Search Results - "Farrer, David G."

Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk by Lehmann, Geniece M., Verner, Marc-André, Luukinen, Bryan, Henning, Cara, Assimon, Sue Anne, LaKind, Judy S., McLanahan, Eva D., Phillips, Linda J., Davis, Matthew H., Powers, Christina M., Hines, Erin P., Haddad, Sami, Longnecker, Matthew P., Poulsen, Michael T., Farrer, David G., Marchitti, Satori A., Tan, Yu-Mei, Swartout, Jeffrey C., Sagiv, Sharon K., Welsh, Clement, Campbell, Jerry L., Foster, Warren G., Yang, Raymond S. H., Fenton, Suzanne E., Tornero-Velez, Rogelio, Francis, Bettina M., Barnett, John B., El-Masri, Hisham A., Simmons, Jane Ellen

“…Abstract Lipophilic persistent environmental chemicals (LPECs) have the potential to accumulate within a woman's body lipids over the course of many years…”
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Reduction of myeloid suppressor cell derived nitric oxide provides a mechanistic basis of lead enhancement of alloreactive CD4 + T cell proliferation by Farrer, David G., Hueber, Sara, Laiosa, Michael D., Eckles, Kevin G., McCabe, Michael J.

“…The persistent environmental toxicant and immunomodulator, lead (Pb), has been proposed to directly target CD4 + T cells. However, our studies suggest that CD4…”
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Lead enhances CD4 + T cell proliferation indirectly by targeting antigen presenting cells and modulating antigen-specific interactions by Farrer, David G., Hueber, Sara M., McCabe, Michael J.

“…Although Pb is a well-known immunotoxicant, its mechanism of action is not well understood. Low levels of Pb (∼1 μM) markedly enhance the proliferative T cell…”
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Target cells and key mediators in lead-induced immune modulation by Farrer, David G

“…Lead (Pb), is a widely dispersed and persistent environmental contaminant. It is toxic to many organ systems including the immune system. Mechanisms underlying…”
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