Search Results - "Farrell, Kristen B"

Bisphosphonate conjugation for bone specific drug targeting by Farrell, Kristen B., Karpeisky, Alexander, Thamm, Douglas H., Zinnen, Shawn

“…Bones provide essential functions and are sites of unique biochemistry and specialized cells, but can also be sites of disease. The treatment of bone disorders…”
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VDX-111 targets proliferative pathways in canine cancer cell lines by Farrell, Kristen B, Das, Sunetra, Nordeen, Steven K, Lambert, James R, Thamm, Douglas H

“…VDX-111 (also identified as AMPI-109) is a vitamin D derivative which has shown anticancer activity. To further assess the function of this compound against…”
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Novel function of a dynein light chain in actin assembly during clathrin-mediated endocytosis by Farrell, Kristen B, McDonald, Seth, Lamb, Andrew K, Worcester, Colette, Peersen, Olve B, Di Pietro, Santiago M

“…Clathrin- and actin-mediated endocytosis is essential in eukaryotic cells. In this study, we demonstrate that Tda2 is a novel protein of the endocytic…”
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Gemcitabine–Ibandronate Conjugate Enables the Bone-Targeted Combination Therapy in Bone Cancer: Synthesis and Efficacy in Combination with Docetaxel by Farrell, Kristen B, Zinnen, Shawn, Thamm, Douglas H, Karpeisky, Alexander

“…Patients with cancer-induced bone disease, including primary bone cancers such as osteosarcoma (OS) and metastases from other tissues of origin, present a high…”
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New Regulators of Clathrin-Mediated Endocytosis Identified in Saccharomyces cerevisiae by Systematic Quantitative Fluorescence Microscopy by Farrell, Kristen B, Grossman, Caitlin, Di Pietro, Santiago M

“…Despite the importance of clathrin-mediated endocytosis (CME) for cell biology, it is unclear if all components of the machinery have been discovered and many…”
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A Second Las17 Monomeric Actin‐Binding Motif Functions in Arp2/3‐Dependent Actin Polymerization During Endocytosis by Feliciano, Daniel, Tolsma, Thomas O., Farrell, Kristen B., Aradi, Al, Di Pietro, Santiago M.

“…During clathrin‐mediated endocytosis (CME), actin assembly provides force to drive vesicle internalization. Members of the Wiskott–Aldrich syndrome protein…”
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Abstract 6233: Omacetaxine reduces c-MYC expression and demonstrates antitumor effects in osteosarcoma by Farrell, Kristen B., Thamm, Douglas H.

“…Omacetaxine mepesuccinate (OMX), also known as homoharringtonine, is a protein translation inhibitor approved for use in chronic myeloid leukemia. Recent…”
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VDX-111 targets proliferative pathways in canine cancer cell lines by Kristen B. Farrell, Sunetra Das, Steven K. Nordeen, James R. Lambert, Douglas H. Thamm

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A systematic review of the evidence for central nervous system plasticity in animal models of inflammatory-mediated gastrointestinal pain by Farrell, Kristen E, Keely, Simon, Graham, Brett A, Callister, Robin, Callister, Robert J

“…Abdominal pain frequently accompanies inflammatory disorders of the gastrointestinal tract (GIT), and animal models of GIT inflammation have been developed to…”
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