Search Results - "Farrell, Mark"
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Microbial functional diversity and carbon use feedback in soils as affected by heavy metals
Published in Environment international (01-04-2019)“…Soil microorganisms are an important indicator of soil fertility and health. However, our state of knowledge about soil microbial activities, community…”
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2
The Road to Structurally Defined β‐Glucans
Published in Chemical record (01-11-2021)“…β‐glucans are polymers of glucose that have been isolated from a variety of organisms. Isolated β‐glucans have been used for medical purposes for centuries;…”
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Lectin Drug Conjugates Targeting High Mannose N‐Glycans
Published in Chembiochem : a European journal of chemical biology (06-10-2022)“…Cancer‐associated alterations to glycosylation have been shown to aid cancer development and progression. An increased abundance of high mannose N‐glycans has…”
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4
Directing CAR NK Cells via the Metabolic Incorporation of CAR Ligands into Malignant Cell Glycans
Published in ACS chemical biology (17-06-2022)“…The abundance of sialic acid-containing glycans in the glycocalyx of malignant cells enables immune evasion. Here, we leverage the biosynthetic pathways that…”
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Microbial community structure mediates response of soil C decomposition to litter addition and warming
Published in Soil biology & biochemistry (01-01-2015)“…Microbial activity has been highlighted as one of the main unknowns controlling the fate and turnover of soil organic matter (SOM) in response to climate…”
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6
Multivalent Scaffolds to Promote B cell Tolerance
Published in Molecular pharmaceutics (07-08-2023)“…Autoimmune diseases are characterized by aberrant immune responses toward self-antigens. Current treatments lack specificity, promoting adverse effects by…”
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Functionalized High Mannose‐Specific Lectins for the Discovery of Type I Mannosidase Inhibitors
Published in Angewandte Chemie International Edition (25-05-2021)“…An engineered cyanovirin‐N homologue that exhibits specificity for high mannose N‐glycans has been constructed to aid type I α 1,2‐mannosidase inhibitor…”
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Use of composts in the remediation of heavy metal contaminated soil
Published in Journal of hazardous materials (15-03-2010)“…High levels of heavy metals in soil can ultimately lead to pollution of drinking water and contamination of food. Consequently, sustainable remediation…”
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CD22L Conjugation to Insulin Attenuates Insulin-Specific B Cell Activation
Published in Bioconjugate chemistry (15-11-2023)“…Pancreatic islet-reactive B lymphocytes promote Type 1 diabetes (T1D) by presenting an antigen to islet-destructive T cells. Teplizumab, an anti-CD3…”
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10
Space-time mapping of soil organic carbon stock and its local drivers: Potential for use in carbon accounting
Published in Geoderma (01-01-2024)“…•SOC stock trend and drivers assessed with space–time model and interpretive ML.•Australia was a net sink of SOC stocks but loss in the montane region is…”
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11
The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions
Published in Nature communications (19-10-2017)“…The entry of HIV-1 into target cells is mediated by the viral envelope glycoproteins (Env). Binding to the CD4 receptor triggers a cascade of conformational…”
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Growing soil organic carbon in dryland agricultural systems
Published in Microbiology Australia (01-01-2023)“…Soil organic carbon (SOC) plays a crucial role in dryland agricultural systems, improving resilience, productivity and delivering a range of ecosystem services…”
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Influence of mineral characteristics on the retention of low molecular weight organic compounds: A batch sorption–desorption and ATR-FTIR study
Published in Journal of colloid and interface science (15-10-2014)“…[Display omitted] •Organic acids sorption–desorption to minerals were examined by batch experiments.•Interaction mechanisms were evaluated using ATR-FTIR…”
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14
Consistent effects of biodiversity loss on multifunctionality across contrasting ecosystems
Published in Nature ecology & evolution (01-02-2018)“…Understanding how loss of biodiversity affects ecosystem functioning, and thus the delivery of ecosystem goods and services, has become increasingly necessary…”
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Elf3 deficiency during zebrafish development alters extracellular matrix organization and disrupts tissue morphogenesis
Published in PloS one (16-11-2022)“…E26 transformation specific (ETS) family transcription factors are expressed during embryogenesis and are involved in various cellular processes such as…”
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Determination of Bio-Based Fertilizer Composition Using Combined NIR and MIR Spectroscopy: A Model Averaging Approach
Published in Sensors (Basel, Switzerland) (08-08-2022)“…Application of bio-based fertilizers is considered a practical solution to enhance soil fertility and maintain soil quality. However, the composition of…”
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17
Stoichiometric controls upon low molecular weight carbon decomposition
Published in Soil biology & biochemistry (01-12-2014)“…Soil carbon (C) and nitrogen (N) cycles are inextricably linked, yet the impacts of N availability upon soil C sequestration and turnover are poorly…”
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The Bacterial Microbiome Associated With Arid Biocrusts and the Biogeochemical Influence of Biocrusts Upon the Underlying Soil
Published in Frontiers in microbiology (23-09-2019)“…Biocrusts are aggregated crusts that exist on the soil surface of arid environments. They are complex microbial communities comprised of cyanobacteria,…”
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Periodic acid–Schiff’s reagent assay for carbohydrates in a microtiter plate format
Published in Analytical biochemistry (01-09-2011)“…Microtiter plate colorimetric assays are widely used for analysis of carbohydrates and glycoconjugates. However, mucins are often not easily detected, as they…”
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Photoassimilated carbon allocation in a wheat plant-soil system as affected by soil fertility and land-use history
Published in Plant and soil (01-10-2014)“…BACKGROUND AND AIMS: Carbon (C) cycling in terrestrial ecosystems is influenced by the distribution of photo-assimilated C in the plant-soil system…”
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