Search Results - "Farrall, Andrew"

Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis by Farrall, Andrew J, Wardlaw, Joanna M

“…Abstract Cerebral “microvascular” disease occurs in lacunar stroke, leukoaraiosis, vascular dementia and Alzheimer's disease. It may arise from or contribute…”
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Automatic segmentation of white matter hyperintensities from brain magnetic resonance images in the era of deep learning and big data – A systematic review by Balakrishnan, Ramya, Valdés Hernández, Maria del C., Farrall, Andrew J.

“…•Systematic literature search from 2015 to July 2020.•Only 8/37 studies made publicly available their methods.•10/37 studies proposed unsupervised segmentation…”
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Design of Novel Reconfigurable Reflectarrays With Single-Bit Phase Resolution for Ku-Band Satellite Antenna Applications by Zhang, Ming-Tao, Gao, Steven, Jiao, Yong-Chang, Wan, Ji-Xiang, Tian, Bu-Ning, Wu, Chun-Bang, Farrall, Andrew-John

“…Reconfigurable reflectarray antennas operating in Ku-band are presented in this paper. First, a novel multilayer unit-cell based on polarization turning…”
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Blood–brain barrier permeability in Alzheimer's disease: a case–control MRI study by Starr, John M, Farrall, Andrew J, Armitage, Paul, McGurn, Brian, Wardlaw, Joanna

“…Abstract Blood-brain barrier (BBB) dysfunction may contribute to the risk of Alzheimer's disease (AD). Dynamic contrast-enhanced magnetic resonance imaging…”
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A prospective, multicentre study to investigate the efficacy, safety and tolerability of octreotide LAR® (long-acting repeatable octreotide) in the primary therapy of patients with acromegaly by Mercado, Moises, Borges, Fatima, Bouterfa, Hakim, Chang, Tien-Chun, Chervin, Alberto, Farrall, Andrew J., Patocs, Attila, Petersenn, Stephan, Podoba, Jan, Safari, Mitra, Wardlaw, Joanna

“…Summary Objective  To evaluate the efficacy, safety and tolerability of octreotide LAR® (long‐acting repeatable octreotide) in the primary therapy of…”
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Clinical diagnosis of TIA or minor stroke and prognosis in patients with neurological symptoms: A rapid access clinic cohort by Graham, Catriona, Bailey, David, Hart, Simon, Hutchison, Aidan, Sandercock, Peter, Doubal, Fergus, Sudlow, Cathie, Farrall, Andrew, Wardlaw, Joanna, Dennis, Martin, Whiteley, William

“…The long-term risk of stroke or myocardial infarction (MI) in patients with minor neurological symptoms who are not clinically diagnosed with transient…”
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Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke by Mair, Grant, von Kummer, Rüdiger, Adami, Alessandro, White, Philip M, Adams, Matthew E, Yan, Bernard, Demchuk, Andrew M, Farrall, Andrew J, Sellar, Robin J, Sakka, Eleni, Palmer, Jeb, Perry, David, Lindley, Richard I, Sandercock, Peter A.G, Wardlaw, Joanna M

“…BACKGROUND AND PURPOSE—Computed tomographic angiography and magnetic resonance angiography are used increasingly to assess arterial patency in patients with…”
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A large web-based observer reliability study of early ischaemic signs on computed tomography. The Acute Cerebral CT Evaluation of Stroke Study (ACCESS) by Wardlaw, Joanna M, von Kummer, Rüdiger, Farrall, Andrew J, Chappell, Francesca M, Hill, Michael, Perry, David

“…Early signs of ischaemic stroke on computerised tomography (CT) scanning are subtle but CT is the most widely available diagnostic test for stroke. Scoring…”
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Octreotide LAR vs. surgery in newly diagnosed patients with acromegaly: a randomized, open-label, multicentre study by Colao, Annamaria, Cappabianca, Paolo, Caron, Philippe, De Menis, Ernesto, Farrall, Andrew J., Gadelha, Monica R., Hmissi, Abdel, Rees, Aled, Reincke, Martin, Safari, Mitra, T'Sjoen, Guy, Bouterfa, Hakim, Cuneo, Ross C.

“…Summary Objective  This prospective randomized study evaluated the efficacy and safety of octreotide LAR vs. surgery in newly diagnosed acromegalic patients…”
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Effect of Right Insular Involvement on Death and Functional Outcome After Acute Ischemic Stroke in the IST-3 Trial (Third International Stroke Trial) by Sposato, Luciano A, Cohen, Geoffrey, Wardlaw, Joanna M, Sandercock, Peter, Lindley, Richard I, Hachinski, Vladimir, von Kummer, Rudiger, von Heijne, Anders, Bradey, Nick, Peeters, Andre, Cala, Lesley, Adami, Alessandro, Morris, Zoe, Farrall, Andrew, Potter, Gillian

“…BACKGROUND AND PURPOSE—In patients with acute ischemic stroke, whether involvement of the insular cortex influences outcome is controversial. Much of the…”
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Switching patients with acromegaly from octreotide to pasireotide improves biochemical control: crossover extension to a randomized, double-blind, Phase III study by Bronstein, Marcello D, Fleseriu, Maria, Neggers, Sebastian, Colao, Annamaria, Sheppard, Michael, Gu, Feng, Shen, Chiung-Chyi, Gadelha, Mônica, Farrall, Andrew J, Hermosillo Reséndiz, Karina, Ruffin, Matthieu, Chen, YinMiao, Freda, Pamela

“…Many patients with acromegaly do not achieve biochemical control with first-generation somatostatin analogues. A large, multicenter, randomized, Phase III core…”
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Effect of IV alteplase on the ischemic brain lesion at 24–48 hours after ischemic stroke by Mair, Grant, von Kummer, Rüdiger, Morris, Zoe, von Heijne, Anders, Bradey, Nick, Cala, Lesley, Peeters, André, Farrall, Andrew J, Adami, Alessandro, Potter, Gillian, Sandercock, Peter A.G, Lindley, Richard I, Wardlaw, Joanna M

“…OBJECTIVETo determine whether alteplase alters the development of ischemic lesions on brain imaging after stroke. METHODSThe Third International Stroke Trial…”
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Use of dynamic contrast-enhanced MRI to measure subtle blood–brain barrier abnormalities by Armitage, Paul A, Farrall, Andrew J, Carpenter, Trevor K, Doubal, Fergus N, Wardlaw, Joanna M

“…Abstract There is growing interest in investigating the role of subtle changes in blood–brain barrier (BBB) function in common neurological disorders and the…”
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Effect of alteplase on the CT hyperdense artery sign and outcome after ischemic stroke by Mair, Grant, von Kummer, Rüdiger, Morris, Zoe, von Heijne, Anders, Bradey, Nick, Cala, Lesley, Peeters, André, Farrall, Andrew J, Adami, Alessandro, Potter, Gillian, Cohen, Geoff, Sandercock, Peter A.G, Lindley, Richard I, Wardlaw, Joanna M

“…OBJECTIVE:To investigate whether the location and extent of the CT hyperdense artery sign (HAS) at presentation affects response to IV alteplase in the…”
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Hemispheric association and dissociation of voice and speech information processing in stroke by Jones, Anna B., Farrall, Andrew J., Belin, Pascal, Pernet, Cyril R.

“…As we listen to someone speaking, we extract both linguistic and non-linguistic information. Knowing how these two sets of information are processed in the…”
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Association between systolic blood pressure variability and severity of cerebral amyloid angiopathy in incident intracerebral hemorrhage by Moullaali, Tom J., Walters, Rachel, Rodrigues, Mark, Samarasekera, Neshika, Bernal, Jose, Wang, Xia, Humphreys, Catherine, Wardlaw, Joanna M., Farrall, Andrew, Smith, Colin, Anderson, Craig S., Al-Shahi Salman, Rustam, McKinstry, Brian

“…Introduction The role of systolic blood pressure (SBP) variability in the pathogenesis of cerebral amyloid angiopathy (CAA) as an underlying cause of…”
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Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial by Mair, Grant, von Kummer, Rüdiger, Adami, Alessandro, White, Philip M., Adams, Matthew E., Yan, Bernard, Demchuk, Andrew M., Farrall, Andrew J., Sellar, Robin J., Ramaswamy, Rajesh, Mollison, Daisy, Boyd, Elena V., Rodrigues, Mark A., Samji, Karim, Baird, Andrew J., Cohen, Geoff, Sakka, Eleni, Palmer, Jeb, Perry, David, Lindley, Richard, Sandercock, Peter A. G., Wardlaw, Joanna M.

“…Introduction CT angiography (CTA) is often used for assessing patients with acute ischaemic stroke. Only limited observer reliability data exist. We tested…”
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Long-term efficacy and safety of subcutaneous pasireotide in acromegaly: results from an open-ended, multicenter, Phase II extension study by Petersenn, Stephan, Farrall, Andrew J., Block, Christophe, Melmed, Shlomo, Schopohl, Jochen, Caron, Philippe, Cuneo, Ross, Kleinberg, David, Colao, Annamaria, Ruffin, Matthieu, Hermosillo Reséndiz, Karina, Hughes, Gareth, Hu, Ke, Barkan, Ariel

“…Pasireotide has a broader somatostatin receptor binding profile than other somatostatin analogues. A 16-week, Phase II trial showed that pasireotide may be an…”
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Changes in Background Blood-Brain Barrier Integrity Between Lacunar and Cortical Ischemic Stroke Subtypes by WARDLAW, Joanna M, FARRALL, Andrew, ARMITAGE, Paul A, CARPENTER, Trevor, CHAPPELL, Francesca, DOUBAL, Fergus, CHOWDHURY, Debashish, CVORO, Vera, DENNIS, Martin S

“…Lacunar stroke is associated with endothelial dysfunction and histologically with intrinsic cerebral microvascular disease of unknown cause. Endothelial…”
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Hyperdense artery sign, symptomatic infarct swelling and effect of alteplase in acute ischaemic stroke by Wu, Simiao, Mair, Grant, Cohen, Geoff, Morris, Zoe, von Heijne, Anders, Bradey, Nick, Cala, Lesley, Peeters, Andre, Farrall, Andrew J, Adami, Alessandro, Potter, Gillian, Liu, Ming, Lindley, Richard I, Sandercock, Peter A G, Wardlaw, Joanna M

“…BackgroundAlteplase improves functional outcomes of patients with acute ischaemic stroke, but its effects on symptomatic infarct swelling, an adverse…”
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