Pulmonary sporotrichosis in immunocompetent patient: case report

The pulmonary extracutaneous form of sporotrichosis, an infection caused by genetically distinct species of a dimorphic fungus of the genus Sporothrix, is rare, with few cases reported in the literature. This is a case of a 55-year-old woman, resident of the Barreiro region in Belo Horizonte/ Minas...

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Bibliographic Details
Published in:	Revista médica de Minas Gerais Vol. 31; p. e-31415
Main Authors:	Lauar, Isabela Dias, Nascimento, Victor Adalberto Machado, Soares, José Eduardo Palacio, Matos, Marcelle Amaral, Faria, Kathleen Emerick Paiva, Nogueira, Luiz Paulo Arreguy, Parreiras, Guilherme Cardoso
Format:	Journal Article
Language:	English
Published:	Associação Médica de Minas Gerais 01-11-2021
Subjects:	fungal infection pulmonary fungal infection sporotrichosis
Online Access:	Get full text
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Summary:	The pulmonary extracutaneous form of sporotrichosis, an infection caused by genetically distinct species of a dimorphic fungus of the genus Sporothrix, is rare, with few cases reported in the literature. This is a case of a 55-year-old woman, resident of the Barreiro region in Belo Horizonte/ Minas Gerais, who sought the infectious disease service of a public hospital in Belo Horizonte with a history of weight loss, dyspnea at small efforts, chronic cough and three-year-old vespertinus chills. She was treated for bacterial pneumonia on five occasions without clinical improvement. He presented computed tomography of the chest with residual cavitation and excavated pulmonary lesions. The patient was hospitalized with dyspnea on small efforts, cough and purulent sputum, and her sputum culture was positive for Sporothrix spp. The gold standard treatment for pulmonary sporotrichosis was instituted, initially with itraconazole, 200 mg twice a day, however, after 10 months, the clinical and radiological improvement was not satisfactory and the administration of intravenous amphotericin B lipid complex 4 mg/kg/day was chosen. In less than 1 month the patient presented worsening of the condition and died, despite receiving 2g of accumulated dose of amphotericin B lipid complex.
ISSN:	0103-880X 2238-3182
DOI:	10.5935/2238-3182.2021e31415