Search Results - "Fardella, Carlos E."

Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension by Muñoz-Durango, Natalia, Fuentes, Cristóbal A, Castillo, Andrés E, González-Gómez, Luis Martín, Vecchiola, Andrea, Fardella, Carlos E, Kalergis, Alexis M

“…Arterial hypertension is a common condition worldwide and an important predictor of several complicated diseases. Arterial hypertension can be triggered by…”
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Epigenetics and arterial hypertension: the challenge of emerging evidence by Friso, Simonetta, Carvajal, Cristian A, Fardella, Carlos E, Olivieri, Oliviero

“…Epigenetic phenomena include DNA methylation, post-translational histone modifications, and noncoding RNAs, as major marks. Although similar to genetic…”
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Computed Tomography and Adrenal Venous Sampling in the Diagnosis of Unilateral Primary Aldosteronism by Williams, Tracy A, Burrello, Jacopo, Sechi, Leonardo A, Fardella, Carlos E, Matrozova, Joanna, Adolf, Christian, Baudrand, René, Bernardi, Stella, Beuschlein, Felix, Catena, Cristiana, Doumas, Michalis, Fallo, Francesco, Giacchetti, Gilberta, Heinrich, Daniel A, Saint-Hilary, Gaëlle, Jansen, Pieter M, Januszewicz, Andrzej, Kocjan, Tomaz, Nishikawa, Tetsuo, Quinkler, Marcus, Satoh, Fumitoshi, Umakoshi, Hironobu, Widimský, Jiří, Hahner, Stefanie, Douma, Stella, Stowasser, Michael, Mulatero, Paolo, Reincke, Martin

“…Unilateral primary aldosteronism is the most common surgically correctable form of endocrine hypertension and is usually differentiated from bilateral forms by…”
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Novel metabolomic profile of subjects with non-classic apparent mineralocorticoid excess by Tapia-Castillo, Alejandra, Carvajal, Cristian A., López-Cortés, Xaviera, Vecchiola, Andrea, Fardella, Carlos E.

“…Nonclassic apparent mineralocorticoid excess (NC-AME) is proposed as a novel clinical condition with a mild phenotypic spectrum that ranges from normotension…”
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Increased Diagnosis of Primary Aldosteronism, Including Surgically Correctable Forms, in Centers from Five Continents by Mulatero, Paolo, Stowasser, Michael, Loh, Keh-Chuan, Fardella, Carlos E., Gordon, Richard D., Mosso, Lorena, Gomez-Sanchez, Celso E., Veglio, Franco, Young, William F.

“…Primary aldosteronism (PA) is a common form of endocrine hypertension previously believed to account for less than 1% of hypertensive patients. Hypokalemia was…”
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Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess by Tapia-Castillo, Alejandra, Guanzon, Dominic, Palma, Carlos, Lai, Andrew, Barros, Eric, Allende, Fidel, Vecchiola, Andrea, Fardella, Carlos E, Salomón, Carlos, Carvajal, Cristian A

“…The "nonclassic" apparent mineralocorticoid excess (NC-AME) has been identified in approximately 7% of general population. This phenotype is characterized by…”
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Serum Alpha-1-Acid Glycoprotein-1 and Urinary Extracellular Vesicle miR-21-5p as Potential Biomarkers of Primary Aldosteronism by Carvajal, Cristian A, Tapia-Castillo, Alejandra, Pérez, Jorge A, Fardella, Carlos E

“…Primary aldosteronism (PA) is the most common cause of secondary hypertension and reaches a prevalence of 6-10%. PA is an endocrine disorder, currently…”
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Aldosterone Promotes Autoimmune Damage by Enhancing Th17-Mediated Immunity by Herrada, Andres A, Contreras, Francisco J, Marini, Natacha P, Amador, Cristian A, Gonzalez, Pablo A, Cortes, Claudia M, Riedel, Claudia A, Carvajal, Cristian A, Figueroa, Fernando, Michea, Luis F, Fardella, Carlos E, Kalergis, Alexis M

“…Excessive production of aldosterone leads to the development of hypertension and cardiovascular disease by generating an inflammatory state that can be…”
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Urinary sodium-to-potassium ratio and plasma renin and aldosterone concentrations in normotensive children: implications for the interpretation of results by Martinez-Aguayo, Alejandro G., Campino, Carmen, Rodriguez-Fernandez, Maria, Poggi, Helena, D’apremont, Ivonne, Moore, Rosario, Garcia, Hernan, Solari, Sandra, Allende, Fidel, Peredo, Soledad, Trincado, Claudia, Carvajal, Cristian, Arancibia, Monica, Ossa, Jose Tomas, Sifaqui, Sofia, Fardella, Carlos E., Baudrand, Rene

“…OBJECTIVES:To identify associations among the plasma renin concentration (PRC), plasma aldosterone and urinary sodium (Na)/potassium (K) ratio, and to…”
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Eplerenone Implantation Improved Adipose Dysfunction Averting RAAS Activation and Cell Division by Vecchiola, Andrea, Fuentes, Cristóbal A, Solar, Isidora, Lagos, Carlos F, Opazo, Maria Cecilia, Muñoz-Durango, Natalia, Riedel, Claudia A, Owen, Gareth I, Kalergis, Alexis M, Fardella, Carlos E

“…Mineralocorticoid receptor (MR) activation within adipose tissue, triggers inflammation and metabolic syndrome development. The pharmacological blockade of MR…”
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Primary Aldosteronism and Hypertensive Disease by Mosso, Lorena, Carvajal, Cristian, González, Alexis, Barraza, Adolfo, Avila, Fernando, Montero, Joaquín, Huete, Alvaro, Gederlini, Alessandra, Fardella, Carlos E

“…ABSTRACT—Recent studies in hypertensive populations that have used the serum aldosterone (SA) to plasma renin activity (PRA) ratio as a screening test have…”
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Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients by STEHR, Carlos B, MELLADO, Rosemarie, FARDELLA, Carlos E, OCARANZA, Maria P, CARVAJAL, Cristian A, MOSSO, Lorena, BECERRA, Elia, SOLIS, Margarita, GARCIA, Lorena, LAVANDERO, Sergio, JALIL, Jorge

“…Patients with primary aldosteronism experience greater left ventricular hypertrophy and a higher frequency of cardiovascular events than do essential…”
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LC–MS/MS Method for the Simultaneous Determination of Free Urinary Steroids by Allende, Fidel, Solari, Sandra, Campino, Carmen, Carvajal, Cristian A., Lagos, Carlos F., Vecchiola, Andrea, Valdivia, Carolina, Baudrand, René, Owen, Gareth I., Fardella, Carlos E.

“…Cortisol homeostasis is implicated in hypertension and metabolic syndrome. Two enzymes modulate cortisol availability; 11β-hydroxysteroid dehydrogenase type 1…”
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Classic and Nonclassic Apparent Mineralocorticoid Excess Syndrome by Carvajal, Cristian A, Tapia-Castillo, Alejandra, Vecchiola, Andrea, Baudrand, Rene, Fardella, Carlos E

“…Abstract Context Arterial hypertension (AHT) is one of the most frequent pathologies in the general population. Subtypes of essential hypertension…”
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Extending the endocrine hypertension spectrum: novel nonclassic apparent mineralocorticoid excess by Carvajal, Cristian A., Tapia-Castillo, Alejandra, Fardella, Carlos E.

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Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort by Williams, Tracy A, PhD, Lenders, Jacques W M, Prof, Mulatero, Paolo, MD, Burrello, Jacopo, MD, Rottenkolber, Marietta, MS, Adolf, Christian, MD, Satoh, Fumitoshi, Prof, Amar, Laurence, MD, Quinkler, Marcus, MD, Deinum, Jaap, MD, Beuschlein, Felix, Prof, Kitamoto, Kanako K, MD, Pham, Uyen, MD, Morimoto, Ryo, MD, Umakoshi, Hironobu, MD, Prejbisz, Aleksander, MD, Kocjan, Tomaz, MD, Naruse, Mitsuhide, Prof, Stowasser, Michael, Prof, Nishikawa, Tetsuo, MD, Young, William F, Prof, Gomez-Sanchez, Celso E, Prof, Funder, John W, Prof, Reincke, Martin, Prof

“…Summary Background Although unilateral primary aldosteronism is the most common surgically correctable cause of hypertension, no standard criteria exist to…”
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Response to Associations Among Sodium Intake, Endothelial Dysfunction, and Endothelial Damage Biomarkers in Hypertension (AJH-D-18-00331) by Campino, Carmen, Baudrand, Rene, Fardella, Carlos E

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Primary Aldosteronism, Aldosterone, and Extracellular Vesicles by Carvajal, Cristian A, Tapia-Castillo, Alejandra, Pérez, Jorge A, Fardella, Carlos E

“…Primary aldosteronism (PA) is an endocrine related condition leading to arterial hypertension due to inappropriately high and unregulated aldosterone…”
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Familial hyperaldosteronism: an European Reference Network on Rare Endocrine Conditions clinical practice guideline by Mulatero, Paolo, Scholl, Ute I, Fardella, Carlos E, Charmandari, Evangelia, Januszewicz, Andrzej, Reincke, Martin, Gomez-Sanchez, Celso E, Stowasser, Michael, Dekkers, Olaf M

“…We describe herein the European Reference Network on Rare Endocrine Conditions clinical practice guideline on diagnosis and management of familial forms of…”
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Progressive 11β-Hydroxysteroid Dehydrogenase Type 2 Insufficiency as Kidney Function Declines by Uslar, Thomas, Newman, Andrew J, Tapia-Castillo, Alejandra, Carvajal, Cristian A, Fardella, Carlos E, Allende, Fidel, Solari, Sandra, Tsai, Laura C, Milks, Julia, Cherney, Michael, Stouffer, David G, Auchus, Richard, Brown, Jenifer M, Baudrand, René, Vaidya, Anand

“…It has been postulated that chronic kidney disease (CKD) is a state of relative 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2) insufficiency, resulting in…”
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