Search Results - "Faria Fonseca, Bárbara"
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Clostridium difficile toxin A attenuates Wnt/β-catenin signaling in intestinal epithelial cells
Published in Infection and immunity (01-07-2014)“…Clostridium difficile toxins A and B (TcdA and TcdB) are homologous glycosyltransferases that inhibit a group of small GTPases within host cells, but several…”
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Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids
Published in Oncogene (12-01-2024)“…Thyroid cancer is the most common endocrine malignancy and several genetic events have been described to promote the development of thyroid carcinogenesis…”
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Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism
Published in Nature communications (17-11-2022)“…The thyroid gland captures iodide in order to synthesize hormones that act on almost all tissues and are essential for normal growth and metabolism. Low plasma…”
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Single-Cell Trajectory Inference Guided Enhancement of Thyroid Maturation In Vitro Using TGF-Beta Inhibition
Published in Frontiers in endocrinology (Lausanne) (31-05-2021)“…The thyroid gland regulates metabolism and growth secretion of thyroid hormones by thyroid follicular cells (TFCs). Loss of TFCs, by cellular dysfunction,…”
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