Search Results - "Farre, Magi"
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Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial
Published in Lancet neurology (01-07-2016)“…Summary Background Early cognitive intervention is the only routine therapeutic approach used for amelioration of intellectual deficits in individuals with…”
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Hydroxychloroquine for Early Treatment of Adults With Mild Coronavirus Disease 2019: A Randomized, Controlled Trial
Published in Clinical infectious diseases (06-12-2021)“…Abstract Background No effective treatments for coronavirus disease 2019 (COVID-19) exist. We aimed to determine whether early treatment with…”
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Mephedrone (4-methylmethcathinone; ‘meow meow’): chemical, pharmacological and clinical issues
Published in Psychopharmacologia (01-04-2011)“…Background Recently, those substances deriving from the active ingredient of the Khat plant, cathinone, have been rising in popularity. Indeed,…”
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Effects of cannabis exposure in the prenatal and adolescent periods: Preclinical and clinical studies in both sexes
Published in Frontiers in neuroendocrinology (01-04-2020)“…•Developing brain is particularly vulnerable to cannabis-induced effects.•Prenatal cannabis exposure: Risk of growth restriction and altered…”
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Neuropsychiatric and General Interactions of Natural and Synthetic Cannabinoids with Drugs of Abuse and Medicines
Published in CNS & neurological disorders drug targets (01-01-2017)“…Cannabis is the most widely used illicit drug. The two most important natural cannabinoids are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The…”
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6
Untargeted Metabolomics in Doping Control: Detection of New Markers of Testosterone Misuse by Ultrahigh Performance Liquid Chromatography Coupled to High-Resolution Mass Spectrometry
Published in Analytical chemistry (Washington) (18-08-2015)“…The use of untargeted metabolomics for the discovery of markers is a promising and virtually unexplored tool in the doping control field. Hybrid quadrupole…”
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Challenges encountered in the enantioselective analysis of new psychoactive substances exemplified by clephedrone (4-CMC)
Published in Journal of pharmaceutical and biomedical analysis (15-09-2024)“…In this study we report on efforts to develop an enantioselective method for the detection of the drug of abuse clephedrone…”
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Psychopathological symptoms associated with synthetic cannabinoid use: a comparison with natural cannabis
Published in Psychopharmacology (01-09-2019)“…Background Synthetic cannabinoids (SCs) are a class of new psychoactive substances that have been rapidly evolving around the world throughout recent years…”
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Daidzein modulates cocaine-reinforcing effects and cue-induced cocaine reinstatement in CD-1 male mice
Published in Psychopharmacology (01-07-2021)“…ABSTRACT Rationale Cocaine addiction is a chronic relapsing disorder that lacks of an effective treatment. Isoflavones are a family of compounds present in…”
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No evidence that MDMA-induced enhancement of emotional empathy is related to peripheral oxytocin levels or 5-HT1a receptor activation
Published in PloS one (27-06-2014)“…The present study aimed at investigating the effect of MDMA on measures of empathy and social interaction, and the roles of oxytocin and the 5-HT1A receptor in…”
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MDMA interactions with pharmaceuticals and drugs of abuse
Published in Expert opinion on drug metabolism & toxicology (03-05-2020)“…: MDMA (3,4-methylenedioxymethamphetamine), a synthetic ring-substituted amphetamine, has become one of the most widely used recreational psychostimulant drugs…”
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A phase 1, randomized double-blind, placebo controlled trial to evaluate safety and efficacy of epigallocatechin-3-gallate and cognitive training in adults with Fragile X syndrome
Published in Clinical nutrition (Edinburgh, Scotland) (01-02-2020)“…Despite the wide spectrum of experimental compounds tested in clinical trials, there is still no proven pharmacological treatment available for Fragile-X…”
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Efficacy of antidepressants in substance use disorders with and without comorbid depression A systematic review and meta-analysis
Published in Drug and alcohol dependence (04-04-2005)“…Antidepressants are commonly used in substance abusers due to the potential effect on some underlying mechanisms involved in drug use disorders and to treat…”
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Concurrent Use of Cannabis and Alcohol: Neuropsychiatric Effect Consequences
Published in CNS & neurological disorders drug targets (01-01-2017)“…Concurrent use of cannabis and alcohol is frequent. According different studies, the prevalence is among 20-34% depending on different samples studied. In…”
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The Shipibo Ceremonial Use of Ayahuasca to Promote Well-Being: An Observational Study
Published in Frontiers in pharmacology (05-05-2021)“…Promoting well-being is one of the main goals to improve health in the world. We examined the well-being and quality of life over the course of one year in a…”
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Facial emotion processing in patients with social anxiety disorder and Williams–Beuren syndrome: an fMRI study
Published in Journal of psychiatry & neuroscience (01-05-2016)“…Background Social anxiety disorder (SAD) and Williams–Beuren syndrome (WBS) are 2 conditions with major differences in terms of genetics, development and…”
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Identification of budesonide metabolites in human urine after oral administration
Published in Analytical and bioanalytical chemistry (01-08-2012)“…Budesonide (BUD) is a glucocorticoid widely used for the treatment of asthma, rhinitis, and inflammatory bowel disease. Its use in sport competitions is…”
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Urinary profile of methylprednisolone and its metabolites after oral and topical administrations
Published in The Journal of steroid biochemistry and molecular biology (01-11-2013)“…•A method to quantify methylprednisolone (MP) in urine was validated.•Fifteen metabolites of MP were also qualitatively determined with this method.•Topical…”
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Gamma-hydroxybutyrate (GHB) in humans: pharmacodynamics and pharmacokinetics
Published in Annals of the New York Academy of Sciences (01-08-2006)“…Despite gamma-hydroxybutyrate (GHB) therapeutic uses and the increasing concern about its toxicity, few studies have addressed GHB dose-related effects under…”
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Analysis of the Adherence and Safety of Second Oral Glucose-Lowering Therapy in Routine Practice From the Mediterranean Area: A Retrospective Cohort Study
Published in Frontiers in endocrinology (Lausanne) (14-07-2021)“…The aims of our study was compare adherence measured by the medical possession ratio (MPR), time until discontinuation and describe adverse events after adding…”
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