Search Results - "Farrar, L. L."

The role of IL-6 and STAT3 in inflammation and cancer by Hodge, David R., Hurt, Elaine M., Farrar, William L.

“…The defense of the host from foreign pathogens is the commonly accepted function of the vertebrate immune system. A complex system consisting of many differing…”
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Probing Magnetic Exchange Interactions with Helium by Trainer, C., Yim, C. M., Heil, C., Farrar, L. S., Tsurkan, V., Loidl, A., Wahl, P.

“…Controlling and sensing spin polarization of electrons forms the basis of spintronics. Here, we report a study of the effect of helium on the spin polarization…”
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EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis by Crea, Francesco, Fornaro, Lorenzo, Bocci, Guido, Sun, Lei, Farrar, William L., Falcone, Alfredo, Danesi, Romano

“…Tumor angiogenesis and metastatic spreading are two highly interconnected phenomena, which contribute to cancer-associated deaths. Thus, the identification of…”
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Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer by Crea, Francesco, Watahiki, Akira, Quagliata, Luca, Xue, Hui, Pikor, Larissa, Parolia, Abhijit, Wang, Yuwei, Lin, Dong, Lam, Wan L, Farrar, William L, Isogai, Takao, Morant, Rudolf, Castori-Eppenberger, Serenella, Chi, Kim N, Wang, Yuzhuo, Helgason, Cheryl D

“…Metastatic prostate cancer (PCa) is still an incurable disease. Long non-coding RNAs (lncRNAs) may be an overlooked source of cancer biomarkers and therapeutic…”
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Observing the Suppression of Superconductivity in RbEuFe4As4 by Correlated Magnetic Fluctuations by Collomb, D, Bending, S J, Koshelev, A E, Smylie, M P, Farrar, L, Bao, J-K, Chung, D Y, Kanatzidis, M G, Kwok, W-K, Welp, U

“…In this Letter, we describe quantitative magnetic imaging of superconducting vortices in RbEuFe4As4 in order to investigate the unique interplay between the…”
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Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer by Crea, Francesco, Hurt, Elaine M, Mathews, Lesley A, Cabarcas, Stephanie M, Sun, Lei, Marquez, Victor E, Danesi, Romano, Farrar, William L

“…Polycomb repressive complex 2 (PRC2) mediates gene silencing through histone H3K27 methylation. PRC2 components are over-expressed in metastatic prostate…”
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CD44 CD24 prostate cells are early cancer progenitor stem cells that provide a model for patients with poor prognosis by Hurt, E M, Kawasaki, B T, Klarmann, G J, Thomas, S B, Farrar, W L

“…Recent evidence supports the hypothesis that cancer stem cells are responsible for tumour initiation and formation. Using flow cytometry, we isolated a…”
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Systematic Review and Meta-Analysis of the Efficacy and Effectiveness of Pneumococcal Vaccines in Adults by Farrar, Jennifer L, Childs, Lana, Ouattara, Mahamoudou, Akhter, Fahmina, Britton, Amadea, Pilishvili, Tamara, Kobayashi, Miwako

“…New pneumococcal conjugate vaccines (PCVs), 15- and 20-valent (PCV15 and PCV20), have been licensed for use among U.S. adults based on safety and…”
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The emerging role of histone lysine demethylases in prostate cancer by Crea, Francesco, Sun, Lei, Mai, Antonello, Chiang, Yan Ting, Farrar, William L, Danesi, Romano, Helgason, Cheryl D

“…Early prostate cancer (PCa) is generally treatable and associated with good prognosis. After a variable time, PCa evolves into a highly metastatic and…”
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Cancer stem cells, CD200 and immunoevasion by Kawasaki, Brian T, Farrar, William L

“…The limited success seen in cancer immunotherapy signifies that an alternative approach is required. Advances in cancer biology have identified a biologically…”
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Genomic profiling of tumor initiating prostatospheres by Duhagon, Maria Ana, Hurt, Elaine M, Sotelo-Silveira, Jose R, Zhang, Xiaohu, Farrar, William L

“…The cancer stem cell (CSC) hypothesis proposes that a population of tumor cells bearing stem cell properties is responsible for the origin and maintenance of…”
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Clinical significance of Polycomb gene expression in brain tumors by Crea, Francesco, Hurt, Elaine M, Farrar, William L

“…Polycomb group (PcG) proteins are crucial for neural cancer stem cell (NCSC) self-renewal. However, the relative expression levels of PcG genes in different…”
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Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation by HODGE, David R, BENJAMIN PENG, CHERRY, James C, HURT, Elaine M, FOX, Stephen D, KELLEY, James A, MUNROE, David J, FARRAR, William L

“…A strong association exists between states of chronic inflammation and cancer, and it is believed that mediators of inflammation may be responsible for this…”
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Activation of Signal Transducer and Activator of Transcription 3 through a Phosphomimetic Serine 727 Promotes Prostate Tumorigenesis Independent of Tyrosine 705 Phosphorylation by QIN, Haiyan R, KIM, Han-Jong, JLIM, Joon-Young, HURT, Elaine M, KLARMANN, George J, KAWASAKI, Brian T, DUHAGON SERRAT, Maria A, FARRAR, William L

“…Aberrantly activated signal transducer and activator of transcription 3 (Stat3) is implicated in the development of various human cancers. Y705 phosphorylation…”
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Gossypol induces apoptosis by activating p53 in prostate cancer cells and prostate tumor-initiating cells by Volate, Suresh R, Kawasaki, Brian T, Hurt, Elaine M, Milner, John A, Kim, Young S, White, Jeffrey, Farrar, William L

“…Prostate cancer continues to represent a burgeoning medical problem in the United States. Recent studies suggest that gossypol, a bioactive phytochemical…”
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Epigenetic gene silencing in the Wnt pathway in breast cancer by Klarmann, George J., Decker, Amy, Farrar, William L.

“…Breast cancer is one of the most common malignancies in women. Despite advances in treatment of endocrine-dependent tumors, the complete molecular basis of…”
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Measurement of the absolute Raman scattering cross sections of sulfur and the standoff Raman detection of a 6-mm-thick sulfur specimen at 1500 m by Aggarwal, R. L., Farrar, L. W., Polla, D. L.

“…The absolute Raman scattering cross sections (σRS) for the 471, 217, and 153 cm−1 modes of sulfur were measured as 6.0 ± 1.2 × 10−27, 7.7 ± 1.6 × 10−27, and…”
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Interleukin 6 activates androgen receptor-mediated gene expression through a signal transducer and activator of transcription 3-dependent pathway in LNCaP prostate cancer cells by TAOSHENG CHEN, LI HUA WANG, FARRAR, W. L

“…Interleukin 6 (IL-6) is a cytokine that regulates not only immune and inflammatory responses but also the growth of some tumors, including prostate carcinomas…”
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Epidemiology and risk factors for pneumonia severity and mortality in Bangladeshi children <5 years of age before 10-valent pneumococcal conjugate vaccine introduction by Saha, Shampa, Hasan, Md, Kim, Lindsay, Farrar, Jennifer L, Hossain, Belal, Islam, Maksuda, Ahmed, Asm Nawshad Uddin, Amin, M Ruhul, Hanif, Mohammed, Hussain, Manzoor, El-Arifeen, Shams, Whitney, Cynthia G, Saha, Samir K

“…Pneumonia is the leading infectious cause of morbidity and mortality in young children in Bangladesh. We present the epidemiology of pneumonia in Bangladeshi…”
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An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patients by Crea, F., Fornaro, L., Paolicchi, E., Masi, G., Frumento, P., Loupakis, F., Salvatore, L., Cremolini, C., Schirripa, M., Graziano, F., Ronzoni, M., Ricci, V., Farrar, W.L., Falcone, A., Danesi, R.

“…Despite therapeutic innovations, metastatic colorectal cancer (mCRC) is still characterized by poor prognosis and few molecular markers predict the risk of…”
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