Search Results - "Farris, A.B"

Banff Histopathological Consensus Criteria for Preimplantation Kidney Biopsies by Liapis, H., Gaut, J. P., Klein, C., Bagnasco, S., Kraus, E., Farris, A. B., Honsova, E., Perkowska‐Ptasinska, A., David, D., Goldberg, J., Smith, M., Mengel, M., Haas, M., Seshan, S., Pegas, K. L., Horwedel, T., Paliwa, Y., Gao, X., Landsittel, D., Randhawa, P.

“…The Banff working group on preimplantation biopsy was established to develop consensus criteria (best practice guidelines) for the interpretation of…”
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Costimulation Blockade Alters Germinal Center Responses and Prevents Antibody‐Mediated Rejection by Kim, E. J., Kwun, J., Gibby, A. C., Hong, J. J., Farris, A. B., Iwakoshi, N. N., Villinger, F., Kirk, A. D., Knechtle, S. J.

“…De novo donor‐specific antibody (DSA) after organ transplantation promotes antibody‐mediated rejection (AMR) and causes late graft loss. Previously, we…”
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Fc‐Silent Anti‐CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection by Kim, S. C., Wakwe, W., Higginbotham, L. B., Mathews, D. V., Breeden, C. P., Stephenson, A. C., Jenkins, J., Strobert, E., Price, K., Price, L., Kuhn, R., Wang, H., Yamniuk, A., Suchard, S., Farris, A. B., Pearson, T. C., Larsen, C. P., Ford, M. L., Suri, A., Nadler, S., Adams, A. B.

“…The advent of costimulation blockade provides the prospect for targeted therapy with improved graft survival in transplant patients. Perhaps the most effective…”
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Dual Islet Transplantation Modeling of the Instant Blood‐Mediated Inflammatory Reaction by Martin, B. M., Samy, K. P., Lowe, M. C., Thompson, P. W., Cano, J., Farris, A. B., Song, M., Dove, C. R., Leopardi, F. V., Strobert, E. A., Jenkins, J. B., Collins, B. H., Larsen, C. P., Kirk, A. D.

“…Islet xenotransplantation is a potential treatment for diabetes without the limitations of tissue availability. Although successful experimentally, early islet…”
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Patterns of De Novo Allo B Cells and Antibody Formation in Chronic Cardiac Allograft Rejection After Alemtuzumab Treatment by Kwun, J., Oh, B. C., Gibby, A. C., Ruhil, R., Lu, V. T., Kim, D. W., Page, E. K., Bulut, O. P., Song, M. Q., Farris, A. B., Kirk, A. D., Knechtle, S. J., Iwakoshi, N. N.

“…Even though the etiology of chronic rejection (CR) is multifactorial, donor specific antibody (DSA) is considered to have a causal effect on CR development…”
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Dr. Constantin Cope Medical Student Research Award Establishment of human metastatic colorectal cancer model in rabbit liver. Pilot study by Prieto-Ventura, V.E, Farris, A.B, Nagaraju, G.P, Bassel, E, Lawal, T.O, Kim, H.S

“…Purpose To develop a human metastatic colorectal cancer model in a rabbit liver. Materials and Methods Immunosuppression was induced in 4 adult New Zealand…”
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Expression of angiogenic factors and tumoral response after transcatheter intraarrterial treatment of rabbit VX-2 liver tumors using a novel iron-oxide nanoparticle drug delivery system by Lawal, T.O, Prieto-Ventura, V.E, Farris, A.B, Mao, H, Kim, H.S

“…Purpose To investigate tissue response and expression of angiogenic factors after targeted transcatheter intraarterial (IA) treatment of the rabbit VX-2 liver…”
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Evidence for Kidney Rejection After Combined Bone Marrow and Renal Transplantation Despite Ongoing Whole‐Blood Chimerism in Rhesus Macaques by Ramakrishnan, S. K., Page, A., Farris, A. B., Singh, K., Leopardi, F., Hamby, K., Sen, S., Polnett, A., Deane, T., Song, M., Stempora, L., Strobert, E., Kirk, A. D., Larsen, C. P., Kean, L. S.

“…Although there is evidence linking hematopoietic chimerism induction and solid organ transplant tolerance, the mechanistic requirements for chimerism‐induced…”
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Abstract No. 77: Tumorgenesis and angiogenesis factors in hepatocellular carcinoma after locoregional therapy by Farris, A.B, Dhanasekaran, R, Dursun, N, McIntosh, E, Coban, I, Adsay, V, Kim, H.S

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Banff 2013 Meeting Report: Inclusion of C4d‐Negative Antibody‐Mediated Rejection and Antibody‐Associated Arterial Lesions by Haas, M., Sis, B., Racusen, L. C., Solez, K., Glotz, D., Colvin, R. B., Castro, M. C. R., David, D. S. R., David‐Neto, E., Bagnasco, S. M., Cendales, L. C., Cornell, L. D., Demetris, A. J., Drachenberg, C. B., Farver, C. F., Farris, A. B., Gibson, I. W., Kraus, E., Liapis, H., Loupy, A., Nickeleit, V., Randhawa, P., Rodriguez, E. R., Rush, D., Smith, R. N., Tan, C. D., Wallace, W. D., Mengel, M.

“…The 12th Banff Conference on Allograft Pathology was held in Comandatuba, Brazil, from August 19–23, 2013, and was preceded by a 2‐day Latin American Symposium…”
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CD57+ CD4 T Cells Underlie Belatacept‐Resistant Allograft Rejection by Espinosa, J., Herr, F., Tharp, G., Bosinger, S., Song, M., Farris, A. B., George, R., Cheeseman, J., Stempora, L., Townsend, R., Durrbach, A., Kirk, A. D.

“…Belatacept is a B7‐specific fusion protein used to prevent allograft rejection by blocking T cell costimulation. Generally efficacious, it fails to prevent…”
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Neutralizing BAFF/APRIL With Atacicept Prevents Early DSA Formation and AMR Development in T Cell Depletion Induced Nonhuman Primate AMR Model by Kwun, J., Page, E., Hong, J. J., Gibby, A., Yoon, J., Farris, A. B., Villinger, F., Knechtle, S.

“…Depletional strategies directed toward achieving tolerance induction in organ transplantation have been associated with an increased incidence and risk of…”
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Belatacept‐Resistant Rejection Is Associated With CD28+ Memory CD8 T Cells by Mathews, D. V., Wakwe, W. C., Kim, S. C., Lowe, M. C., Breeden, C., Roberts, M. E., Farris, A. B., Strobert, E. A., Jenkins, J. B., Larsen, C. P., Ford, M. L., Townsend, R., Adams, A. B.

“…Recently, newer therapies have been designed to more specifically target rejection in an effort to improve efficacy and limit unwanted toxicity. Belatacept, a…”
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Banff Fibrosis Study: Multicenter Visual Assessment and Computerized Analysis of Interstitial Fibrosis in Kidney Biopsies by Farris, A. B., Chan, S., Climenhaga, J., Adam, B., Bellamy, C. O. C., Serón, D., Colvin, R. B., Reeve, J., Mengel, M.

“…Increasing interstitial fibrosis (IF) in native and kidney transplant biopsies is associated with functional decline and serves as a clinical trial end point…”
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Lessons Learned: Early Termination of a Randomized Trial of Calcineurin Inhibitor and Corticosteroid Avoidance Using Belatacept by Newell, K. A., Mehta, A. K., Larsen, C. P., Stock, P. G., Farris, A. B., Mehta, S. G., Ikle, D., Armstrong, B., Morrison, Y., Bridges, N., Robien, M., Mannon, R. B.

“…The intent of this National Institutes of Health–sponsored study was to compare a belatacept‐based immunosuppressive regimen with a maintenance regimen of…”
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Guidelines for the Diagnosis of Antibody‐Mediated Rejection in Pancreas Allografts—Updated Banff Grading Schema by Drachenberg, C. B., Torrealba, J. R., Nankivell, B. J., Rangel, E. B., Bajema, I. M., Kim, D. U., Arend, L., Bracamonte, E. R., Bromberg, J. S., Bruijn, J. A., Cantarovich, D., Chapman, J. R., Farris, A. B., Gaber, L., Goldberg, J. C., Haririan, A., Honsová, E., Iskandar, S. S., Klassen, D. K., Kraus, E., Lower, F., Odorico, J., Olson, J. L., Mittalhenkle, A., Munivenkatappa, R., Paraskevas, S., Papadimitriou, J. C., Randhawa, P., Reinholt, F. P., Renaudin, K., Revelo, P., Ruiz, P., Samaniego, M. D., Shapiro, R., Stratta, R. J., Sutherland, D. E. R., Troxell, M. L., Voska, L., Seshan, S. V., Racusen, L. C., Bartlett, S. T.

“…The first Banff proposal for the diagnosis of pancreas rejection (Am J Transplant 2008; 8: 237) dealt primarily with the diagnosis of acute T‐cell‐mediated…”
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A Pilot Trial Targeting the ICOS–ICOS‐L Pathway in Nonhuman Primate Kidney Transplantation by Lo, D. J., Anderson, D. J., Song, M., Leopardi, F., Farris, A. B., Strobert, E., Chapin, S., Devens, B., Karrer, E., Kirk, A. D.

“…Costimulation blockade with the B7‐CD28 pathway‐specific agent belatacept is now used in clinical kidney transplantation, but its efficacy remains imperfect…”
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Early barriers to neonatal porcine islet engraftment in a dual transplant model by Samy, K. P., Davis, R. P., Gao, Q., Martin, B. M., Song, M., Cano, J., Farris, A. B., McDonald, A., Gall, E. K., Dove, C. R., Leopardi, F. V., How, T., Williams, K. D., Devi, G. R., Collins, B. H., Kirk, A. D.

“…Porcine islet xenografts have the potential to provide an inexhaustible source of islets for β cell replacement. Proof‐of‐concept has been established in…”
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Belatacept and Sirolimus Prolong Nonhuman Primate Renal Allograft Survival Without a Requirement for Memory T Cell Depletion by Lo, D. J., Anderson, D. J., Weaver, T. A., Leopardi, F., Song, M., Farris, A. B., Strobert, E. A., Jenkins, J., Turgeon, N. A., Mehta, A. K., Larsen, C. P., Kirk, A. D.

“…Belatacept is an inhibitor of CD28/B7 costimulation that is clinically indicated as a calcineurin inhibitor (CNI) alternative in combination with mycophenolate…”
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Thrombalexin: Use of a Cytotopic Anticoagulant to Reduce Thrombotic Microangiopathy in a Highly Sensitized Model of Kidney Transplantation by Manook, M., Kwun, J., Burghuber, C., Samy, K., Mulvihill, M., Yoon, J., Xu, H., MacDonald, A. L., Freischlag, K., Curfman, V., Branum, E., Howell, D., Farris, A. B., Smith, R. A., Sacks, S., Dorling, A., Mamode, N., Knechtle, S. J.

“…Early activation of coagulation is an important factor in the initiation of innate immunity, as characterized by thrombotic microangiopathy (TMA). In…”
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