Search Results - "Farhat, Katja"

Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling by Farhat, Katja, Riekenberg, Sabine, Heine, Holger, Debarry, Jennifer, Lang, Roland, Mages, Jörg, Buwitt‐Beckmann, Ute, Röschmann, Kristina, Jung, Günther, Wiesmüller, Karl‐Heinz, Ulmer, Artur J.

“…TLR are primary triggers of the innate immune system by recognizing various microorganisms through conserved pathogen‐associated molecular patterns. TLR2 is…”
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The stimulatory Gα(s) protein is involved in olfactory signal transduction in Drosophila by Deng, Ying, Zhang, Weiyi, Farhat, Katja, Oberland, Sonja, Gisselmann, Günter, Neuhaus, Eva M

“…Seven-transmembrane receptors typically mediate olfactory signal transduction by coupling to G-proteins. Although insect odorant receptors have seven…”
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Loss of Epithelial Hypoxia-Inducible Factor Prolyl Hydroxylase 2 Accelerates Skin Wound Healing in Mice by Kalucka, Joanna, Ettinger, Andreas, Franke, Kristin, Mamlouk, Soulafa, Singh, Rashim Pal, Farhat, Katja, Muschter, Antje, Olbrich, Susanne, Breier, Georg, Katschinski, Dörthe M., Huttner, Wieland, Weidemann, Alexander, Wielockx, Ben

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Hypoxia modulates fibroblastic architecture, adhesion and migration: a role for HIF-1α in cofilin regulation and cytoplasmic actin distribution by Vogler, Melanie, Vogel, Sabine, Krull, Sabine, Farhat, Katja, Leisering, Pia, Lutz, Susanne, Wuertz, Christina M, Katschinski, Dörthe M, Zieseniss, Anke

“…Cells can adapt to hypoxia by various mechanisms. Yet, hypoxia-induced effects on the cytoskeleton-based cell architecture and functions are largely unknown…”
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Prolyl‐4‐hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions by Swain, Lija, Wottawa, Marieke, Hillemann, Annette, Beneke, Angelika, Odagiri, Haruki, Terada, Kazutoyo, Endo, Motoyoshi, Oike, Yuichi, Farhat, Katja, Katschinski, Dörthe M.

“…PHD3 influences apoptotic cell survival decisions in macrophages by altered production of Angiopoietin‐like protein 2. On a molecular level, cells sense…”
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Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion by Rietkötter, Eva, Menck, Kerstin, Bleckmann, Annalen, Farhat, Katja, Schaffrinski, Meike, Schulz, Matthias, Hanisch, Uwe-Karsten, Binder, Claudia, Pukrop, Tobias

“…The bisphosphonate zoledronic acid (ZA) significantly reduces complications of bone metastasis by inhibiting resident macrophages, the osteoclasts. Recent…”
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Prolyl Hydroxylase Domain (PHD) 2 Affects Cell Migration and F-actin Formation via RhoA/Rho-associated Kinase-dependent Cofilin Phosphorylation by Vogel, Sabine, Wottawa, Marieke, Farhat, Katja, Zieseniss, Anke, Schnelle, Moritz, Le-Huu, Sinja, von Ahlen, Melanie, Malz, Cordula, Camenisch, Gieri, Katschinski, Dörthe M.

“…Cells are responding to hypoxia via prolyl-4-hydroxylase domain (PHD) enzymes, which are responsible for oxygen-dependent hydroxylation of the…”
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Frizzled1 is a marker of inflammatory macrophages, and its ligand Wnt3a is involved in reprogramming Mycobacterium tuberculosis-infected macrophages by Neumann, Jan, Schaale, Kolja, Farhat, Katja, Endermann, Tobias, Ulmer, Artur J, Ehlers, Stefan, Reiling, Norbert

“…Wnt/Frizzled signaling, essential for embryonic development, has also recently been implicated in the modulation of inflammatory processes. In the current…”
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Toll-like receptors in domestic animals by Jungi, Thomas W, Farhat, Katja, Burgener, Iwan A, Werling, Dirk

“…Toll-like receptors are pattern recognition receptors with which hosts recognize pathogen-associated molecular patterns (PAMP). This recognition process is…”
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The Stimulatory Gαs Protein Is Involved in Olfactory Signal Transduction in Drosophila by Deng, Ying, Zhang, Weiyi, Farhat, Katja, Oberland, Sonja, Gisselmann, Günter, Neuhaus, Eva M.

“…Seven-transmembrane receptors typically mediate olfactory signal transduction by coupling to G-proteins. Although insect odorant receptors have seven…”
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Unfavourable consequences of chronic cardiac HIF-1α stabilization by HÖLSCHER, Marion, SCHÄFER, Katrin, MAIER, Lars S, KATSCHINSKI, Dörthe M, ZIESENISS, Anke, KRULL, Sabine, FARHAT, Katja, HESSE, Amke, SITTER, Monique, YUN LIN, PICHLER, Bernd J, THISTLETHWAITE, Patricia, EL-ARMOUCHE, Ali

“…The hypoxia-inducible factor-1 (HIF-1) is the master modulator of hypoxic gene expression. The effects of chronically stabilized cardiac HIF-1α and its role in…”
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PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages by Guentsch, Annemarie, Beneke, Angelika, Swain, Lija, Farhat, Katja, Nagarajan, Shunmugam, Wielockx, Ben, Raithatha, Kaamini, Dudek, Jan, Rehling, Peter, Zieseniss, Anke, Jatho, Aline, Chong, Mei, Santos, Celio X. C., Shah, Ajay M., Katschinski, Dörthe M.

“…The prolyl-4-hydroxylase domain (PHD) enzymes are regarded as the molecular oxygen sensors. There is an interplay between oxygen availability and cellular…”
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Carcinoma cells misuse the host tissue damage response to invade the brain by Chuang, Han-Ning, van Rossum, Denise, Sieger, Dirk, Siam, Laila, Klemm, Florian, Bleckmann, Annalen, Bayerlová, Michaela, Farhat, Katja, Scheffel, Jörg, Schulz, Matthias, Dehghani, Faramarz, Stadelmann, Christine, Hanisch, Uwe-Karsten, Binder, Claudia, Pukrop, Tobias

“…The metastatic colonization of the brain by carcinoma cells is still barely understood, in particular when considering interactions with the host tissue. The…”
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Knockdown of prolyl-4-hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA-MB-231 cells by affecting TGF-[beta]1 processing by Wottawa, Marieke, Leisering, Pia, Ahlen, Melanie von, Schnelle, Moritz, Vogel, Sabine, Malz, Cordula, Bordoli, Mattia Renato, Camenisch, Gieri, Hesse, Amke, Napp, Joanna, Alves, Frauke, Kristiansen, Glen, Farhat, Katja, Katschinski, Dörthe Magdalena

“…The prolyl-4-hydroxylase domain 1-3 (PHD1-3) enzymes are regulating the protein stability of the [alpha]-subunit of the hypoxia-inducible factor-1 (HIF-1),…”
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Knockdown of prolyl‐4‐hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA‐MB‐231 cells by affecting TGF‐β1 processing by Wottawa, Marieke, Leisering, Pia, Ahlen, Melanie von, Schnelle, Moritz, Vogel, Sabine, Malz, Cordula, Bordoli, Mattia Renato, Camenisch, Gieri, Hesse, Amke, Napp, Joanna, Alves, Frauke, Kristiansen, Glen, Farhat, Katja, Katschinski, Dörthe Magdalena

“…The prolyl‐4‐hydroxylase domain 1–3 (PHD1–3) enzymes are regulating the protein stability of the α‐subunit of the hypoxia‐inducible factor‐1 (HIF‐1), which…”
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Hypoxia Modulates Fibroblastic Architecture, Adhesion and Migration: A Role for HIF-1[alpha] in Cofilin Regulation and Cytoplasmic Actin Distribution by Vogler, Melanie, Vogel, Sabine, Krull, Sabine, Farhat, Katja, Leisering, Pia, Lutz, Susanne, Wuertz, Christina M, Katschinski, Dörthe M, Zieseniss, Anke

“…Cells can adapt to hypoxia by various mechanisms. Yet, hypoxia-induced effects on the cytoskeleton-based cell architecture and functions are largely unknown…”
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The Stimulatory G[alpha].sub.s Protein Is Involved in Olfactory Signal Transduction in Drosophila by Deng, Ying, Zhang, Weiyi, Farhat, Katja, Oberland, Sonja, Gisselmann, Günter, Neuhaus, Eva M

“…Seven-transmembrane receptors typically mediate olfactory signal transduction by coupling to G-proteins. Although insect odorant receptors have seven…”
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A potential test system for detecting contaminations by bacterial lipoproteins by Farhat, Katja, Ulmer, Artur J., Jungi, Thomas W.

“…Biological specimens are often contaminated with bacteria-derived products such as LPS or lipoproteins (LP), which trigger unwanted inflammatory responses in…”
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Regulators of G-protein signalling are modulated by bacterial lipopeptides and lipopolysaccharide by Riekenberg, Sabine, Farhat, Katja, Debarry, Jennifer, Heine, Holger, Jung, Günther, Wiesmüller, Karl-Heinz, Ulmer, Artur J

“…Regulators of G-protein signalling accelerate the GTPase activity of Gα subunits, driving G proteins in their inactive GDP-bound form. This property defines…”
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Identification of full length bovine TLR1 and functional characterization of lipopeptide recognition by bovine TLR2/1 heterodimer by Farhat, Katja, Riekenberg, Sabine, Jung, Günther, Wiesmüller, Karl-Heinz, Jungi, Thomas W, Ulmer, Artur J

“…Toll-like receptors (TLR) are highly conserved pattern recognition receptors of the innate immune system. Toll-like receptor 2 (TLR2) recognizes bacterial…”
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