Search Results - "Farias, André Borges"
-
1
Interactions between the AraC/XylS-like transcriptional activator InvF of Salmonella Typhimurium, the RNA polymerase alpha subunit and the chaperone SicA
Published in Scientific reports (02-01-2024)“…Salmonella enterica serovar Typhimurium causes gastroenteritis and systemic infections in humans. For this bacterium the expression of a type III secretion…”
Get full text
Journal Article -
2
Synthesis and Evaluation of the Anticancer and Trypanocidal Activities of Boronic Tyrphostins
Published in ChemMedChem (18-07-2018)“…Molecules containing an (cyanovinyl)arene moiety are known as tyrphostins because of their ability to inhibit proteins from the tyrosine kinase family, an…”
Get full text
Journal Article -
3
α-Glucosidase isoform G contributes to heme detoxification in Rhodnius prolixus and its knockdown affects Trypanosoma cruzi metacyclogenesis
Published in Current research in insect science (01-01-2024)“…•α-glucosidases can interact with heme according to bioinformatics and functional analysis;.•α-glucosidase isoform Rp-αGluG is involved in the hz formation…”
Get full text
Journal Article -
4
Design and Synthesis of New Anthranyl Phenylhydrazides: Antileishmanial Activity and Structure–Activity Relationship
Published in Pharmaceuticals (Basel, Switzerland) (01-08-2023)“…Leishmaniasis is a neglected tropical disease affecting millions of people worldwide. A centenary approach to antimonial-based drugs was first initiated with…”
Get full text
Journal Article -
5
Acylhydrazones as isoniazid derivatives with multi-target profiles for the treatment of Alzheimer’s disease: Radical scavenging, myeloperoxidase/acetylcholinesterase inhibition and biometal chelation
Published in Bioorganic & medicinal chemistry (15-05-2020)“…[Display omitted] Acylhydrazones 1a-o, derived from isoniazid, were synthesized and evaluated for Myeloperoxidase (MPO) and Acetylcholinesterase (AChE)…”
Get full text
Journal Article -
6
Predicting bacterial transcription factor binding sites through machine learning and structural characterization based on DNA duplex stability
Published in Briefings in bioinformatics (14-11-2024)“…Abstract Transcriptional factors (TFs) in bacteria play a crucial role in gene regulation by binding to specific DNA sequences, thereby assisting in the…”
Get full text
Journal Article