Search Results - "Farr, C H"

Evaluation of the prenatal developmental toxicity of orally administered arsenic trioxide in rats by Holson, J.F, Stump, D.G, Clevidence, K.J, Knapp, J.F, Farr, C.H

“…A thorough review of the literature revealed no published repeated-dose oral developmental toxicity studies of inorganic arsenic in rats. In the present study,…”
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An assessment of the developmental toxicity of inorganic arsenic by DeSesso, JohnM, Jacobson, CatherineF, Scialli, AnthonyR, Farr, CraigH, Holson, JosephF

“…A critical analysis of the literature base regarding the reproductive and developmental toxicity of arsenic compounds, with emphasis on inorganic arsenicals,…”
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Determination of selected fate and aquatic toxicity characteristics of acrylic acid and a series of acrylic esters by Staples, C.A, Murphy, S.R, McLaughlin, J.E, Leung, H.-W, Cascieri, T.C, Farr, C.H

“…Acrylic acid, methyl acrylate, ethyl acrylate, and butyl acrylate are commercially important and widely used materials. This paper reports the results of a…”
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Absence of prenatal developmental toxicity from inhaled arsenic trioxide in rats by HOLSON, J. F, STUMP, D. G, ULRICH, C. E, FARR, C. H

“…A review of the literature revealed no published inhalational developmental toxicity studies of arsenic performed according to modern regulatory guidelines and…”
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Developmental toxicity assessment of arsenic acid in mice and rabbits by Nemec, MarkD, Holson, JosephF, Farr, CraigH, Hood, RonaldD

“…To evaluate potential effects of exposure to inorganic arsenic throughout major organogenesis, CD-1 mice and New Zealand White rabbits were gavaged with…”
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Systemic uptake of inhaled arsenic in rabbits by Beck, B D, Slayton, T M, Farr, C H, Sved, D W, Crecelius, E A, Holson, J F

“…Human occupational exposure to sufficiently high levels of arsenic in air has been associated with lung cancer, but generally not other types of cancer. Thus,…”
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Evaluation of the genotoxicity potential and chronic inhalation toxicity of 1,1-dichloro-1-fluoroethane (HCFC-141 b) by Millischer, R.-J., de Rooij, C.G., Rush, G.M., Farr, C.H., Ben-Dyke, R., Hardy, C.J., Lewis, D.J., Hodson-Walker, G.

“…A battery of in vitro and in vivo tests were conducted on HCFC-141b as a vapour. Bacterial gene mutation assays with Escherichia coli and Salmonella…”
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In-vitro contractility of rat seminiferous tubules in response to prostaglandins, cyclic GMP, testosterone and 2,4'-dibromoacetophenone by Farr, C H, Ellis, L C

“…The effects of prostaglandin (PG) F-2 alpha and E-2, cyclic GMP, testosterone and 2,4'-dibromoacetophenone (DBA) on rat seminiferous tubules in vitro were…”
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Comparative effects of single intraperitoneal or oral doses of sodium arsenate or arsenic trioxide during in utero development by Stump, D.G., Holson, J.F., Fleeman, T.L., Nemec, M.D., Farr, C.H.

“…Numerous studies have suggested that single‐day intraperitoneal (IP) injection of inorganic arsenic results in failure of neural tube closure and other…”
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Contractility of seminiferous tubules as related to sperm transport in the male by Ellis, L C, Groesbeck, M D, Farr, C H, Tesi, R J

“…The mammalian testes have several mechanisms to propel the nonmotile spermatozoa in the seminiferous tubules through the rete testis into the epididymis. These…”
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Influence of 2,5-hexanedione on rat brain amine synthesis and metabolism by Farr, C H, Aldous, C N, Sharma, R P

“…Sprague-Dawley derived rats were gavaged with daily doses of 2,5-hexanedione, a neurotoxic metabolite of both methyl n-butyl ketone and n-hexane. Seven daily…”
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Effects of leptophos on rat brain levels and turnover rates of biogenic amines and their metabolites by Aldous, C N, Farr, C H, Sharma, R P

“…Leptophos is a potent acetylcholinesterase inhibitor which causes delayed central-peripheral neuropathy. Rats were administered multiple doses of leptophos…”
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Acute, Subchronic, and Developmental Toxicity and Genotoxicity of 1,1,1-Trifluoroethane (HFC-143a) by Brock, William J., Trochimowicz, Henry J., Farr, Craig H., Millischer, Rene-Jean, Rusch, George M.

“…The toxicity potential of 1,1,1-trifluoroethane (HFC-143a), a CFC alternative, was evaluated in several acute, subchronic, and developmental toxicity studies…”
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Subchronic inhalation and oral toxicity of hydrogenated terphenyls in rats by Farr, C H, Nair, R S, Daly, I W, Terrill, J B, Johannsen, F R

“…The subchronic toxicity of a commercial blend of partially hydrogenated terphenyl was evaluated in rats by inhalation and oral routes of exposure. Animals were…”
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Appropriate use of animal models in the assessment of risk during prenatal development: An illustration using inorganic arsenic by Holson, Joseph F., Desesso, John M., Jacobson, Catherine F., Farr, Craig H.

“…Background Assessing risks to human development from chemical exposure typically requires integrating findings from laboratory animal and human studies…”
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Possible mechanisms of action of digitalis in cardiac muscle by FARR, C H

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Methylmercury induced alterations in brain amine syntheses in rats by Sharma, R P, Aldous, C N, Farr, C H

“…Male Sprague-Dawley rats were treated with a cumulative dose of 0, 5, 15 and 50 mg methylmercury/kg body weight. The doses were adequate to provide a clinical…”
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Potential teratogenicity of di-n-butyltin dichloride and other dibutyltin compounds by Farr, Craig H., Reinisch, Katharine, Holson, Joseph F., Neubert, Diether

“…The developmental toxicity of di‐n‐butyltin dichloride (DBT‐dC) was evaluated in Wistar rats following oral administration. No maternal toxicity,…”
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The Politeness of American Botanists by Kempton, J. H., Farr, Clifford H.

“…Abstract only…”
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Estimation of Multimedia Inorganic Arsenic Intake in the U.S. Population by Meacher, Dianne M., Menzel, Daniel B., Dillencourt, Michael D., Bic, Lubomir F., Schoof, Rosalind A., Yost, Lisa J., Eickhoff, Jane C., Farr, Craig H.

“…Arsenic is widely distributed in the environment by natural and human means. The potential for adverse health effects from inorganic arsenic depends on the…”
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