Search Results - "Farassati, Faris"
-
1
Low-dose all-trans retinoic acid enhances cytotoxicity of cisplatin and 5-fluorouracil on CD44+ cancer stem cells
Published in Biomedicine & pharmacotherapy (01-08-2015)“…Abstract Cis-diamminedichloridoplatinum(II)(CDDP)-based combination chemotherapy is frequently used in gastrointestinal cancer. The synergistic mechanism of…”
Get full text
Journal Article -
2
Colorectal Cancer in Iran: Molecular Epidemiology and Screening Strategies
Published in Journal of Cancer Epidemiology (01-01-2015)“…Purpose. The increasing incidence of colorectal cancer (CRC) in the past three decades in Iran has made it a major public health burden. This study aimed to…”
Get full text
Journal Article -
3
The Prognostic Value of Different Molecular Subtypes of Breast Cancer in Relation to Enhancer-of-Zeste Homologue 2 Expression
Published in Journal of clinical and diagnostic research (01-07-2019)“…Introduction: The role of Enhancer-of-zeste homologue 2 (EZH2) in breast cancer invasion and progression may be attributed to EZH2-mediated epigenetic…”
Get full text
Journal Article -
4
Impact of RAS/RAF mutations on clinical and prognostic outcomes in metastatic colorectal cancer
Published in Bioimpacts (01-01-2021)“…[...]it is second most common cancer in East Azerbaijan.2 Despite the longstanding screening and early detection programs as well as improvements in cancer…”
Get full text
Journal Article -
5
Utilizing ras signaling pathway to direct selective replication of herpes simplex virus-1
Published in PloS one (04-08-2009)“…Re-engineering the tropism of viruses is an attractive translational strategy for targeting cancer cells. The Ras signal transduction pathway is a central hub…”
Get full text
Journal Article -
6
Inhibition of mesothelin as a novel strategy for targeting cancer cells
Published in PloS one (02-04-2012)“…Mesothelin, a differentiation antigen present in a series of malignancies such as mesothelioma, ovarian, lung and pancreatic cancer, has been studied as a…”
Get full text
Journal Article -
7
Identifying the main barriers for participation in a population-based colorectal cancer screening programme in East Azerbaijan, Iran
Published in Ecancermedicalscience (2022)“…Colorectal cancer (CRC) is the third most common cancer and the second leading cause of death worldwide. However, CRC is considered as one of the most…”
Get full text
Journal Article -
8
Value of Enhancer of Zeste Homolog 2 (EZH2) for Determining Prognosis in Colon Cancer
Published in Journal of clinical and diagnostic research (01-03-2020)“…Introduction: It has been reported that Enhancer of Zeste Homolog 2 (EZH2) enhancer is expressed in Colorectal Cancer (CRC), but there are only limited…”
Get full text
Journal Article -
9
RalA signaling pathway as a therapeutic target in hepatocellular carcinoma (HCC)
Published in Molecular oncology (01-07-2014)“…Ral (Ras like) leads an important proto-oncogenic signaling pathway down-stream of Ras. In this work, RalA was found to be significantly overactivated in…”
Get full text
Journal Article -
10
Development and Validation of Persian Risk Assessment Tool using National Comprehensive Cancer Network Guideline for Colorectal Cancer Screening
Published in Journal of clinical and diagnostic research (2020)“…Introduction: Despite evidence that early diagnosis of Colorectal Cancer (CRC) reduces the associated death burden, screening programs are uncommon even in…”
Get full text
Journal Article -
11
Inhibition of RalA signaling pathway in treatment of non-small cell lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2012)“…Abstract Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and relatively resistant to chemotherapy. The most prevalent molecular…”
Get full text
Journal Article -
12
Ral Overactivation in Malignant Peripheral Nerve Sheath Tumors
Published in Molecular and Cellular Biology (01-07-2009)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
13
Pro-oncogenic cell signaling machinery as a target for oncolytic viruses
Published in Current pharmaceutical biotechnology (01-07-2012)“…Viruses function in close harmony with the signaling machinery of their host. Upon exposure to the cell, a battery of viral products become engaged in boosting…”
Get more information
Journal Article -
14
Gene silencing for epidermal growth factor receptor variant III induces cell-specific cytotoxicity
Published in Molecular cancer therapeutics (01-11-2008)“…Epidermal growth factor receptor variant III (EGFRvIII) is a constitutively active mutant form of EGFR that is expressed in 40% to 50% of gliomas and several…”
Get full text
Journal Article -
15
Ras pathway activation in malignant mesothelioma
Published in Journal of thoracic oncology (01-09-2007)“…Mutations in Ras family genes are rare in malignant mesothelioma. The role of activation of the Ras signaling pathway in the pathogenesis of mesothelioma is…”
Get more information
Journal Article -
16
Abstract LB-16: Inhibition of RalA as a novel strategy for targeting ovarian cancer
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Abstract: The Ral (Ras like) GTPase guanyl nucleotide-binding proteins, RalA and RalB are direct effectors of pro-oncogene Ras. RalA and RalB are…”
Get full text
Journal Article -
17
Editorial announcing PubMed indexing of Oncolytic Virotherapy
Published in Oncolytic virotherapy (01-01-2017)“…Faris Farassati1,2 1Saint Luke’s Cancer Institute-Saint Luke’s Marion Bloch Neuroscience Institute, Kansas City, MO, USA; 2Midwest Biomedical Research…”
Get full text
Journal Article -
18
Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids
Published in Oncogene (31-03-2005)“…Neurofibromatosis type 1 (NF1) is a common genetic disorder of the nervous system resulting in neurofibromas and malignant peripheral nerve sheath tumors…”
Get full text
Journal Article -
19
The role of KPNβ1 in neuro-oncology
Published in OncoTargets and therapy (10-04-2017)“…Megan Lilley,1,2 Faris Farassati1,3 1Midwest Biomedical Research Foundation, Kansas City Veterans Affairs Medical Center, 2School of Medicine, University of…”
Get full text
Journal Article -
20
The role of KPNβ 1 in neuro-oncology
Published in OncoTargets and therapy (01-04-2017)Get full text
Journal Article