Search Results - "Farnault, Laure"
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Cardiovascular Toxicity Related to Cancer Treatment: A Pragmatic Approach to the American and European Cardio-Oncology Guidelines
Published in Journal of the American Heart Association (15-09-2020)“…The considerable progress made in the field of cancer treatment has led to a dramatic improvement in the prognosis of patients with cancer. However, toxicities…”
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Clinical characteristics and outcomes of patients with haematologic malignancies and COVID-19 suggest that prolonged SARS-CoV-2 carriage is an important issue
Published in Annals of hematology (01-11-2021)“…Specificities of COVID-19 disease course in patients with haematologic malignancies are still poorly studied. So, we aimed to compare patients with…”
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The contribution of single-cell analysis of acute leukemia in the therapeutic strategy
Published in Biomarker research (27-06-2021)“…Abstract After decades during which the treatment of acute myeloblastic leukemia was limited to variations around a skeleton of cytarabine/anthracycline,…”
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High incidence of atrial fibrillation in patients treated with ibrutinib
Published in Open heart (01-05-2019)“…ObjectiveAtrial fibrillation (AF) is one of the most common side effects of ibrutinib, a drug that has dramatically improved the prognosis of chronic B-cell…”
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Successful treatment with adapted high dose methotrexate in a hemodialysis patient with primary central nervous system lymphoma: 100 mg/m2 seems sufficient
Published in Nefrología (01-03-2022)“…High dose methotrexate (HD-MTX) based chemoimmunotherapy is a central part of the standard approach to treatment of primary central nervous system lymphoma…”
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A transcriptomic signature predicting septic outcome in patients undergoing autologous stem cell transplantation
Published in Experimental hematology (01-09-2018)“…•A transcriptomic signature predicts infection in neutropenic patients.•The expression of 11 genes can be used routinely for sepsis prediction.•Early…”
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Impact of Molecular Biology in Diagnosis, Prognosis, and Therapeutic Management of BCR::ABL1 -Negative Myeloproliferative Neoplasm
Published in Cells (Basel, Switzerland) (01-01-2023)“…-negative myeloproliferative neoplasms (MPNs) include three major subgroups-polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis…”
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Hematological Malignancies Escape from NK Cell Innate Immune Surveillance : Mechanisms and Therapeutic Implications
Published in Clinical & developmental immunology (01-01-2012)“…Hematological malignancies treatment improved over the last years resulting in increased achievement of complete or partial remission, but unfortunately high…”
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CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine
Published in Blood advances (13-03-2018)“…Cytarabine (Ara-C) is the backbone of acute myeloid leukemia (AML) chemotherapy. Little is known about possible risk factors predictive for the frequent (ie,…”
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Persistence of natural killer cells with expansion of a hypofunctional CD56− CD16+ KIR+ NKG2C+ subset in a patient with atypical Janus kinase 3–deficient severe combined immunodeficiency
Published in Journal of allergy and clinical immunology (01-04-2013)“…[...]little is known about the mechanisms by which homozygous JAK3 R117C missense mutations impair JAK3 signaling in lymphocyte ontogeny to result in the…”
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Cytidine deaminase status as a marker of response to azacytidine treatment in MDS and AML patients
Published in British journal of haematology (01-11-2023)“…Summary Azacitidine (Aza) is a mainstay of treatment for patients with acute myeloid leukaemia (AML) ineligible for induction chemotherapy and other high‐risk…”
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Impact of Next-Generation Sequencing in Diagnosis, Prognosis and Therapeutic Management of Acute Myeloid Leukemia/Myelodysplastic Neoplasms
Published in Cancers (22-06-2023)“…For decades, the diagnosis, prognosis and thus, the treatment of acute myeloblastic leukemias and myelodysplastic neoplasms has been mainly based on…”
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Pharmacokinetics/pharmacodynamics of liposomal cytarabine (VYXEOS) in AML patients: Influence of cytidine deaminase genetic polymorphisms
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e19517 Background: Vyxeos is a liposomal formulation of daunorubicin and cytarabine recently approved for treating adults with newly-diagnosed…”
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Clinical, biological, electrophysiological and therapeutic profile of patients with anti-MAG neuropathy according to MYD88L265P and CXCR4 mutations and underlying haemopathy
Published in Journal of neurology (01-03-2024)“…Introduction Anti-MAG neuropathies are associated with an IgM monoclonal gammopathy of undetermined significance (MGUS) or with a malignant haemopathy. Our…”
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Faut-il prescrire des cures de consolidation aux patients avec indication d’allogreffe en première rémission complète d’une leucémie aiguë myéloïde ?
Published in Hématologie (01-03-2018)Get full text
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Significance of Measurable Residual Disease in Adult Philadelphia Chromosome-Positive ALL: A GRAAPH-2014 Study
Published in Journal of clinical oncology (10-09-2024)“…quantification is widely regarded as the standard for monitoring measurable residual disease (MRD) in Philadelphia chromosome-positive (Ph+) ALL. However,…”
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Pharmacokinetics and pharmacogenetics of liposomal cytarabine in AML patients treated with CPX-351
Published in Journal of controlled release (10-10-2021)“…CPX-351 is a liposome encapsulating cytarabine and daunorubicin for treating Acute Myeloid Leukemia (AML) patients. To what extent differences in cytidine…”
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Determination of 5-azacitidine in human plasma by LC–MS/MS: application to pharmacokinetics pilot study in MDS/AML patients
Published in Cancer chemotherapy and pharmacology (01-03-2023)“…Purpose Azacitidine (Vidaza®, AZA) is a mainstay for treating acute myeloid leukemia (AML) in patients unfit for standard induction and other myelodysplastic…”
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Successful treatment with adapted high dose methotrexate in a hemodialysis patient with primary central nervous system lymphoma: 100mg/m2 seems sufficient
Published in Nefrología (01-03-2022)“…High dose methotrexate (HD-MTX) based chemoimmunotherapy is a central part of the standard approach to treatment of primary central nervous system lymphoma…”
Get full text
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