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 01-07-2023
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Summary:Adherence to healthy dietary patterns, such as the Mediterranean diet (Med-diet), is recommended for the maintenance of cardiovascular health. The determinants for adherence to Med-diet and its importance in secondary cardiovascular disease prevention are still unclear. The aim of the study was to evaluate the influence of sex- and psycho-socio-cultural (i.e., gender-related) factors on Med-diet adherence and its role in preventing major cardiovascular events (MACEs) in patients with ischemic heart disease (IHD). Med-diet adherence was evaluated among 503 consecutive adults with IHD. MACEs were collected during a long-term follow-up. Male Bem Sex-Role Inventory score (i.e., male personality traits) and physical functional capacity were associated with higher adherence, while cohabitation with a smoker and physical inactivity with poorer adherence. During a median follow-up of 22 months, 48 participants experienced MACEs (17.5%, 8.1%, and 3.9% of patients with low, medium, and high adherence, respectively; = 0.016). At multivariate Cox--regression analysis, a greater adherence remained inversely associated with MACEs (HR: 0.49; 95% CI: 0.29-0.82; = 0.006) after adjusting for confounding factors. The study suggests that gender-related factors have a role in maintaining a healthy dietary pattern. Improving Med-diet adherence may lower the risk of recurring cardiovascular events.
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Full names of EVA Collaborative Group are listed in the Acknowledgements section.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu15143150