Search Results - "Farasat, Alireza"

Calprotectin (S100A8/S100A9): a key protein between inflammation and cancer by Shabani, Fatemeh, Farasat, Alireza, Mahdavi, Majid, Gheibi, Nematollah

“…Background Calprotectin (S100A8/S100A9), a heterodimeric EF-hand Ca 2+  binding protein, are abundant in cytosol of neutrophils and are involved in…”
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In silico assessment of human Calprotectin subunits (S100A8/A9) in presence of sodium and calcium ions using Molecular Dynamics simulation approach by Gheibi, Nematollah, Ghorbani, Mohammad, Shariatifar, Hanifeh, Farasat, Alireza

“…Calprotectin is a heterodimeric protein complex which consists of two subunits including S100A8 and S100A9. This protein has a major role in different…”
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Effects of unsaturated fatty acids (Arachidonic/Oleic Acids) on stability and structural properties of Calprotectin using molecular docking and molecular dynamics simulation approach by Gheibi, Nematollah, Ghorbani, Mohamad, Shariatifar, Hanifeh, Farasat, Alireza

“…Calprotectin is a heterodimeric protein complex with two subunits called S100A8/A9. The protein has an essential role in inflammation process and various human…”
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The effects of the esterified Quercetin with omega3 and omega6 fatty acids on viability, nanomechanical properties, and BAX/BCL-2 gene expression in MCF-7 cells by Soufi, Leila, Farasat, Alireza, Ahmadpour-Yazdi, Hossein, Zolghadr, Leila, Gheibi, Nematollah

“…Quercetin is one of the major flavonoids and it appears to have cytotoxic effects on various cancer cells through regulating the apoptosis pathway genes such…”
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Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL -2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line by Salehi, Mitra, Piri, Hossein, Farasat, Alireza, Pakbin, Babak, Gheibi, Nematollah

“…Humic acid (HA) and Fulvic acid (FA) are major members of humic substances, which are extracted from organic sources including soil and peat. The pro-apoptotic…”
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Identification of Anti-HIV/Migraine Drugs as Potential Inhibitors of SARS-Cov2 Main Protease Using in Silico Assessments by Shariatifar, Hanifeh, Hooshmand, Amir, Gheibi, Nematollah, Farasat, Alireza

“…Background: The acute respiratory syndrome named “COVID-19” is caused by a novel coronavirus called Severe Acute Respiratory Syndrome Coronavirus 2…”
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Finding epitopes of Klebsiella pneumoniae outer membrane protein-K17 (OMPK17) and introducing a 25-mer peptide of it as a vaccine candidate by Ranjbarian, Parivash, Goudarzi, Farjam, Akya, Alisha, Heidarinia, Hana, Farasat, Alireza, Rostamian, Mosayeb

“…No approved vaccine exists for Klebsiella pneumoniae yet. Outer membrane protein-K17 (OMPK17) is involved in K. pneumoniae pathogenesis. No information has…”
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ACE2-Inhibitory Effects of Bromelain and Ficin in Colon Cancer Cells by Pakbin, Babak, Dibazar, Shaghayegh Pishkhan, Allahyari, Samaneh, Shariatifar, Hanifeh, Brück, Wolfram Manuel, Farasat, Alireza

“…: Bromelain and ficin are aqueous extracts from fruits of and plants, used widely for medical applications. Angiotensin-converting enzyme 2 (ACE2) is a homolog…”
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In silico assessment of the inhibitory effect of four flavonoids (Chrysin, Naringin, Quercetin, Kaempferol) on tyrosinase activity using the MD simulation approach by FARASAT, ALIREZA, GHORBANI, MOHAMAD, GHEIB, NEMATOLLAH, SHARIATIFAR, HANIFEH

“…Tyrosinase is a tetrameric enzyme that plays an important role in pigment production. Overproduction of melanin, which may lead to several skin disorders, is a…”
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A Comprehensive Study of Human Serum Albumin Interaction With Trimethoprim Using Molecular Docking and Molecular Dynamics Methods: An Appropriate Tool for Drug Delivery Systems by Salehi, Mitra, Shariatifar, Hanifeh, Ghanbari Johkool, Morteza, Farasat, Alireza

“…Background: Human Serum Albumin (HSA) is one of the most prominent proteins in human blood. Trimethoprim (TMP) is an efficient antibiotic drug for treating…”
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Thermodynamic, kinetic and docking studies of some unsaturated fatty acids-quercetin derivatives as inhibitors of mushroom tyrosinase by Vaezi, Morteza, Rezaei Behbehani, G., Farasat, Alireza, Gheibi, Nematollah

“…Inhibition of activity and stability structure of mushroom tyrosinase (MT) is highly important, since it is a key enzyme of melanogenesis playing various roles…”
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Study of jack bean urease interaction with luteolin by the extended solvation model and docking simulation by Mazinani, Maryam, Rezaei Behbehani, Gholamreza, Gheibi, Nematollah, Farasat, Alireza

“…In this study, the interaction between Luteolin and urease was made at 300 K in aqueous buffer solutions using isothermal titration calorimetry. The extended…”
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Affinity enhancement of CR3022 binding to RBD; in silico site directed mutagenesis using molecular dynamics simulation approaches by Shariatifar, Hanifeh, Farasat, Alireza

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a disease which caused by a novel beta coronavirus. Structural and non-structural proteins are…”
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Enfuvirtide, an HIV-1 fusion inhibitor peptide, can act as a potent SARS-CoV-2 fusion inhibitor: an in silico drug repurposing study by Ahmadi, Khadijeh, Farasat, Alireza, Rostamian, Mosayeb, Johari, Behrooz, Madanchi, Hamid

“…Regarding the urgency of therapeutic measures for coronavirus disease 2019 (COVID-19) pandemic, the use of available drugs with FDA approval is preferred…”
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A comprehensive review on methotrexate containing nanoparticles; an appropriate tool for cancer treatment by Shariatifar, Hanifeh, Ranjbarian, Fateme, Hajiahmadi, Fahimeh, Farasat, Alireza

“…For more than seven decades, methotrexate has been used all over the world for treatment of different diseases such as: cancer, autoimmune diseases, and…”
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A nano-liposomal carrier containing p-coumaric acid for induction of targeted apoptosis on melanoma cells and kinetic modeling by Sabaghi, Yalda, PourFarzad, Farnaz, Zolghadr, Leila, Bahrami, Azita, Shojazadeh, Tahereh, Farasat, Alireza, Gheibi, Nematollah

“…There has been a growth in the use of plant compounds as biological products for the prevention and treatment of various diseases, including cancer. As a…”
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Identification of HLA-I restricted epitopes in six vaccine candidates of Leishmania tropica using immunoinformatics and molecular dynamics simulation approaches by Akya, Alisha, Farasat, Alireza, Ghadiri, Keyghobad, Rostamian, Mosayeb

“…In spite of numerous studies on vaccination for various species of Leishmania, research on the development of an effective vaccine for L. tropica is very…”
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Social structure optimization in team formation by Farasat, Alireza, Nikolaev, Alexander G.

“…This paper presents a mathematical framework for treating the Team Formation Problem explicitly incorporating Social Structure (TFP-SS), the formulation of…”
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Immunoinformatics and molecular dynamics studies to predict T-cell-specific epitopes of four Klebsiella pneumoniae fimbriae antigens by Rostamian, Mosayeb, Farasat, Alireza, Chegene Lorestani, Roya, Nemati Zargaran, Fatemeh, Ghadiri, Keyghobad, Akya, Alisha

“…Klebsiella pneumoniae (K. pneumoniae) is a causative agent of severe infections in humans. There is no publically available vaccine for K. pneumoniae…”
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Anticancer Properties of Probiotic Saccharomyces boulardii Supernatant on Human Breast Cancer Cells by Pakbin, Babak, Dibazar, Shaghayegh Pishkhan, Allahyari, Samaneh, Javadi, Maryam, Amani, Zahra, Farasat, Alireza, Darzi, Sina

“…Saccharomyces boulardii , a variety of S. cerevisiae , is used as a probiotic yeast in food and drug industries. However, S. boulardii is an opportunistic…”
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