Search Results - "Farràs, Mercè"

Homogeneous antibody-drug conjugates: DAR 2 anti-HER2 obtained by conjugation on isolated light chain followed by mAb assembly by Farràs, Mercè, Miret, Joan, Camps, Marc, Román, Ramón, Martínez, Óscar, Pujol, Xavier, Erb, Stéphane, Ehkirch, Anthony, Cianferani, Sarah, Casablancas, Antoni, Cairó, Jordi Joan

“…Despite advances in medical care, cancer remains a major threat to human health. Antibody-drug conjugates (ADCs) are a promising targeted therapy to overcome…”
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Heavy chain dimers stabilized by disulfide bonds are required to promote in vitro assembly of trastuzumab by Farràs, Mercè, Román, Ramón, Camps, Marc, Miret, Joan, Martínez, Óscar, Pujol, Xavier, Casablancas, Antoni, Cairó, Jordi Joan

“…Monoclonal antibodies (mAbs) and their derivatives have become one of the most important classes of therapeutic drugs. Their multiple applications increased…”
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Insight on the Impact of the Reduction Step on the Site‐Directed Conjugation of an Anti‐HER2 Cysteine‐Engineered Antibody by Miret, Joan, Camps, Marc, Farràs, Mercè, Román, Ramón, Erb, Stéphane, Cianferani, Sarah, Casablancas, Antoni, Cairó, Jordi J.

“…Cysteine‐based conjugation is one of the main antibody conjugation strategies for generating both heterogeneous and homogeneous Antibody Drug Conjugates…”
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Homogeneous antibody-drug conjugates: DAR 2 anti-HER2 obtained by conjugation on isolated light chain followed by mAb assembly by Farràs, Mercè, Miret, Joan, Camps, Marc, Román, Ramón, Martínez, Óscar, Pujol, Xavier, Erb, Stéphane, Ehkirch, Anthony, Cianferani, Sarah, Casablancas, Antoni, Cairó, Jordi Joan

“…Despite advances in medical care, cancer remains a major threat to human health. Antibody-drug conjugates (ADCs) are a promising targeted therapy to overcome…”
Get full text