Search Results - "Farnell, Benjamin"

Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides by Luis, Ana S., Briggs, Jonathon, Zhang, Xiaoyang, Farnell, Benjamin, Ndeh, Didier, Labourel, Aurore, Baslé, Arnaud, Cartmell, Alan, Terrapon, Nicolas, Stott, Katherine, Lowe, Elisabeth C., McLean, Richard, Shearer, Kaitlyn, Schückel, Julia, Venditto, Immacolata, Ralet, Marie-Christine, Henrissat, Bernard, Martens, Eric C., Mosimann, Steven C., Abbott, D. Wade, Gilbert, Harry J.

“…The major nutrients available to human colonic Bacteroides species are glycans, exemplified by pectins, a network of covalently linked plant cell wall…”
Get full text

A Product Analog Bound Form of 3-Oxoadipate-enol-Lactonase (PcaD) Reveals a Multifunctional Role for the Divergent Cap Domain by Bains, Jasleen, Kaufman, Laura, Farnell, Benjamin, Boulanger, Martin J.

“…Lactones are a class of structurally diverse molecules that serve essential roles in biological processes ranging from quorum sensing to the aerobic catabolism…”
Get full text

Identification and Characterization of Binding Sites on S100A7, a Participant in Cancer and Inflammation Pathways by León, Rafael, Murray, Jill I, Cragg, Gina, Farnell, Benjamin, West, Nathan R, Pace, Tamara C. S, Watson, Peter H, Bohne, Cornelia, Boulanger, Martin J, Hof, Fraser

“…S100A7 (psoriasin) is a member of the S100 family of signaling proteins. It is implicated in and considered a therapeutic target for inflammation and cancer,…”
Get full text

Structural characterization of S100A15 reveals a novel zinc coordination site among S100 proteins and altered surface chemistry with functional implications for receptor binding by Murray, Jill I, Tonkin, Michelle L, Whiting, Amanda L, Peng, Fangni, Farnell, Benjamin, Cullen, Jay T, Hof, Fraser, Boulanger, Martin J

“…S100 proteins are a family of small, EF-hand containing calcium-binding signaling proteins that are implicated in many cancers. While the majority of human…”
Get full text

Structural and functional characterization of a triple mutant form of S100A7 defective for Jab1 binding by West, Nathan R., Farnell, Benjamin, Murray, Jill I., Hof, Fraser, Watson, Peter H., Boulanger, Martin J.

“…S100A7 (psoriasin) is a calcium‐ and zinc‐binding protein implicated in breast cancer. We have shown previously that S100A7 enhances survival mechanisms in…”
Get full text

Understanding the recognition and utilization of homogalacturonan by Bacteroides thetaiotaomicron by Farnell, Benjamin J

“…Homogalacturonan (HG) is a structural plant cell wall polysaccharide and a key source of dietary fiber. The human genome does not contain a single enzyme known…”
Get full text