Search Results - "Farkas, Daniel L."
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Biomedical Applications of Translational Optical Imaging: From Molecules to Humans
Published in Molecules (Basel, Switzerland) (02-11-2021)“…Light is a powerful investigational tool in biomedicine, at all levels of structural organization. Its multitude of features (intensity, wavelength,…”
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2
Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model
Published in NeuroImage (Orlando, Fla.) (01-01-2011)“…Noninvasive monitoring of β-amyloid (Aβ) plaques, the neuropathological hallmarks of Alzheimer's disease (AD), is critical for AD diagnosis and prognosis…”
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3
Tumor detection and elimination by a targeted gallium corrole
Published in Proceedings of the National Academy of Sciences - PNAS (14-04-2009)“…Sulfonated gallium(III) corroles are intensely fluorescent macrocyclic compounds that spontaneously assemble with carrier proteins to undergo cell entry. We…”
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Polarization-Sensitive Hyperspectral Imaging in vivo: A Multimode Dermoscope for Skin Analysis
Published in Scientific reports (12-05-2014)“…Attempts to understand the changes in the structure and physiology of human skin abnormalities by non-invasive optical imaging are aided by spectroscopic…”
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5
Isolation of cancer stem cells from adult glioblastoma multiforme
Published in Oncogene (16-12-2004)“…Glioblastoma multiforme (GBM) is the most common adult primary brain tumor and is comprised of a heterogeneous population of cells. It is unclear which cells…”
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Review of the potential of optical technologies for cancer diagnosis in neurosurgery: a step toward intraoperative neurophotonics
Published in Neurophotonics (Print) (01-01-2017)“…Advances in image-guided therapy enable physicians to obtain real-time information on neurological disorders such as brain tumors to improve resection…”
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7
Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9
Published in Journal of neurochemistry (01-12-2009)“…Immunization with an altered myelin-derived peptide (MOG45D) improves recovery from acute CNS insults, partially via recruitment of monocyte-derived…”
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A Mechanistic Study of Tumor-Targeted Corrole Toxicity
Published in Molecular pharmaceutics (05-12-2011)“…HerGa is a self-assembled tumor-targeted particle that bears both tumor detection and elimination activities in a single, two-component complex (Agadjanian et…”
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Induction of potent antitumor immunity by intratumoral injection of interleukin 23-transduced dendritic cells
Published in Cancer research (Chicago, Ill.) (01-09-2006)“…Dendritic cells (DCs) are potent antigen-presenting cells that play a critical role in priming immune responses to tumor. Interleukin (IL)-23 can act directly…”
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10
Multimodality imaging in vivo for preclinical assessment of tumor-targeted doxorubicin nanoparticles
Published in PloS one (03-04-2012)“…This study presents a new multimodal imaging approach that includes high-frequency ultrasound, fluorescence intensity, confocal, and spectral imaging to…”
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Endothelial Cells in Co-culture Enhance Embryonic Stem Cell Differentiation to Pancreatic Progenitors and Insulin-Producing Cells through BMP Signaling
Published in Stem cell reviews (01-09-2011)“…Endothelial cells (ECs) represent the major component of the embryonic pancreatic niche and play a key role in the differentiation of insulin-producing β cells…”
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12
Investigating photoexcitation-induced mitochondrial damage by chemotherapeutic corroles using multimode optical imaging
Published in Journal of Biomedical Optics (01-01-2012)“…We recently reported that a targeted, brightly fluorescent gallium corrole (HerGa) is highly effective for breast tumor detection and treatment. Unlike…”
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13
Quantitative and morphometric evaluation of the angiogenic effects of leptin
Published in Journal of biomedical optics (01-11-2008)“…Angiogenesis is a dynamic process that requires an interaction of pro-and antiangiogenic factors. It is known that the cytokine leptin stimulates endothelial…”
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14
Smartphone-based multispectral imaging: system development and potential for mobile skin diagnosis
Published in Biomedical optics express (01-12-2016)“…We investigate the potential of mobile smartphone-based multispectral imaging for the quantitative diagnosis and management of skin lesions. Recently, various…”
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15
Spatial Distribution of Calcium Entry Evoked by Single Action Potentials within the Presynaptic Active Zone
Published in The Journal of neuroscience (24-03-2004)“…The nature of presynaptic calcium (Ca(2+)) signals that initiate neurotransmitter release makes these signals difficult to study, in part because of the small…”
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Editorial Expression of Concern: Dynamic in vivo interactions among Myc network members
Published in Oncogene (03-11-2021)Get full text
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Separating melanin from hemodynamics in nevi using multimode hyperspectral dermoscopy and spatial frequency domain spectroscopy
Published in Journal of biomedical optics (01-11-2016)“…Changes in the pattern and distribution of both melanocytes (pigment producing) and vasculature (hemoglobin containing) are important in distinguishing…”
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Photoexcitation of tumor-targeted corroles induces singlet oxygen-mediated augmentation of cytotoxicity
Published in Journal of controlled release (10-11-2012)“…The tumor-targeted corrole particle, HerGa, displays preferential toxicity to tumors in vivo and can be tracked via fluorescence for simultaneous detection,…”
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Enhancement of axial resolution in fluorescence microscopy by standing-wave excitation
Published in Nature (London) (04-11-1993)“…The use of fluorescence microscopy for investigating the three-dimensional structure of cells and tissue is of growing importance in cell biology, biophysics…”
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3D PLGA scaffolds improve differentiation and function of bone marrow mesenchymal stem cell-derived hepatocytes
Published in Stem cells and development (01-09-2010)“…Liver tissue engineering with hepatic stem cells provides a promising alternative to liver transplantation in patients with acute and chronic hepatic failure…”
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