Search Results - "Farrington, Lila A."

Opsonized antigen activates Vδ2+ T cells via CD16/FCγRIIIa in individuals with chronic malaria exposure by Farrington, Lila A, Callaway, Perri C, Vance, Hilary M, Baskevitch, Kayla, Lutz, Emma, Warrier, Lakshmi, McIntyre, Tara I, Budker, Rachel, Jagannathan, Prasanna, Nankya, Felistas, Musinguzi, Kenneth, Nalubega, Mayimuna, Sikyomu, Ester, Naluwu, Kate, Arinaitwe, Emmanuel, Dorsey, Grant, Kamya, Moses R, Feeney, Margaret E

“…Vγ9Vδ2 T cells rapidly respond to phosphoantigens produced by Plasmodium falciparum in an innate-like manner, without prior antigen exposure or processing. Vδ2…”
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Malaria and Early Life Immunity: Competence in Context by Callaway, Perri C, Farrington, Lila A, Feeney, Margaret E

“…Childhood vaccines have been the cornerstone tool of public health over the past century. A major barrier to neonatal vaccination is the "immaturity" of the…”
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The Development of Plasmodium falciparum -Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission by Boyle, Michelle J, Jagannathan, Prasanna, Bowen, Katherine, McIntyre, Tara I, Vance, Hilary M, Farrington, Lila A, Schwartz, Alanna, Nankya, Felistas, Naluwu, Kate, Wamala, Samuel, Sikyomu, Esther, Rek, John, Greenhouse, Bryan, Arinaitwe, Emmanuel, Dorsey, Grant, Kamya, Moses R, Feeney, Margaret E

“…Cytokine-producing CD4 T cells have important roles in immunity against malaria. However, the factors influencing functional differentiation of specific CD4 T…”
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Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria by Boyle, Michelle J, Jagannathan, Prasanna, Farrington, Lila A, Eccles-James, Ijeoma, Wamala, Samuel, McIntyre, Tara I, Vance, Hilary M, Bowen, Katherine, Nankya, Felistas, Auma, Ann, Nalubega, Mayimuna, Sikyomu, Esther, Naluwu, Kate, Rek, John, Katureebe, Agaba, Bigira, Victor, Kapisi, James, Tappero, Jordan, Muhindo, Mary K, Greenhouse, Bryan, Arinaitwe, Emmanuel, Dorsey, Grant, Kamya, Moses R, Feeney, Margaret E

“…FoxP3+ regulatory CD4 T cells (Tregs) help to maintain the delicate balance between pathogen-specific immunity and immune-mediated pathology. Prior studies…”
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Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure by Jagannathan, Prasanna, Lutwama, Fredrick, Boyle, Michelle J., Nankya, Felistas, Farrington, Lila A., McIntyre, Tara I., Bowen, Katherine, Naluwu, Kate, Nalubega, Mayimuna, Musinguzi, Kenneth, Sikyomu, Esther, Budker, Rachel, Katureebe, Agaba, Rek, John, Greenhouse, Bryan, Dorsey, Grant, Kamya, Moses R., Feeney, Margaret E.

“…Vδ2 + γδ T cells are semi-innate T cells that expand markedly following P. falciparum (Pf) infection in naïve adults, but are lost and become dysfunctional…”
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Competition for antigen at the level of the APC is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection by Farrington, Lila A, Smith, Tameka A, Grey, Finn, Hill, Ann B, Snyder, Christopher M

“…The unique ability of CMV to drive the expansion of virus-specific T cell populations during the course of a lifelong, persistent infection has generated…”
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Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood by Farrington, Lila A., Jagannathan, Prasanna, McIntyre, Tara I., Vance, Hilary M., Bowen, Katherine, Boyle, Michelle J., Nankya, Felistas, Wamala, Samuel, Auma, Ann, Nalubega, Mayimuna, Sikyomu, Esther, Naluwu, Kate, Bigira, Victor, Kapisi, James, Dorsey, Grant, Kamya, Moses R., Feeney, Margaret E.

“…γδ T cells expressing Vδ2 may be instrumental in the control of malaria, because they inhibit the replication of blood-stage parasites in vitro and expand…”
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Effective Antimalarial Chemoprevention in Childhood Enhances the Quality of CD4⁺ T Cells and Limits Their Production of Immunoregulatory Interleukin 10 by Jagannathan, Prasanna, Bowen, Katherine, Nankya, Felistas, McIntyre, Tara I., Auma, Ann, Wamala, Samuel, Sikyomu, Esther, Naluwu, Kate, Nalubega, Mayimuna, Boyle, Michelle J., Farrington, Lila A., Bigira, Victor, Kapisi, James, Aweeka, Fran, Greenhouse, Bryan, Kamya, Moses, Dorsey, Grant, Feeney, Margaret E.

“…Background. Experimental inoculation of viable Plasmodium falciparum sporozoites administered with chemoprevention targeting blood-stage parasites results in…”
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Effector Phenotype of Plasmodium falciparum-Specific CD4⁺ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations by Boyle, Michelle J., Jagannathan, Prasanna, Bowen, Katherine, McIntyre, Tara I., Vance, Hilary M., Farrington, Lila A., Greenhouse, Bryan, Nankya, Felistas, Rek, John, Katureebe, Agaba, Arinaitwe, Emmanuel, Dorsey, Grant, Kamya, Moses R., Feeney, Margaret E.

“…Background. Mechanisms mediating immunity to malaria remain unclear, but animal data and experimental human vaccination models suggest a critical role for CD4⁺…”
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Evaluation of SARS-CoV-2 serology assays reveals a range of test performance by Whitman, Jeffrey D., Hiatt, Joseph, Mowery, Cody T., Shy, Brian R., Yu, Ruby, Yamamoto, Tori N., Rathore, Ujjwal, Goldgof, Gregory M., Whitty, Caroline, Woo, Jonathan M., Gallman, Antonia E., Miller, Tyler E., Levine, Andrew G., Nguyen, David N., Bapat, Sagar P., Balcerek, Joanna, Bylsma, Sophia A., Lyons, Ana M., Li, Stacy, Wong, Allison Wai-yi, Gillis-Buck, Eva Mae, Steinhart, Zachary B., Lee, Youjin, Apathy, Ryan, Lipke, Mitchell J., Smith, Jennifer Anne, Zheng, Tina, Boothby, Ian C., Isaza, Erin, Chan, Jackie, Acenas, Dante D., Lee, Jinwoo, Macrae, Trisha A., Kyaw, Than S., Wu, David, Ng, Dianna L., Gu, Wei, York, Vanessa A., Eskandarian, Haig Alexander, Callaway, Perri C., Warrier, Lakshmi, Moreno, Mary E., Levan, Justine, Torres, Leonel, Farrington, Lila A., Loudermilk, Rita P., Koshal, Kanishka, Zorn, Kelsey C., Garcia-Beltran, Wilfredo F., Yang, Diane, Astudillo, Michael G., Bernstein, Bradley E., Gelfand, Jeffrey A., Ryan, Edward T., Charles, Richelle C., Iafrate, A. John, Lennerz, Jochen K., Miller, Steve, Chiu, Charles Y., Stramer, Susan L., Wilson, Michael R., Manglik, Aashish, Ye, Chun Jimmie, Krogan, Nevan J., Anderson, Mark S., Cyster, Jason G., Ernst, Joel D., Wu, Alan H. B., Lynch, Kara L., Bern, Caryn, Hsu, Patrick D., Marson, Alexander

“…Appropriate use and interpretation of serological tests for assessments of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, infection and…”
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Opsonized antigen activates V[delta]2+ T cells via CD16/FC[gamma]RIIIa in individuals with chronic malaria exposure by Farrington, Lila A, Callaway, Perri C, Vance, Hilary M, Baskevitch, Kayla, Lutz, Emma, Warrier, Lakshmi, McIntyre, Tara I, Budker, Rachel, Jagannathan, Prasanna, Nankya, Felistas, Musinguzi, Kenneth, Nalubega, Mayimuna, Sikyomu, Ester, Naluwu, Kate, Arinaitwe, Emmanuel, Dorsey, Grant, Kamya, Moses R, Feeney, Margaret E

“…V[gamma]9V[delta]2 T cells rapidly respond to phosphoantigens produced by Plasmodium falciparum in an innate-like manner, without prior antigen exposure or…”
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Test performance evaluation of SARS-CoV-2 serological assays by Whitman, Jeffrey D., Hiatt, Joseph, Mowery, Cody T., Shy, Brian R., Yu, Ruby, Yamamoto, Tori N., Rathore, Ujjwal, Goldgof, Gregory M., Whitty, Caroline, Woo, Jonathan M., Gallman, Antonia E., Miller, Tyler E., Levine, Andrew G., Nguyen, David N., Bapat, Sagar P., Balcerek, Joanna, Bylsma, Sophia A., Lyons, Ana M., Li, Stacy, Wong, Allison Wai-yi, Gillis-Buck, Eva Mae, Steinhart, Zachary B., Lee, Youjin, Apathy, Ryan, Lipke, Mitchell J., Smith, Jennifer Anne, Zheng, Tina, Boothby, Ian C., Isaza, Erin, Chan, Jackie, Acenas, Dante D., Lee, Jinwoo, Macrae, Trisha A., Kyaw, Than S., Wu, David, Ng, Dianna L., Gu, Wei, York, Vanessa A., Eskandarian, Haig Alexander, Callaway, Perri C., Warrier, Lakshmi, Moreno, Mary E., Levan, Justine, Torres, Leonel, Farrington, Lila A., Loudermilk, Rita, Koshal, Kanishka, Zorn, Kelsey C., Garcia-Beltran, Wilfredo F., Yang, Diane, Astudillo, Michael G., Bernstein, Bradley E., Gelfand, Jeffrey A., Ryan, Edward T., Charles, Richelle C., Iafrate, A. John, Lennerz, Jochen K., Miller, Steve, Chiu, Charles Y., Stramer, Susan L., Wilson, Michael R., Manglik, Aashish, Ye, Chun Jimmie, Krogan, Nevan J., Anderson, Mark S., Cyster, Jason G., Ernst, Joel D., Wu, Alan H. B., Lynch, Kara L., Bern, Caryn, Hsu, Patrick D., Marson, Alexander

“…Appropriate use and interpretation of serological tests for assessments of SARS-CoV-2 exposure, infection and potential immunity require accurate assay…”
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Competition for antigen at the level of the antigen presenting cell is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection by Farrington, Lila A., Smith, Tameka A., Grey, Finn, Hill, Ann B., Snyder, Christopher M.

“…Cytomegalovirus’s (CMV’s) unique ability to drive the expansion of virus-specific T-cell populations over the course of a lifelong, persistent infection has…”
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Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria: e1005041 by Boyle, Michelle J, Jagannathan, Prasanna, Farrington, Lila A, Eccles-James, Ijeoma, Wamala, Samuel, McIntyre, Tara I, Vance, Hilary M, Bowen, Katherine, Nankya, Felistas, Auma, Ann, Nalubega, Mayimuna, Sikyomu, Esther, Naluwu, Kate, Rek, John, Katureebe, Agaba, Bigira, Victor, Kapisi, James, Tappero, Jordan, Muhindo, Mary K, Greenhouse, Bryan, Arinaitwe, Emmanuel, Dorsey, Grant, Kamya, Moses R, Feeney, Margaret E

“…FoxP3+ regulatory CD4 T cells (Tregs) help to maintain the delicate balance between pathogen-specific immunity and immune-mediated pathology. Prior studies…”
Get full text