Search Results - "Fasana, Elisa"

Targeting pathways of C-tail-anchored proteins by Borgese, Nica, Fasana, Elisa

“…A large group of diverse, functionally important, and differently localized transmembrane proteins, share a particular membrane topology, consisting of a…”
Get full text

N‐glycan processing selects ERAD‐resistant misfolded proteins for ER‐to‐lysosome‐associated degradation by Fregno, Ilaria, Fasana, Elisa, Soldà, Tatiana, Galli, Carmela, Molinari, Maurizio

“…Efficient degradation of by‐products of protein biogenesis maintains cellular fitness. Strikingly, the major biosynthetic compartment in eukaryotic cells, the…”
Get full text

Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D’Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

“…The endoplasmic reticulum (ER) is a site of protein biogenesis in eukaryotic cells. Perturbing ER homeostasis activates stress programs collectively called the…”
Get full text

Specificity and Regulation of the Endoplasmic Reticulum‐Associated Degradation Machinery by Merulla, Jessica, Fasana, Elisa, Soldà, Tatiana, Molinari, Maurizio

“…The endoplasmic reticulum‐associated degradation (ERAD) machinery selects native and misfolded polypeptides for dislocation across the ER membrane and…”
Get full text

VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum by Fasana, Elisa, Fossati, Matteo, Ruggiano, Annamaria, Brambillasca, Silvia, Hoogenraad, Casper C, Navone, Francesca, Francolini, Maura, Borgese, Nica

“…VAPB (vesicle-associated membrane protein-associated protein B) is an endoplasmic reticulum (ER)-resident tail-anchored adaptor protein involved in lipid…”
Get full text

Endoplasmic Reticulum and Lysosomal Quality Control of Four Nonsense Mutants of Iduronate 2-Sulfatase Linked to Hunter's Syndrome by Marazza, Alessandro, Galli, Carmela, Fasana, Elisa, Sgrignani, Jacopo, Burda, Patricie, Fassi, Enrico M A, Baumgartner, Matthias, Cavalli, Andrea, Molinari, Maurizio

“…Hunter's syndrome (mucopolysaccharidosis type II) is a rare X-linked lysosomal storage disorder caused by mutations in the iduronate-2-sulfatase (IDS) gene…”
Get more information

Mechanisms of insertion of tail-anchored proteins into the membrane of the endoplasmic reticulum by Colombo, Sara F, Fasana, Elisa

“…Tail-anchored proteins (TAPs) are a subclass of type II integral membrane proteins that carry out important and diverse functions within cells. Structurally,…”
Get more information

Erratum: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D'Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

Get full text

ER‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport by Fregno, Ilaria, Fasana, Elisa, Bergmann, Timothy J, Raimondi, Andrea, Loi, Marisa, Soldà, Tatiana, Galli, Carmela, D'Antuono, Rocco, Morone, Diego, Danieli, Alberto, Paganetti, Paolo, van Anken, Eelco, Molinari, Maurizio

“…Maintenance of cellular proteostasis relies on efficient clearance of defective gene products. For misfolded secretory proteins, this involves dislocation from…”
Get full text

ER-to-lysosome-associated degradation acts as failsafe mechanism upon ERAD dysfunction by Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Soldà, Tatiana, Molinari, Maurizio

“…The endoplasmic reticulum (ER) produces proteins destined to organelles of the endocytic and secretory pathways, the plasma membrane, and the extracellular…”
Get full text

A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex by Forrester, Alison, De Leonibus, Chiara, Grumati, Paolo, Fasana, Elisa, Piemontese, Marilina, Staiano, Leopoldo, Fregno, Ilaria, Raimondi, Andrea, Marazza, Alessandro, Bruno, Gemma, Iavazzo, Maria, Intartaglia, Daniela, Seczynska, Marta, van Anken, Eelco, Conte, Ivan, De Matteis, Maria Antonietta, Dikic, Ivan, Molinari, Maurizio, Settembre, Carmine

“…Autophagy is a cytosolic quality control process that recognizes substrates through receptor‐mediated mechanisms. Procollagens, the most abundant gene products…”
Get full text

Uncovering Common Principles in Protein Export of Malaria Parasites by Grüring, Christof, Heiber, Arlett, Kruse, Florian, Flemming, Sven, Franci, Gianluigi, Colombo, Sara F., Fasana, Elisa, Schoeler, Hanno, Borgese, Nica, Stunnenberg, Hendrik G., Przyborski, Jude M., Gilberger, Tim-Wolf, Spielmann, Tobias

“…For proliferation, the malaria parasite Plasmodium falciparum needs to modify the infected host cell extensively. To achieve this, the parasite exports…”
Get full text

A selective ER ‐phagy exerts procollagen quality control via a Calnexin‐ FAM 134B complex by Forrester, Alison, De Leonibus, Chiara, Grumati, Paolo, Fasana, Elisa, Piemontese, Marilina, Staiano, Leopoldo, Fregno, Ilaria, Raimondi, Andrea, Marazza, Alessandro, Bruno, Gemma, Iavazzo, Maria, Intartaglia, Daniela, Seczynska, Marta, van Anken, Eelco, Conte, Ivan, De Matteis, Maria Antonietta, Dikic, Ivan, Molinari, Maurizio, Settembre, Carmine

Get full text

Correction: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D'Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

“…Nature Cell Biology 18, 1173–1184 (2016); published online 17 October 2016; corrected after print 18 November 2016. In the version of this Article originally…”
Get full text

Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J, Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D'Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

Get full text