Search Results - "Farih‐Sips, Hetty"

Downregulation of Wnt Signaling by Increased Expression of Dickkopf‐1 and ‐2 is a Prerequisite for Late‐Stage Osteoblast Differentiation of KS483 Cells by van der Horst, Geertje, van der Werf, Steffie M, Farih‐Sips, Hetty, van Bezooijen, Rutger L, Löwik, Clemens WGM, Karperien, Marcel

“…We examined the role of Wnt/β‐catenin signaling in successive stages of osteoblast differentiation. It has been shown that Wnt signaling in mature osteoblasts…”
Get full text

Interleukin‐17: A New Bone Acting Cytokine In Vitro by Van Bezooijen, Rutger L., Farih‐Sips, Hetty C. M., Papapoulos, Socrates E., Löwik, Clemens W. G. M.

“…Interleukin‐17 (IL‐17) is a recently cloned cytokine that is exclusively produced by activated T cells, but its receptor has been found on several cells and…”
Get full text

IL‐1α, IL‐1β, IL‐6, and TNF‐α Steady‐State mRNA Levels Analyzed by Reverse Transcription‐Competitive PCR in Bone Marrow of Gonadectomized Mice by Van Bezooijen, Rutger L., Farih‐Sips, Hetty C. M., Papapoulos, Socrates E., Löwik, Clemens W. G. M.

“…Loss of gonadal function in both females and males is associated with increased rates of bone loss by a yet unidentified mechanism. There is ample evidence…”
Get full text

Multiple Mechanisms Are Involved in Inhibition of Osteoblast Differentiation by PTHrP and PTH in KS483 Cells by van der Horst, Geertje, Farih‐Sips, Hetty, Löwik, Clemens WGM, Karperien, Marcel

“…We examined the mechanism by which PTHrP and PTH inhibit KS483 osteoblastic differentiation. We show that PTHrP and PTH inhibit differentiation downstream of…”
Get full text

Full Length or Fragments in Hormone Studies? by van der Horst, Geertje, Farih‐Sips, Hetty, Löwik, Clemens WGM, Karperien, Marcel

Get full text

A Frame-Shift Mutation in the Type I Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Causing Blomstrand Lethal Osteochondrodysplasia by Karperien, Marcel, van der Harten, Hans J., van Schooten, Ron, Farih-Sips, Hetty, den Hollander, Nicolette S., Kneppers, Sander L. J., Nijweide, Peter, Papapoulos, Socrates E., Löwik, Clemens W. G. M.

“…Blomstrand osteochondrodysplasia (BOCD) is a rare lethal skeletal dysplasia characterized by accelerated endochondral and intramembranous ossification…”
Get full text

Identification of a Retinoic Acid-Inducible Element in the Murine PTH/PTHrP (Parathyroid Hormone/Parathyroid Hormone-Related Peptide) Receptor Gene by Karperien, Marcel, Farih-Sips, Hetty, Hendriks, Jeanine A.A, Lanske, Beate, Papapoulos, Socrates E, Abou-Samra, Abdul-Badi, Löwik, Clemens W.G.M, Defize, Libert H.K

“…We have shown previously that the PTH/PTHrP (PTH-related peptide) receptor mRNA becomes expressed very early in murine embryogenesis, i.e. during the formation…”
Get full text

Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells by van der Horst, Geertje, Farih-Sips, Hetty, Löwik, Clemens W.G.M, Karperien, Marcel

“…The involvement of hedgehog signaling in the initiation of osteoblastic differentiation in the bone collar during endochondral bone formation has been well…”
Get full text

Novel late response genes of PTHrP in chondrocytes by Hoogendam, Jakomijn, Farih-Sips, Hetty, van Beek, Ermond, Löwik, Clemens W G M, Wit, Jan M, Karperien, Marcel

“…To gain more insight into the downstream effectors of parathyroid hormone (PTH) related peptide (PTHrP) signaling in chondrocytes, we performed microarray…”
Get more information

Expression of the Parathyroid Hormone-Related Peptide Gene in Retinoic Acid-Induced Differentiation: Involvement of ETS and Sp1 by Karperien, Marcel, Farih-Sips, Hetty, Löwik, Clemens W.G.M, de Laat, Siegfried W, Boonstra, Johannes, Defize, Libert H.K

“…Differentiation of P19 embryonal carcinoma (EC) and embryonal stem (ES)-5 cells with retinoic acid (RA) induces expression of PTH-related peptide (PTHrP) mRNA…”
Get full text