Search Results - "Farr, Andrew D."
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Experimental evolution reveals hidden diversity in evolutionary pathways
Published in eLife (25-03-2015)“…Replicate populations of natural and experimental organisms often show evidence of parallel genetic evolution, but the causes are unclear. The wrinkly spreader…”
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Minimal Surviving Inoculum in Collective Antibiotic Resistance
Published in mBio (25-04-2023)“…A common strategy used by bacteria to resist antibiotics is enzymatic degradation or modification. This reduces the antibiotic threat in the environment and is…”
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The Fitness of Beta-Lactamase Mutants Depends Nonlinearly on Resistance Level at Sublethal Antibiotic Concentrations
Published in mBio (27-06-2023)“…Adaptive evolutionary processes are constrained by the availability of mutations which cause a fitness benefit and together make up the fitness landscape,…”
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Population dynamics of cross-protection against β-lactam antibiotics in droplet microreactors
Published in Frontiers in microbiology (21-12-2023)“…Bacterial strains that are resistant to antibiotics may protect not only themselves, but also sensitive bacteria nearby if resistance involves antibiotic…”
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Barcoding Populations of Pseudomonas fluorescens SBW25
Published in Journal of molecular evolution (01-06-2023)“…In recent years, evolutionary biologists have developed an increasing interest in the use of barcoding strategies to study eco-evolutionary dynamics of…”
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Darwin was right: where now for experimental evolution?
Published in Current opinion in genetics & development (01-12-2017)“…Over the last two decades interest in direct realisation of evolutionary process and the possibilities presented by real time evolution experiments with…”
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Evolutionary convergence in experimental Pseudomonas populations
Published in The ISME Journal (01-03-2017)“…Model microbial systems provide opportunity to understand the genetic bases of ecological traits, their evolution, regulation and fitness contributions…”
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Identifying and tracking mobile elements in evolving compost communities yields insights into the nanobiome
Published in ISME Communications (01-12-2023)“…Microbial evolution is driven by rapid changes in gene content mediated by horizontal gene transfer (HGT). While mobile genetic elements (MGEs) are important…”
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Adaptive evolution by spontaneous domain fusion and protein relocalization
Published in Nature ecology & evolution (01-10-2017)“…Knowledge of adaptive processes encompasses understanding the emergence of new genes. Computational analyses of genomes suggest that new genes can arise by…”
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