Search Results - "Farias, Savio Torres de"
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RNP-world: The ultimate essence of life is a ribonucleoprotein process
Published in Genetics and molecular biology (01-01-2022)“…The fundamental essence of life is based on process of interaction between nucleic acids and proteins. In a prebiotic world, amino acids, peptides, ions, and…”
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Peptidyl Transferase Center and the Emergence of the Translation System
Published in Life (Basel, Switzerland) (25-04-2017)“…In this work, the three-dimensional (3D) structure of the ancestral Peptidyl Transferase Center (PTC) built by concatamers of ancestral sequences of tRNAs was…”
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From RNA to DNA: Emergence of reverse transcriptases from an ancestral RNA-dependent RNA polymerase
Published in BioSystems (01-12-2024)“…The transition from RNA as the informational molecule of primordial biological systems to the DNA genomes of modern organisms represents one of the greatest…”
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Living cognition and the nature of organisms
Published in BioSystems (01-12-2024)“…There is no consensus about what cognition is. Different perspectives conceptualize it in different ways. In the same vein, there is no agreement about which…”
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The Ancient History of Peptidyl Transferase Center Formation as Told by Conservation and Information Analyses
Published in Life (Basel, Switzerland) (05-08-2020)“…The peptidyl transferase center (PTC) is the catalytic center of the ribosome and forms part of the 23S ribosomal RNA. The PTC has been recognized as the…”
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Major evolutionary transitions before cells: A journey from molecules to organisms
Published in Progress in biophysics and molecular biology (01-09-2024)“…Basing on logical assumptions and necessary steps of complexification along biological evolution, we propose here an evolutionary path from molecules to cells…”
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Organic Codes: A Unifying Concept for Life
Published in Acta biotheoretica (01-12-2021)“…Although the knowledge about biological systems has advanced exponentially in recent decades, it is surprising to realize that the very definition of Life…”
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Origin of the 16S Ribosomal Molecule from Ancestor tRNAs
Published in Journal of molecular evolution (01-06-2021)“…We tested the hypothesis that concatemers of ancestral tRNAs gave rise to the 16S ribosomal RNA. We built an ancestral sequence of proto-tRNAs that showed a…”
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From RNA to DNA: Insights about the transition of informational molecule in the biological systems based on the structural proximity between the polymerases
Published in BioSystems (01-08-2021)“…Structural relations in an evolutionary context of polymerases is crucial to gain insights into the transition from an RNA world to a Ribonucleoprotein world…”
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Evolutionary origin of B family DNA-dependent DNA polymerases from retrotranscriptases
Published in BioSystems (01-08-2023)“…The evolution of DNA and DNA polymerases was a crucial step in the evolution of life on Earth. In the present work, we reconstruct the ancestral sequence and…”
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Conceptual challenges for the emergence of the biological system: Cell theory and self-replication
Published in Medical hypotheses (01-10-2018)“…We re-evaluate research relating to the current theories of the emergence of biological systems. The challenge being that research programmes concerning the…”
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NoRCEL's Engagement in Africa: The AstroScience Exploration Network (ASEN)
Published in Astrobiology (01-07-2023)“…The AstroScience Exploration Network (ASEN) is the latest innovative initiative from the Network of Researchers on the Chemical Emergence of Life (NoRCEL)…”
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Structural Computational Analysis of the Natural History of Class I aminoacyl-tRNA Synthetases Suggests their Role in Establishing the Genetic Code
Published in Journal of molecular evolution (01-12-2021)“…The evolutionary history of Class I aminoacyl-tRNA synthetases (aaRS) through the reconstruction of ancestral sequences is presented. From structural molecular…”
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Viruses as a survival strategy in the armory of life
Published in History and philosophy of the life sciences (01-12-2019)“…Viruses have generally been thought of as infectious agents. New data on mimivirus, however, suggests a reinterpretation of this thought. Earth's biosphere…”
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The Theory of Chemical Symbiosis: A Margulian View for the Emergence of Biological Systems (Origin of Life)
Published in Acta biotheoretica (01-03-2021)“…The theory of chemical symbiosis (TCS) suggests that biological systems started with the collaboration of two polymeric molecules existing in early Earth:…”
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Natural History of DNA-Dependent DNA Polymerases: Multiple Pathways to the Origins of DNA
Published in Viruses (01-03-2023)“…One of the major evolutionary transitions that led to DNA replacing RNA as the primary informational molecule in biological systems is still the subject of an…”
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Performance of intron 7 of the β -fibrinogen gene for phylogenetic analysis: An example using gladiator frogs, Boana Gray, 1825 (Anura, Hylidae, Cophomantinae)
Published in ZooKeys (22-02-2023)“…, the third largest genus of Hylinae, has cryptic morphological species. The potential applicability of is explored to propose a robust phylogeny of . The…”
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A Brief History of Giant Viruses' Studies in Brazilian Biomes
Published in Viruses (19-01-2022)“…Almost two decades after the isolation of the first amoebal giant viruses, indubitably the discovery of these entities has deeply affected the current…”
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Prediction of MicroRNAs in the Epstein–Barr Virus Reveals Potential Targets for the Viral Self-Regulation
Published in Indian journal of microbiology (01-03-2019)“…Studies involving miRNAs have opened discussions about their broad participation in viral infections. Regarding the Human gammaherpesvirus 4 or Epstein–Barr…”
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Structure of the genetic code suggested by the hydropathy correlation between anticodons and amino acid residues
Published in Origins of life and evolution of biospheres (01-02-2007)“…The correlation between hydropathies of anticodons and amino acids, detected by other authors utilizing scales of amino acid molecules in solution, was…”
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