Search Results - "Faria, Antonio Rodolfo de"
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Synthesis and biological evaluation of thiazole derivatives as LbSOD inhibitors
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2019)“…Leishmaniasis is considered as one of the major neglected tropical diseases due to its magnitude and wide geographic distribution. Leishmania braziliensis,…”
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Structure-guided discovery of thiazolidine-2,4-dione derivatives as a novel class of Leishmania major pteridine reductase 1 inhibitors
Published in European journal of medicinal chemistry (10-11-2016)“…Leishmania major, as other protozoan parasites, plague human kind since pre-historic times but it remains a worldwide ailment for which the therapeutic arsenal…”
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Evaluation of anti-inflammatory activity and molecular docking study of new aza-bicyclic isoxazoline acylhydrazone derivatives
Published in MedChemComm (01-11-2019)“…The aim of this study was to investigate the anti-inflammatory effects of two new isoxazoline-acylhydrazone derivatives: N…”
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Novel aza-bicyclic 2-isoxazoline acylhydrazone hybrids and their synergistic potential with fluconazole against a drug-resistant Candida albicans strain
Published in Brazilian journal of microbiology (01-06-2024)“…As the prevalence of drug-resistant Candida isolates continues to rise, the imperative for identifying novel compounds to enhance the arsenal of antifungal…”
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Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents
Published in Pharmaceuticals (Basel, Switzerland) (17-11-2019)“…Fourteen arylsemicarbazone derivatives were synthesized and evaluated in order to find agents with potential anticancer activity. Cytotoxic screening was…”
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Synthesis and biological evaluation of thiazole derivatives as Lb SOD inhibitors
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2019)Get full text
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Synthesis of new aza-bicyclic 2-isoxazolines by 1,3-dipolar cycloaddition of endocyclic enecarbamates and enamides with nitrile oxides
Published in Tetrahedron letters (11-02-2009)“…n = 1 or 2; R = Me, Bn; R 1 = aryl, OEt, OBn; R 2 = CO 2Et, CONH 2, aryl, 2-furfuryl. Novel aza-bicyclic 2-isoxazolines, 4,5-dihydroisoxazole[5,4-…”
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Synthesis and Antimicrobial Activities of 5-Arylidene-thiazolidine-2,4-dione Derivatives
Published in BioMed research international (01-01-2014)“…Antibiotic resistance is considered one of the world's major public health concerns. The main cause of bacterial resistance is the improper and repeated use of…”
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Síntese e avaliação preliminar da atividade antinociceptiva de novas isoxazolil-aril-hidrazonas
Published in Química Nova (2011)“…New 2-isoxazoline aldehydes were synthesized, in good yields, from cycloadduct of the 1,3-dipolar cycloaddition reaction between endocyclic enecarbamate and…”
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Evaluation of anti-inflammatory activity and molecular docking study of new aza-bicyclic isoxazoline acylhydrazone derivatives† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9md00276f
Published in MedChemComm (12-09-2019)“…The aim of this study was to investigate the anti-inflammatory effects of two new isoxazoline-acylhydrazone derivatives. The aim of this study was to…”
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Síntese e atividade antiedematogênica de derivados N-triptofil-5-benzilideno-2,4-tiazolidinadiona e N-triptofil-5-benzilideno-rodanina
Published in Química nova (01-12-2004)Get full text
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Antinociceptive Effects of Aza-Bicyclic Isoxazoline-Acylhydrazone Derivatives in Different Models of Nociception in Mice
Published in Current topics in medicinal chemistry (04-03-2022)“…In a study recently published by our research group, the isoxazoline-acylhydrazone derivatives R-99 and R-123 presented promising antinociceptive activity…”
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Síntese e atividade antiedematogênica de derivados N-triptofil-5-benzilideno-2,4-tiazolidinadiona e N-triptofil-5-benzilideno-rodanina Synthesis and antiedematogenic activity of some N-trypthophyl-5-benzylidene-2,4-thiazolidinedione and N-trypthophyl-5-benzylidene-rhodanine derivatives
Published in Química nova (01-12-2004)“…Derivatives of N-tryptophyl-5-benzylidene-2,4-thiazolidinedione (7a-c) and N-tryptophyl-5-benzylidene-rhodanine (7d-f) were prepared by condensation of the…”
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