Search Results - "Farrugia, Mark K"
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Association of neutrophil-lymphocyte ratio with survival in peripheral early-stage non-small cell lung cancer after stereotactic body radiation therapy
Published in BMC cancer (18-03-2023)“…The role of neutrophil-lymphocyte ratio (NLR) as a predictor for survival in single fraction SBRT-treated non-small cell lung cancer (NSCLC) patients remains…”
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KAP1 promotes proliferation and metastatic progression of breast cancer cells
Published in Cancer research (Chicago, Ill.) (15-01-2015)“…KAP1 (TRIM28) is a transcriptional regulator in embryonic development that controls stem cell self-renewal, chromatin organization, and the DNA damage…”
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Association of pre-treatment lymphocyte-monocyte ratio with survival outcome in patients with head and neck cancer treated with chemoradiation
Published in BMC cancer (21-06-2023)“…Given the role of systematic inflammation in cancer progression, lymphocyte-monocyte ratio (LMR) from peripheral blood has been suggested as a biomarker to…”
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MicroRNAs 206 and 21 Cooperate To Promote RAS-Extracellular Signal-Regulated Kinase Signaling by Suppressing the Translation of RASA1 and SPRED1
Published in Molecular and cellular biology (01-11-2014)“…Despite the low prevalence of activating point mutation of RAS or RAF genes, the RAS-extracellular signal-regulated kinase (ERK) pathway is implicated in…”
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Association of radiation dose intensity with overall survival in patients with distant metastases
Published in Cancer medicine (Malden, MA) (01-11-2021)“…Background Patients with metastatic cancer referred to radiation oncology have diverse prognoses and there is significant interest in personalizing treatment…”
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A Dose-Response Relationship to Radiotherapy for Cutaneous Lesions of Langerhans Cell Histiocytosis
Published in Case reports in oncological medicine (25-03-2021)“…Langerhans cell histiocytosis (LCH) is a rare disease, afflicting approximately 4.6 and 1-2 per 1 million children and adults, respectively. While LCH can…”
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Long-Term Survival and Failure Outcomes of Single-Fraction Stereotactic Body Radiation Therapy in Early Stage NSCLC
Published in JTO clinical and research reports (01-12-2023)“…This study aims to report our 13-year institutional experience with single-fraction stereotactic body radiation therapy (SF-SBRT) for early stage NSCLC. A…”
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Candida meningitis in an immunocompetent patient detected through (1→3)-beta-d-glucan
Published in International journal of infectious diseases (01-10-2016)“…•Candida meningitis can be a rare complication of intravenous drug abuse in an immunocompetent individual.•Testing of the cerebrospinal fluid for…”
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What to Do With Deauville 3 Interim Positron Emission Tomography/Computed Tomography Response in a Young Woman With Classic Unfavorable Hodgkin's Lymphoma: To Irradiate or Not to Irradiate?
Published in International journal of radiation oncology, biology, physics (01-01-2020)Get full text
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Kruppel-like Pluripotency Factors as Modulators of Cancer Cell Therapeutic Responses
Published in Cancer research (Chicago, Ill.) (01-04-2016)“…Tumor cells inherit from their normal precursors an extensive stress response machinery that is critical for survival in response to challenges including…”
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Re-Evaluating the Omission of Radiation Therapy in Low-Risk Patients With Early-Stage Breast Cancer
Published in Clinical breast cancer (01-10-2024)“…Traditionally, management of early-stage breast cancer has required adjuvant radiation therapy following breast conserving surgery, due to decreased local…”
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Evaluation of risk stratification using gene expression assays in patients with breast cancer receiving neoadjuvant chemotherapy
Published in Breast cancer research and treatment (01-10-2021)“…Purpose To evaluate the association of various gene expression assays with pathologic complete response (pCR) in the setting of neoadjuvant chemotherapy among…”
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Association of significant financial burden with survival for head and neck cancer patients treated with radiation therapy
Published in Oral oncology (01-04-2021)“…•HNC patients frequently struggle with financial difficulties.•Financial toxicity was associated with worse OS and CSS in HNC.•Methods to mitigate financial…”
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Systematic Review of Single-Fraction Stereotactic Body Radiation Therapy for Early Stage Non-Small-Cell Lung Cancer and Lung Oligometastases: How to Stop Worrying and Love One and Done
Published in Cancers (03-02-2022)“…Adoption of single-fraction lung stereotactic body radiation therapy (SBRT) for patients with medically inoperable early stage non-small-cell lung cancer…”
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Daily Time of Radiation Treatment Is Associated with Subsequent Oral Mucositis Severity during Radiotherapy in Head and Neck Cancer Patients
Published in Cancer epidemiology, biomarkers & prevention (01-05-2020)“…Limited treatment options are available for oral mucositis, a common, debilitating complication of cancer therapy. We examined the association between daily…”
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Concurrent β-blocker Use is Associated With Improved Outcome in Esophageal Cancer Patients Who Undergo Chemoradiation: A Retrospective Matched-pair Analysis
Published in American journal of clinical oncology (01-12-2020)“…β-blocker use has been associated with improved outcomes in a number of different malignancies; however, the impact of β-blockade in esophageal cancer is not…”
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Severe Oral Mucositis After Intensity-Modulated Radiation Therapy for Head and Neck Cancer
Published in JAMA network open (11-10-2023)“…Importance Oral mucositis (OM) is a common and debilitating adverse effect observed in patients with head and neck cancer (HNC) receiving radiation therapy…”
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Prophylactic High-Dose Gabapentin Reduces Opiate Use during Radiation Therapy for Head and Neck Squamous Cell Carcinoma
Published in Cancers (28-03-2023)“…The role of prophylactic high-dose gabapentin for the management of oral mucositis during radiation therapy for head and neck squamous cell carcinoma (HNSCC)…”
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Narrative review of the management of oral mucositis during chemoradiation for head and neck cancer
Published in Annals of translational medicine (01-05-2021)“…Oral mucositis (OM) can be a significant problem for patients undergoing radiation or chemoradiation for head and neck cancer. In modern clinical trials, grade…”
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Comparative Analysis of the Views of Oncologic Subspecialists and Palliative/Supportive Care Physicians Regarding Advanced Care Planning and End-of-Life Care
Published in American journal of hospice & palliative medicine (01-10-2018)“…Background: Early palliative/supportive care (PSC) consultation and advance care planning (ACP) improve outcomes for patients with incurable cancer. However,…”
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