Search Results - "Farson, Deborah"

Development and characterization of a cell line for large-scale, serum-free production of recombinant adeno-associated viral vectors by Farson, Deborah, Harding, Thomas C., Tao, Lucy, Liu, Jun, Powell, Sandra, Vimal, Vishalini, Yendluri, Satyasri, Koprivnikar, Kathryn, Ho, Kenneth, Twitty, Christopher, Husak, Paul, Lin, Andy, Snyder, Richard O., Donahue, Brian A.

“…Background One of the major limitations to the use of adeno‐associated virus (AAV) vectors for gene therapy has been the difficulty in producing enough vector…”
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A new-generation stable inducible packaging cell line for lentiviral vectors by Farson, D, Witt, R, McGuinness, R, Dull, T, Kelly, M, Song, J, Radeke, R, Bukovsky, A, Consiglio, A, Naldini, L

“…We have successfully generated and characterized a stable packaging cell line for HIV-1-based vectors. To allow safe production of vector, a minimal packaging…”
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kat: A High-Efficiency Retroviral Transduction System for Primary Human T Lymphocytes by Finer, Mitchell H., Dull, Thomas J., Qin, Lu, Farson, Deborah, Roberts, Margo R.

“…We describe a novel retroviral packaging system in which high titer amphotropic retrovirus was produced without the need to generate stable producer clones,…”
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Development of Novel E1-Complementary Cells for Adenoviral Production Free of Replication-Competent Adenovirus by Farson, Deborah, Tao, Lucy, Ko, Derek, Li, Qun, Brignetti, Dominic, Segawa, Karrie, Mittelstaedt, Denice, Harding, Thomas, Yu, De-chao, Li, Yuanhao

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775. An Novel Adenoviral E1 Complementary Cell for Eliminating Replication Competent Adenovirus (RCA) during Viral Production by Farson, Deborah, Tao, Lucy, Ko, Derek, Harding, Thomas, Yu, De-chao, Li, Yuanhao

“…Production of recombinant adenoviruses from 293 cells and other recently developed adenoviral E1-complementary cell lines have the potential to produce low…”
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82. Adaptation of a lentiviral vector producer cell line to reduced-serum, suspension culture for large scale production by Townsend, Kay, Chen, Yong, Dayao, Jonathan, Farson, Deborah, Miller, William M, Lin, Andy

“…The current process for producing lentiviral vector by transient transfection in 10-layer cell factories is costly, labor-intensive, and ineffective for…”
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Antigen-Specific Cytolysis by Neutrophils and NK Cells Expressing Chimeric Immune Receptors Bearing {zeta} or {gamma} Signaling Domains by Roberts, Margo R, Cooke, Keegan S, Tran, Annie-Chen, Smith, Kent A, Lin, Wei Yu, Wang, Martin, Dull, Thomas J, Farson, Deborah, Zsebo, Krisztina M, Finer, Mitchell H

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Antigen-specific cytolysis by neutrophils and NK cells expressing chimeric immune receptors bearing zeta or gamma signaling domains by Roberts, M R, Cooke, K S, Tran, A C, Smith, K A, Lin, W Y, Wang, M, Dull, T J, Farson, D, Zsebo, K M, Finer, M H

“…TCR- and IgG-binding Fc receptors (Fc gamma R) mediate a variety of critical biologic activities including cytolysis via the structurally related zeta- and…”
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Development of novel E1-complementary cells for adenoviral production free of replication-competent adenovirus by Farson, Deborah, Tao, Lucy, Ko, Derek, Li, Qun, Brignetti, Dominic, Segawa, Karrie, Mittelstaedt, Denice, Harding, Thomas, Yu, De-Chao, Li, Yuanhao

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Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells by Li, M.L, Aggeler, J, Farson, D.A, Hatier, C, Hassell, J, Bissell, M.J

“…When primary mouse mammary epithelial cells are cultured on plastic, they rapidly lose their ability to synthesize and secrete most milk proteins even in the…”
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Large-scale manufacturing of safe and efficient retrovirus packaging lines for use in immunotherapy protocols by Farson, Deborah, McGuinness, Ryan, Dull, Tom, Limoli, Kay, Lazar, Richard, Jalali, Sayeh, Reddy, Sridhar, Pennathur-Das, Rukmini, Broad, David, Finer, Mitchell

“…Background The use of gene modified T lymphocytes for immunotherapy in a cancer or AIDS clinical trial requires an efficient, safe ex vivo method for…”
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Lumen Formation by Epithelial Cell Lines in Response to Collagen Overlay: A Morphogenetic Model in Culture by Hall, H. Glenn, Farson, Deborah A., Bissell, Mina J.

“…Two cell lines--Madin-Darby canine kidney (MDCK) and normal murine mammary gland (NMuMG)--growing as monolayers on collagen gels were overlaid with another…”
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Collagenous substrata regulate the nature and distribution of glycosaminoglycans produced by differentiated cultures of mouse mammary epithelial cells by Parry, G, Lee, E Y, Farson, D, Koval, M, Bissell, M J

“…We have investigated the influence of culture substrata upon glycosaminoglycans produced in primary cultures of mouse mammary epithelial cells isolated from…”
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Primary Avian Tendon Cells in Culture: An Improved System for Understanding Malignant Transformation by Schwarz, Richard I., Farson, Deborah A., Soo, Whai-Jen, Bissell, Mina J.

“…Primary avian tendon (PAT) cells which maintain their differentiated state in culture are rapidly transformed by Rous sarcoma virus. By criteria of morphology,…”
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Ascorbic acid inhibits replication and infectivity of avian RNA tumor virus [Chicken embryo fibroblasts] by Bissell, Mina J., Hatie, Carroll, Farson, Deborah A., Schwarz, Richard I., Soo, Whai-Jen

“…Ascorbic acid, at nontoxic concentrations, causes a substantial reduction in the ability of avian tumor viruses to replicate in both primary avian tendon cells…”
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Requirements for Maintaining the Embryonic State of Avian Tendon Cells in Culture by Schwarz, Richard I., Farson, Deborah A., Bissell, Mina J.

“…Primary avian tendon cells (PAT) maintain their embryonic state when cultured in medium F-12 with very low serum (0.2%) and ascorbate (50 µg per ml); that is,…”
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Cell shape and hexose transport in normal and virus-transformed cells in culture by Bissell, M J, Farson, D, Tung, A S

“…The rate of hexose transport was compared in normal and virus-transformed cells on a monolayer and in suspension. It was shown that: 1) Both trypsin-removed…”
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