A comparison of two mathematical models of the impact of mass drug administration on the transmission and control of schistosomiasis

Highlights • This paper compares two mathematical models describing the transmission dynamics of schistosome infection and the impact of mass drug administration. • The models differ structurally in a number of ways, including the dynamics of the intermediate snail host and the treatment of adult wo...

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Bibliographic Details
Published in:	Epidemics Vol. 18; no. C; pp. 29 - 37
Main Authors:	Truscott, J.E, Gurarie, D, Alsallaq, R, Toor, J, Yoon, N, Farrell, S.H, Turner, H.C, Phillips, A.E, Aurelio, H.O, Ferro, J, King, C.H, Anderson, R.M
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-03-2017 Elsevier
Subjects:	Anthelmintics - therapeutic use Humans Infectious Disease Internal Medicine Mass Drug Administration Mathematical modelling Models, Theoretical Neglected tropical diseases Prevalence Schistosomiasis Schistosomiasis - prevention & control Schistosomiasis - transmission Neglected tropical diseases Schistosomiasis Mathematical modelling Mass drug administration
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Summary:	Highlights • This paper compares two mathematical models describing the transmission dynamics of schistosome infection and the impact of mass drug administration. • The models differ structurally in a number of ways, including the dynamics of the intermediate snail host and the treatment of adult worms within the human host. • The models are validated against data taken from a mass-drug administration trial in Mozambique. • The differences between the model predictions and the data are discussed in the context of the structural differences between the models.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1755-4365 1878-0067
DOI:	10.1016/j.epidem.2017.02.003