Search Results - "Farrés, J"

PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors by Farrés, J, Llacuna, L, Martin-Caballero, J, Martínez, C, Lozano, J J, Ampurdanés, C, López-Contreras, A J, Florensa, L, Navarro, J, Ottina, E, Dantzer, F, Schreiber, V, Villunger, A, Fernández-Capetillo, O, Yélamos, J

“…Erythropoiesis is a tightly regulated process in which multipotential hematopoietic stem cells produce mature red blood cells. Here we show that deletion of…”
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Medium- and short-chain dehydrogenase/reductase gene and protein families: Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism [electronic resource] by Parés, X, Farrés, J, Kedishvili, N, Duester, G

“…Retinoic acid (RA), the most active retinoid, is synthesized in two steps from retinol. The first step, oxidation of retinol to retinaldehyde, is catalyzed by…”
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Differential Th1/Th2 cytokine patterns in chronic arthritis: interferon γ is highly expressed in synovium of rheumatoid arthritis compared with seronegative spondyloarthropathies by Cañete, Juan D, Martínez, Susana E, Farrés, Jaume, Sanmartí, Raimon, Blay, Maite, Gómez, Antoni, Salvador, Georgina, Muñoz-Gómez, José

“…OBJECTIVE To investigate possible differences in Th1 and Th2 cytokine mRNA expression in the synovial tissue (ST) of patients with rheumatoid arthritis (RA)…”
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Human and yeast ζ-crystallins bind AU-rich elements in RNA by Fernández, M. R, Porté, S, Crosas, E, Barberà, N, Farrés, J, Biosca, J. A, Parés, X

“…ζ-crystallins constitute a family of proteins with NADPH:quinone reductase activity found initially in mammalian lenses but now known to be present in many…”
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Alcohol dehydrogenase 2 is a major hepatic enzyme for human retinol metabolism by Hellgren, M, Strömberg, P, Gallego, O, Martras, S, Farrés, J, Persson, B, Parés, X, Höög, J. -O

“…The metabolism of all-trans- and 9-cis-retinol/ retinaldehyde has been investigated with focus on the activities of human, mouse and rat alcohol dehydrogenase…”
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Functional impact of treatment with ranibizumab under a reactive strategy in patients with neovascular age-related macular degeneration by Gallego-Pinazo, R, Dolz-Marco, R, Andreu-Fenoll, M, Farrés, J, Monclús, L

“…Abstract Objective To analyze the functional recovery using a pro re nata (PRN) dosing strategy with intravitreal injections of ranibizumab for patients with…”
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Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family by Duester, Gregg, Farrés, Jaume, Felder, Michael R, Holmes, Roger S, Höög, Jan-Olov, Parés, Xavier, Plapp, Bryce V, Yin, Shih-Jiun, Jörnvall, Hans

“…The alcohol dehydrogenase (ADH) gene family encodes enzymes that metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols,…”
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Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism by Parés, X., Farrés, J., Kedishvili, N., Duester, G.

“…Retinoic acid (RA), the most active retinoid, is synthesized in two steps from retinol. The first step, oxidation of retinol to retinaldehyde, is catalyzed by…”
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Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase by FARRES, J, XINPING WANG, TAKAHASHI, K, CUNNINGHAM, S. J, WANG, T. T, WEINER, H

“…Many Oriental people possess a liver mitochondrial aldehyde dehydrogenase where glutamate at position 487 has been replaced by a lysine, and they have very low…”
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Impacto funcional del tratamiento con ranibizumab bajo una estrategia reactiva en pacientes con degeneración macular asociada a la edad exudativa neovascular by Gallego-Pinazo, R, Dolz-Marco, R, Andreu-Fenoll, M, Farrés, J, Monclús, L

“…Resumen Objetivo Conocer el porcentaje de recuperación funcional, según estrategia pro re nata (PRN) con inyecciones intravítreas con ranibizumab en pacientes…”
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Molecular basis for differential substrate specificity in class IV alcohol dehydrogenases: a conserved function in retinoid metabolism but not in ethanol oxidation by Crosas, B, Allali-Hassani, A, Martínez, S E, Martras, S, Persson, B, Jörnvall, H, Parés, X, Farrés, J

“…Mammalian class IV alcohol dehydrogenase enzymes are characteristic of epithelial tissues, exhibit moderate to high K(m) values for ethanol, and are very…”
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Targeted expression of a synthetic codon optimized gene, encoding the spruce budworm antifreeze protein, leads to accumulation of antifreeze activity in the apoplasts of transgenic tobacco by Holmberg, Niklas, Farrés, Judith, Bailey, James E, Kallio, Pauli T

“…A synthetic gene based on the primary sequence of the mature spruce budworm antifreeze protein (sbwAFP) was constructed by primer overlap extension. The amino…”
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A Vertebrate Aldo-keto Reductase Active with Retinoids and Ethanol by Crosas, Bernat, Cederlund, Ella, Torres, Dámaso, Jörnvall, Hans, Farrés, Jaume, Parés, Xavier

“…Enzymes of the short chain and medium chain dehydrogenase/reductase families have been demonstrated to participate in the oxidoreduction of ethanol and…”
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Experimental design: a useful tool for PCR Optimization by Boleda, M D, Briones, P, Farrés, J, Tyfield, L, Pi, R

“…Because of complex interactions among the components of PCR and the wide and increasing variety of applications in which this technique is used, optimization…”
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Purification and characterization of a DNA-binding heterodimer of 52 and 100 kDa from HeLa cells by WEI-WEI ZHANG, LI-XIN ZHANG, BUSCH, R. K, FARRES, J, BUSCH, H

“…In studies of protein binding to the upstream region of the human proliferation-associated antigen p120 gene, a heterodimer of 52 and 100 kDa proteins was…”
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Error-prone PCR of Vitreoscilla hemoglobin (VHb) to support the growth of microaerobic Escherichia coli by Andersson, Charlotte I.J., Holmberg, Niklas, Farrés, Judith, Bailey, James E., Bülow, Leif, Kallio, Pauli T.

“…Expression of the gene encoding bacterial hemoglobin (VHb) from Vitreoscilla has been previously used to improve recombinant cell growth and enhance product…”
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Alcohol dehydrogenase of human and rat blood vessels: Role in ethanol metabolism by Allali-Hassani, Abdellah, Martı́nez, Susana E, Peralba, Josep M, Vaglenova, Julia, Vidal, Francesc, Richart, Cristóbal, Farrés, Jaume, Parés, Xavier

“…Alcohol dehydrogenase (ADH) activity has been detected in all arteries and veins examined from humans and rat. In distinct human autopsy vessels, activity…”
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Mammalian Class IV Alcohol Dehydrogenase (Stomach Alcohol Dehydrogenase): Structure, Origin, and Correlation with Enzymology by Pares, Xavier, Cederlund, Ella, Moreno, Alberto, Hjelmqvist, Lars, Farres, Jaume, Jornvall, Hans

“…The structure of a mammalian class IV alcohol dehydrogenase has been determined by peptide analysis of the protein isolated from rat stomach. The structure…”
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N-terminal acetylation in a third protein family of vertebrate alcohol dehydrogenase/retinal reductase found through a 'proteomics' approach in enzyme characterization by Hirschberg, D, Cederlund, E, Crosas, B, Jonsson, A, Tryggvason, S, Farrés, J, Parés, X, Bergman, T, Jörnvall, H

“…A recent finding of a novel class of retinol-active alcohol dehydrogenase (ADH) in frog prompted analysis of this activity in other vertebrate forms…”
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Structural and Enzymatic Properties of a Gastric NADP(H)- dependent and Retinal-active Alcohol Dehydrogenase by Peralba, Josep Maria, Cederlund, Ella, Crosas, Bernat, Moreno, Alberto, Julià, Pere, Martínez, Susana Eva, Persson, Bengt, Farrés, Jaume, Parés, Xavier, Jörnvall, Hans

“…A class IV-type, gastric alcohol dehydrogenase (ADH) has been purified from frog (Rana perezi) tissues, meaning detection of this enzyme type also in…”
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