Search Results - "Farmanbar, Amir"

Mutational signatures reveal ternary relationships between homologous recombination repair, APOBEC, and mismatch repair in gynecological cancers by Farmanbar, Amir, Firouzi, Sanaz, Kneller, Robert, Khiabanian, Hossein

“…Revealing the impacts of endogenous and exogenous mutagenesis processes is essential for understanding the etiology of somatic genomic alterations and…”
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RNA sequencing identifies clonal structure of T-cell repertoires in patients with adult T-cell leukemia/lymphoma by Farmanbar, Amir, Kneller, Robert, Firouzi, Sanaz

“…The diversity of T-cell receptor (TCR) repertoires, as generated by somatic DNA rearrangements, is central to immune system function. High-throughput…”
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Mutational signatures reveal mutual exclusivity of homologous recombination and mismatch repair deficiencies in colorectal and stomach tumors by Farmanbar, Amir, Kneller, Robert, Firouzi, Sanaz

“…Decomposing somatic mutation spectra into mutational signatures and their corresponding etiologies provides a powerful approach for investigating the mechanism…”
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Mutational Intratumor Heterogeneity is a Complex and Early Event in the Development of Adult T-cell Leukemia/Lymphoma by Farmanbar, Amir, Firouzi, Sanaz, Makałowski, Wojciech, Kneller, Robert, Iwanaga, Masako, Utsunomiya, Atae, Nakai, Kenta, Watanabe, Toshiki

“…The clonal architecture of tumors plays a vital role in their pathogenesis and invasiveness; however, it is not yet clear how this clonality contributes to…”
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Clonality of HTLV-1–infected T cells as a risk indicator for development and progression of adult T-cell leukemia by Firouzi, Sanaz, Farmanbar, Amir, Nakai, Kenta, Iwanaga, Masako, Uchimaru, Kaoru, Utsunomiya, Atae, Suzuki, Yutaka, Watanabe, Toshiki

“…Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell leukemia virus type 1 (HTLV-1) that develops along a carcinogenic process…”
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Inferring clonal structure in HTLV-1-infected individuals: towards bridging the gap between analysis and visualization by Farmanbar, Amir, Firouzi, Sanaz, Makałowski, Wojciech, Iwanaga, Masako, Uchimaru, Kaoru, Utsunomiya, Atae, Watanabe, Toshiki, Nakai, Kenta

“…Human T cell leukemia virus type 1 (HTLV-1) causes adult T cell leukemia (ATL) in a proportion of infected individuals after a long latency period. Development…”
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Multidisciplinary insight into clonal expansion of HTLV-1-infected cells in adult T-cell leukemia via modeling by deterministic finite automata coupled with high-throughput sequencing by Farmanbar, Amir, Firouzi, Sanaz, Park, Sung-Joon, Nakai, Kenta, Uchimaru, Kaoru, Watanabe, Toshiki

“…Clonal expansion of leukemic cells leads to onset of adult T-cell leukemia (ATL), an aggressive lymphoid malignancy with a very poor prognosis. Infection with…”
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The genomic landscape of metastatic histologic special types of invasive breast cancer by Pareja, Fresia, Ferrando, Lorenzo, Lee, Simon S. K., Beca, Francisco, Selenica, Pier, Brown, David N., Farmanbar, Amir, Da Cruz Paula, Arnaud, Vahdatinia, Mahsa, Zhang, Hong, Zoppoli, Gabriele, Wen, Hannah Y., Brogi, Edi, Robson, Mark E., Razavi, Pedram, Chandarlapaty, Sarat, Weigelt, Britta, Reis-Filho, Jorge S.

“…Histologic special types of breast cancer (BC) account for ~20% of BCs. Large sequencing studies of metastatic BC have focused on invasive ductal carcinomas of…”
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