Search Results - "Farquharson, Michael J."

Feasibility of chromium measurement in skin using a portable hand-held XRF system by Afzal, Fahad S.M., Al-Ebraheem, Alia, Chettle, David R., Desouza, Elstan D., Farquharson, Michael J., O’Meara, Joanne M., Pidruczny, Alice, Wainman, Bruce C., McNeill, Fiona E.

“…Chromium (III) is a trace mineral that plays an important role in glucose and lipid metabolism in the body, in addition to being used in clinical formulations…”
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Multivariate analysis of breast tissue using optical parameters extracted from a combined time-resolved fluorescence and diffuse reflectance system for tumor margin detection by Dao, Erica, Gohla, Gabriella, Williams, Phillip, Lovrics, Peter, Badr, Fares, Fang, Qiyin, Farrell, Thomas J., Farquharson, Michael J.

“…SignificanceBreast conservation therapy is the preferred technique for treating primary breast cancers. However, breast tumor margins are hard to determine as…”
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Advances in the histopathological characterization of breast tissue using combined X‐ray fluorescence and X‐ray diffraction data in a multivariate analysis approach by Johnston, Eric M., Dao, Erica, Farquharson, Michael J.

“…Previous studies have shown that the combination of X‐ray fluorescence and X‐ray diffraction data can be used as a histopathological characterization tool for…”
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Early regional cuprizone‐induced demyelination in a rat model revealed with MRI by Oakden, Wendy, Bock, Nicholas A., Al‐Ebraheem, Alia, Farquharson, Michael J., Stanisz, Greg J.

“…The cuprizone model of demyelination is well established in the mouse as a tool for the study of the mechanisms of both demyelination and remyelination. It is…”
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Breast tissue classification using x-ray scattering measurements and multivariate data analysis by Ryan, Elaine A, Farquharson, Michael J

“…This study utilized two radiation scatter interactions in order to differentiate malignant from non-malignant breast tissue. These two interactions were…”
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Altered transition metal homeostasis in the cuprizone model of demyelination by Moldovan, Nataliya, Al-Ebraheem, Alia, Lobo, Lianne, Park, Raina, Farquharson, Michael J, Bock, Nicholas A

“…In the cuprizone model of demyelination, the neurotoxin cuprizone is fed to mice to induce a reproducible pattern of demyelination in the brain. Cuprizone is a…”
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The classification of secondary colorectal liver cancer in human biopsy samples using angular dispersive x-ray diffraction and multivariate analysis by Theodorakou, Chrysoula, Farquharson, Michael J

“…The motivation behind this study is to assess whether angular dispersive x-ray diffraction (ADXRD) data, processed using multivariate analysis techniques, can…”
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The Identification and Differentiation of Secondary Colorectal Cancer in Human Liver Tissue Using X-ray Fluorescence, Coherent Scatter Spectroscopy, and Multivariate Analysis by Darvish-Molla, Sahar, Al-Ebraheem, Alia, Farquharson, Michael J.

“…Secondary colorectal liver cancer is the most widespread malignancy in patients with colorectal cancer. The aim of this study is to identify and differentiate…”
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Differences in iron and manganese concentration may confound the measurement of myelin from R1 and R2 relaxation rates in studies of dysmyelination by Desmond, Kimberly L., Al-Ebraheem, Alia, Janik, Rafal, Oakden, Wendy, Kwiecien, Jacek M., Dabrowski, Wojciech, Rola, Radoslaw, Geraki, Kalotina, Farquharson, Michael J., Stanisz, Greg J., Bock, Nicholas A.

“…A model of dysmyelination, the Long Evans Shaker (les) rat, was used to study the contribution of myelin to MR tissue properties in white matter. A large…”
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X-ray fluorescence measurements of arsenic micro-distribution in human nail clippings using synchrotron radiation by Gherase, Mihai R, Desouza, Elstan D, Farquharson, Michael J, McNeill, Fiona E, Kim, Chang-Yong, Fleming, David E B

“…Arsenic (As) distribution in nail clippings from three healthy human subjects was investigated using the microbeam experimental setup of the hard x-ray…”
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Altered transition metal homeostasis in mice following manganese injections for manganese-enhanced magnetic resonance imaging by Moldovan, Nataliya, Al-Ebraheem, Alia, Miksys, Nelson A., Farquharson, Michael J., Bock, Nicholas A.

“…In manganese-enhanced magnetic resonance imaging (MEMRI), the paramagnetic divalent ion of manganese (Mn 2+ ) is injected into animals to generate tissue…”
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Characterization of the depth distribution of Ca, Fe and Zn in skin samples, using synchrotron micro-x-ray fluorescence (SμXRF) to help quantify in-vivo measurements of elements in the skin by Desouza, Elstan D., Atiya, Ibrahim Abu, Al-Ebraheem, Alia, Wainman, Bruce C., Fleming, David E.B., McNeill, Fiona E., Farquharson, Michael J.

“…In vivo monitoring of trace and biometals in skin is normally quantified using phantoms that assume a constant elemental distribution within the skin. Layered…”
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The use of bio-metal concentrations correlated with clinical prognostic factors to assess human breast tissues by Al-Ebraheem, Alia, Geraki, Kalotina, Leek, Russell, Harris, Adrian L, Farquharson, Michael J

“…Worldwide, breast cancer is the most frequently diagnosed cancer in women and the leading cause of cancer death among women. The concentrations of bio‐metals…”
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evaluation study of trace element content in colorectal liver metastases and surrounding normal livers by X-ray fluorescence by Gurusamy, Kurinchi S, Farquharson, Michael J, Craig, Claire, Davidson, Brian R

“…Background Trace elements are involved in many key pathways involving cell cycle control. The levels of trace metals such as iron, copper, and zinc in…”
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Simultaneous determination of iron, copper and zinc concentrations in skin phantoms using XRF spectrometry by Bagshaw, Andrew P., Farquharson, Michael J.

“…X‐ray fluorescence analysis was used to determine the concentrations of iron, copper and zinc in skin phantoms. The system used consisted of a high‐output…”
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Subpixel Enhancement of Nonuniform Tissue (SPENT): A Novel MRI Technique for Quantifying BMD by Yiannakas, Marios C, Carmichael, David W, Farquharson, Michael J, Ordidge, Roger J

“…BMD is commonly obtained with DXA, but this is confounded by the length and composition of tissues that the X‐ray must traverse. Subpixel enhancement of…”
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The use of Compton scattering to differentiate between classifications of normal and diseased breast tissue by Ryan, Elaine A, Farquharson, Michael J, Flinton, David M

“…This study describes a technique for measuring the electron density of breast tissue utilizing Compton scattered photons. The Kalpha2 line from a tungsten…”
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The feasibility of a sensitive low-dose method for the in vivo evaluation of Fe in skin using K-shell x-ray fluorescence (XRF) by Farquharson, M J, Bradley, D A

“…An x-ray fluorescence (XRF) system designed for monitoring of skin Fe concentrations has been performance tested for use on patients treated for…”
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The use of skin Fe levels as a surrogate marker for organ Fe levels, to monitor treatment in cases of iron overload by Farquharson, M J, Bagshaw, A P, Porter, J B, Abeysinghe, R D

“…A system based on the detection of K-shell x-ray fluorescence (XRF) has been used to investigate whether a correlation exists between the concentration of iron…”
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Feasibility of a 109 Cd-based portable XRF device for measuring skin iron concentration in anaemic and β -Thalassaemic patients by Bangash, Sami Ullah Khan, McNeill, Fiona E, Farquharson, Michael J, Chettle, David R

“…Iron is an essential element vital for growth and development. The severe effects on the body due to iron deficiency or overload have prompted sustained…”
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