Search Results - "Farley, Scotland"
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“Flash & Click”: Multifunctionalized Lipid Derivatives as Tools To Study Viral Infections
Published in Journal of the American Chemical Society (10-08-2022)“…In this perspective article, we describe the current status of lipid tools for studying host lipid–virus interactions at the cellular level. We discuss the…”
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Cannabinoids Block Cellular Entry of SARS-CoV‑2 and the Emerging Variants
Published in Journal of natural products (Washington, D.C.) (28-01-2022)“…As a complement to vaccines, small-molecule therapeutic agents are needed to treat or prevent infections by severe acute respiratory syndrome coronavirus-2…”
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A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants
Published in Nature communications (17-06-2022)“…A comprehensive understanding of host dependency factors for SARS-CoV-2 remains elusive. Here, we map alterations in host lipids following SARS-CoV-2 infection…”
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Caged lipids for subcellular manipulation
Published in Current opinion in chemical biology (01-12-2021)“…We present recently developed strategies to manipulate lipid levels in live cells by light. We focus on photoremovable protecting groups that lead to…”
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Trifunctional Sphinganine: A New Tool to Dissect Sphingolipid Function
Published in ACS chemical biology (16-02-2024)“…Functions and cell biology of the sphingolipids sphingosine and sphinganine in cells are not well understood. While some signaling roles for sphingosine have…”
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Cross-reactivity of SARS-CoV structural protein antibodies against SARS-CoV-2
Published in Cell reports (Cambridge) (16-02-2021)“…In the ongoing coronavirus disease 2019 (COVID-19) pandemic, there remain unanswered questions regarding the nature and significance of the humoral immune…”
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Genetic Tools for Studying the Roles of Sphingolipids in Viral Infections
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Sphingolipids are a critical family of membrane lipids with diverse functions in eukaryotic cells, and a growing body of literature supports that these lipids…”
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